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  • Rosén, AnnaUmeå universitet,Epidemiologi och global hälsa,Umeå University, Sweden (författare)

Usefulness of symptoms to screen for celiac disease

  • Artikel/kapitelEngelska2014

Förlag, utgivningsår, omfång ...

  • 2014-02-01
  • American Academy of Pediatrics (AAP),2014
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-88852
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88852URI
  • https://doi.org/10.1542/peds.2012-3765DOI
  • https://lup.lub.lu.se/record/4470362URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:129003881URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-107468URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • OBJECTIVE: To describe the frequency of symptoms and associated conditions among screening-detected celiac disease (CD) cases and non-CD children and to evaluate questionnaire-based case-finding targeting the general population.METHODS: In a population-based CD screening of 12-year-olds, children and their parents completed questionnaires on CD-associated symptoms and conditions before knowledge of CD status. Questionnaire data for those who had their CD detected in the screening (n = 153) were compared with those of children with normal levels of CD markers (n = 7016). Hypothetical case-finding strategies were also evaluated. Questionnaires were returned by 7054 (98%) of the children and by 6294 (88%) of their parents.RESULTS: Symptoms were as common among screening-detected CD cases as among non-CD children. The frequency of children with screening-detected CD was similar when comparing the groups with and without any CD-related symptoms (2.1% vs 2.1%; P = .930) or CD-associated conditions (3.6% vs 2.1%; P = .07). Case-finding by asking for CD-associated symptoms and/or conditions would have identified 52 cases (38% of all cases) at a cost of analyzing blood samples for 2282 children (37%) in the study population.CONCLUSIONS: The current recommended guidelines for finding undiagnosed CD cases, so-called active case-finding, fail to identify the majority of previously undiagnosed cases if applied in the general population of Swedish 12-year-olds. Our results warrant further studies on the effectiveness of CD case-finding in the pediatric population, both at the clinical and population-based levels.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Sandström, OlofUmeå universitet,Pediatrik,Umeå University, Sweden(Swepub:umu)olsa0022 (författare)
  • Carlsson, AnnelieLund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund University, Sweden,Umeå University, Sweden(Swepub:lu)med-acs (författare)
  • Högberg, LottaÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Barn- och ungdomskliniken i Norrköping(Swepub:liu)lotho28 (författare)
  • Olén, OlaKarolinska Institutet,Karolinska Institute, Sweden Sachs Children and Youth Hospital, Sweden (författare)
  • Stenlund, HansUmeå universitet,Epidemiologi och global hälsa,Umeå University, Sweden(Swepub:umu)hast0001 (författare)
  • Ivarsson, AnneliUmeå universitet,Epidemiologi och global hälsa(Swepub:umu)aniv0001 (författare)
  • Umeå universitetEpidemiologi och global hälsa (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Pediatrics: American Academy of Pediatrics (AAP)133:2, s. 211-2180031-40051098-4275

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