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Search: WFRF:(Gerard Benedicte) > (2011-2014) > Cross-sectional ass...

  • Cai, Yutong (author)

Cross-sectional associations between air pollution and chronic bronchitis : an ESCAPE meta-analysis across five cohorts

  • Article/chapterEnglish2014

Publisher, publication year, extent ...

  • 2014-08-11
  • BMJ,2014
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-95713
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-95713URI
  • https://doi.org/10.1136/thoraxjnl-2013-204352DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • BACKGROUND: This study aimed to assess associations of outdoor air pollution on prevalence of chronic bronchitis symptoms in adults in five cohort studies (Asthma-E3N, ECRHS, NSHD, SALIA, SAPALDIA) participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE) project.METHODS: Annual average particulate matter (PM10, PM2.5, PMabsorbance, PMcoarse), NO2, nitrogen oxides (NOx) and road traffic measures modelled from ESCAPE measurement campaigns 2008-2011 were assigned to home address at most recent assessments (1998-2011). Symptoms examined were chronic bronchitis (cough and phlegm for ≥3 months of the year for ≥2 years), chronic cough (with/without phlegm) and chronic phlegm (with/without cough). Cohort-specific cross-sectional multivariable logistic regression analyses were conducted using common confounder sets (age, sex, smoking, interview season, education), followed by meta-analysis.RESULTS: 15 279 and 10 537 participants respectively were included in the main NO2 and PM analyses at assessments in 1998-2011. Overall, there were no statistically significant associations with any air pollutant or traffic exposure. Sensitivity analyses including in asthmatics only, females only or using back-extrapolated NO2 and PM10 for assessments in 1985-2002 (ECRHS, NSHD, SALIA, SAPALDIA) did not alter conclusions. In never-smokers, all associations were positive, but reached statistical significance only for chronic phlegm with PMcoarse OR 1.31 (1.05 to 1.64) per 5 µg/m(3) increase and PM10 with similar effect size. Sensitivity analyses of older cohorts showed increased risk of chronic cough with PM2.5abs (black carbon) exposures.CONCLUSIONS: Results do not show consistent associations between chronic bronchitis symptoms and current traffic-related air pollution in adult European populations.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Schikowski, Tamara (author)
  • Adam, Martin (author)
  • Buschka, Anna (author)
  • Carsin, Anne-Elie (author)
  • Jacquemin, Benedicte (author)
  • Marcon, Alessandro (author)
  • Sanchez, Margaux (author)
  • Vierkötter, Andrea (author)
  • Al-Kanaani, Zaina (author)
  • Beelen, Rob (author)
  • Birk, Matthias (author)
  • Brunekreef, Bert (author)
  • Cirach, Marta (author)
  • Clavel-Chapelon, Françoise (author)
  • Declercq, Christophe (author)
  • de Hoogh, Kees (author)
  • de Nazelle, Audrey (author)
  • Ducret-Stich, Regina E. (author)
  • Valeria Ferretti, Virginia (author)
  • Forsberg, BertilUmeå universitet,Yrkes- och miljömedicin,Arcum(Swepub:umu)befo0001 (author)
  • Gerbase, Margaret W. (author)
  • Hardy, Rebecca (author)
  • Heinrich, Joachim (author)
  • Hoek, Gerard (author)
  • Jarvis, Debbie (author)
  • Keidel, Dirk (author)
  • Kuh, Diana (author)
  • Nieuwenhuijsen, Mark J. (author)
  • Ragettli, Martina S. (author)
  • Ranzi, Andrea (author)
  • Rochat, Thierry (author)
  • Schindler, Christian (author)
  • Sugiri, Dorothea (author)
  • Temam, Sofia (author)
  • Tsai, Ming-Yi (author)
  • Varraso, Raphaëlle (author)
  • Kauffmann, Francine (author)
  • Krämer, Ursula (author)
  • Sunyer, Jordi (author)
  • Künzli, Nino (author)
  • Probst-Hensch, Nicole (author)
  • Hansell, Anna L. (author)
  • Umeå universitetYrkes- och miljömedicin (creator_code:org_t)

Related titles

  • In:Thorax: BMJ69:11, s. 1005-10140040-63761468-3296

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