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Dietary intake of a...
Dietary intake of acrylamide and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort
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Obón-Santacana, M. (author)
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Kaaks, R. (author)
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Slimani, N. (author)
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show more...
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Lujan-Barroso, L. (author)
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Freisling, H. (author)
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Ferrari, P. (author)
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Dossus, L. (author)
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Chabbert-Buffet, N. (author)
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Baglietto, L. (author)
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Fortner, R. T. (author)
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Boeing, H. (author)
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Tjønneland, A. (author)
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Olsen, A. (author)
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Overvad, K. (author)
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Menéndez, V. (author)
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Molina-Montes, E. (author)
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Larrañaga, N. (author)
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Chirlaque, M-D (author)
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Ardanaz, E. (author)
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Khaw, K-T (author)
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Wareham, N. (author)
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Travis, R. C. (author)
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- Lu, Y. (author)
- Karolinska Institutet
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Merritt, M. A. (author)
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Trichopoulou, A. (author)
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Benetou, V. (author)
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Trichopoulos, D. (author)
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Saieva, C. (author)
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Sieri, S. (author)
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Tumino, R. (author)
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Sacerdote, C. (author)
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Galasso, R. (author)
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Bueno-de-Mesquita, H. B. (author)
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- Wirfält, Elisabet (author)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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- Ericson, Ulrika (author)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Nutritionsepidemiologi,Diabetes - Cardiovascular Disease,Lund University Research Groups,Nutrition Epidemiology
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- Idahl, Annika (author)
- Umeå universitet,Obstetrik och gynekologi,Näringsforskning
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- Ohlson, Nina (author)
- Umeå universitet,Patologi
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Skeie, G. (author)
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Gram, I. T. (author)
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- Weiderpass, E. (author)
- Karolinska Institutet
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Onland-Moret, N. C. (author)
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Riboli, E. (author)
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Duell, E. J. (author)
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(creator_code:org_t)
- 2014-06-17
- 2014
- English.
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In: British Journal of Cancer. - : Nature Publishing Group. - 0007-0920 .- 1532-1827. ; 111:5, s. 987-997
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https://portal.resea... (primary) (free)
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http://www.ncbi.nlm....
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- BACKGROUND: Three prospective studies have evaluated the association between dietary acrylamide intake and endometrial cancer (EC) risk with inconsistent results. The objective of this study was to evaluate the association between acrylamide intake and EC risk: for overall EC, for type-I EC, and in never smokers and never users of oral contraceptives (OCs). Smoking is a source of acrylamide, and OC use is a protective factor for EC risk. METHODS: Cox regression was used to estimate hazard ratios (HRs) for the association between acrylamide intake and EC risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Acrylamide intake was estimated from the EU acrylamide monitoring database, which was matched with EPIC questionnaire-based food consumption data. Acrylamide intake was energy adjusted using the residual method. RESULTS: No associations were observed between acrylamide intake and overall EC (n = 1382) or type-I EC risk (n = 627). We observed increasing relative risks for type-I EC with increasing acrylamide intake among women who both never smoked and were non-users of OCs (HRQ5vsQ1: 1.97, 95% CI: 1.08-3.62; likelihood ratio test (LRT) P-value: 0.01, n = 203). CONCLUSIONS: Dietary intake of acrylamide was not associated with overall or type-I EC risk; however, positive associations with type I were observed in women who were both non-users of OCs and never smokers.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- acrylamide
- endometrial cancer
- type-I endometrial cancer
- cohort
- nutrition
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Obón-Santacana, ...
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Kaaks, R.
-
Slimani, N.
-
Lujan-Barroso, L ...
-
Freisling, H.
-
Ferrari, P.
-
show more...
-
Dossus, L.
-
Chabbert-Buffet, ...
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Baglietto, L.
-
Fortner, R. T.
-
Boeing, H.
-
Tjønneland, A.
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Olsen, A.
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Overvad, K.
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Menéndez, V.
-
Molina-Montes, E ...
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Larrañaga, N.
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Chirlaque, M-D
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Ardanaz, E.
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Khaw, K-T
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Wareham, N.
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Travis, R. C.
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Lu, Y.
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Merritt, M. A.
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Trichopoulou, A.
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Benetou, V.
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Trichopoulos, D.
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Saieva, C.
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Sieri, S.
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Tumino, R.
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Sacerdote, C.
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Galasso, R.
-
Bueno-de-Mesquit ...
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Wirfält, Elisabe ...
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Ericson, Ulrika
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Idahl, Annika
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Ohlson, Nina
-
Skeie, G.
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Gram, I. T.
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Weiderpass, E.
-
Onland-Moret, N. ...
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Riboli, E.
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Duell, E. J.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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British Journal ...
- By the university
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Umeå University
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Lund University
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Karolinska Institutet