Endoscopic Treatment With Stabilized Nonanimal Hyaluronic Acid/Dextranomer Gel is Effective in Vesicoureteral Reflux Associated With Bladder Dysfunction

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Läckgren, Göran,1942-Uppsala universitet,Barnkirurgi (författare)

Endoscopic Treatment With Stabilized Nonanimal Hyaluronic Acid/Dextranomer Gel is Effective in Vesicoureteral Reflux Associated With Bladder Dysfunction

Artikel/kapitelEngelska2007

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Ovid Technologies (Wolters Kluwer Health),2007
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LIBRIS-ID:oai:DiVA.org:uu-104908
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-104908URI
https://doi.org/10.1016/j.juro.2006.10.094DOI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

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PURPOSE: Endoscopic injection of stabilized nonanimal hyaluronic acid/dextranomer gel is an established treatment for vesicoureteral reflux in children. We performed a subgroup analysis to assess this treatment in reflux associated with bladder dysfunction. MATERIALS AND METHODS: Of 308 consecutive children treated endoscopically with stabilized nonanimal hyaluronic acid/dextranomer gel for dilating vesicoureteral reflux 54 were observed retrospectively to have bladder dysfunction. Initial followup consisted of voiding cystourethrogram at 3 and 12 months after injection, with positive response defined as reflux grade 0 or I. At 7 to 12 years following treatment patient charts were checked for urinary tract infections and bladder dysfunction, and a followup survey (postal questionnaire) was administered. RESULTS: A positive response to therapy (cure) was observed in 45 children (83%) after 1 to 3 endoscopic treatments. Concurrently, bladder dysfunction had resolved in 32 patients (59%). After the last stabilized nonanimal hyaluronic acid/dextranomer gel implantation 45 patients (83%) were free of urinary tract infections. Questionnaire results were similar to chart based findings. Stabilized nonanimal hyaluronic acid/dextranomer gel implantation was well tolerated, with no associated complications. CONCLUSIONS: Endoscopic treatment with stabilized nonanimal hyaluronic acid/dextranomer gel appears to be similarly effective in patients with vesicoureteral reflux with and without bladder dysfunction. These data indicate that bladder dysfunction should not be considered a contraindication to endoscopic treatment for reflux.

Ämnesord och genrebeteckningar

NASHA-Dx copolymer
vesico-ureteral reflux
bladder
endoscopy
child
MEDICINE
MEDICIN
Kirurgi, särskilt urologi
Urology

Biuppslag (personer, institutioner, konferenser, titlar ...)

Sköldenberg, ErikUppsala universitet,Barnkirurgi(Swepub:uu)erikskol (författare)
Stenberg, Arne,1948-Uppsala universitet,Barnkirurgi(Swepub:uu)arnesten (författare)
Uppsala universitetBarnkirurgi (creator_code:org_t)

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Ingår i:Journal of Urology: Ovid Technologies (Wolters Kluwer Health)177:3, s. 1124-11290022-53471527-3792

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Av författaren/redakt...: Läckgren, Göran, ...; Sköldenberg, Eri ...; Stenberg, Arne, ...

Artiklar i publikationen: Journal of Urolo ...

Av lärosätet: Uppsala universitet

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