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Temporal trends of ...
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Lindehammer, SabinaLund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups,Dept. of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden,Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden
(author)
Temporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk
- Article/chapterEnglish2008
Publisher, publication year, extent ...
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2008-09-04
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Springer Science and Business Media LLC,2008
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-105693
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-105693URI
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https://doi.org/10.1007/s00592-008-0048-5DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-3514URI
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https://lup.lub.lu.se/record/1243373URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-43465URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:117787131URI
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https://gup.ub.gu.se/publication/84609URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The Swedish Childhood Diabetes Study GroupM. Aili, Halmstad; L.E. Ba ̊a ̊th, Östersund; E. Carlsson,Kalmar; H. Edenwall, Karlskrona; G. Forsander, Falun; BW. Granström, Gällivare; I. Gustavsson, Skellefteå; R. Hanås, Uddevalla; L. Hellenberg, Nyköping; H. Hellgren, Lidköping; E. Holmberg, Umeå; H.Hörnell, Hudiksvall; Sten-A. Ivarsson, Malmö; C. Johansson, Jönköping; G. Jonsell, Karlstad; K. Kockum, Ystad; B.Lindblad, Mölndal; A. Lindh, Borås; J. Ludvigsson, Linköping; U. Myrdal, Västerås; J. Neiderud, Helsingborg; K. Segnestam, Eskilstuna; S. Sjöblad, Lund; L. Skogsberg, Boden; L. Strömberg, Norrköping; U. Ståhle, Ängelholm; B. Thalme, Huddinge; K. Tullus, Danderyd; T. Tuvemo, Uppsala; M. Wallensteen, Stockholm; O. Westphal, Göteborg and J. Åman, Örebro. All from Departments of Pediatrics in Sweden.
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The aim of this study was to compare the frequency of human leukocyte antigen (HLA) genotypes in 1-18-year-old patients with type 1 diabetes newly diagnosed in 1986-1987 (n = 430), 1996-2000 (n = 342) and in 2003-2005 (n = 171). We tested the hypothesis that the HLA DQ genotype distribution changes over time. Swedish type 1 diabetes patients and controls were typed for HLA using polymerase chain reaction amplification and allele specific probes for DQ A1* and B1* alleles. The most common type 1 diabetes HLA DQA1*-B1*genotype 0501-0201/0301-0302 was 36% (153/430) in 1986-1987 and 37% (127/342) in 1996-2000, but decreased to 19% (33/171) in 2003-2005 (P \ 0.0001). The 0501-0201/0501-0201 genotype increased from 1% in 1986-1987 to 7% in 1996-2000 (P = 0.0047) and to 5% in 2003-2005 (P > 0.05). This study in 1-18-year-old Swedish type 1 diabetes patients supports the notion that there is a temporal change in HLA risk.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Larsson, KarinLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Department of Pediatrics, Kristianstad Hospital, Kristianstad, Sweden(Swepub:lu)med-kil
(author)
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Örtqvist, E.Karolinska Institutet
(author)
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Carlsson, AnnelieLund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Dept. of Pediatrics, Malmö, Sweden,Department of Clinical Sciences, Unit of Pediatrics, University Hospital, Lund University, Malmö, Sweden(Swepub:lu)med-acs
(author)
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Cederwall, E.Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden,Dept. of Pediatrics, Karlskrona, Sweden
(author)
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Cilio, CorradoLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Dept. of Pediatrics, Jönköping, Sweden,Department of Clinical Sciences, Cellular Autoimmunity Unit, University Hospital, Lund University, Malmö, Sweden(Swepub:lu)endo-cci
(author)
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Sjöblad, StureLund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Dept. of Pediatrics, Lund, Sweden,Department of Clinical Sciences, Unit of Pediatrics, University Hospital, Lund University, Malmö, Sweden(Swepub:lu)st6585sj
(author)
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Jönsson, B. A.Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden,Dept. of Pediatrics, Örebro, Sweden
(author)
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Larsson, HelenaLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Department of Clinical Sciences, Unit of Pediatrics, University Hospital, Lund University, Malmö, Sweden(Swepub:lu)pedi-hla
(author)
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Lynch, KristianLund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups,Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden(Swepub:lu)endo-kly
(author)
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Neiderud, JanLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Dept. of Pediatrics, Helsingborg, Sweden,Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden(Swepub:lu)med-jnu
(author)
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Nilsson, AnnaLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden(Swepub:lu)med-ann
(author)
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Sjöblad, S.
(author)
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Lernmark, ÅkeLund University,Lunds universitet,Celiaki och diabetes,Forskargrupper vid Lunds universitet,Celiac Disease and Diabetes Unit,Lund University Research Groups,Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, University Hospital MAS, CRC/Lund University, Malmö, Sweden; Department of Medicine, University of Washington, Seattle, WA, USA(Swepub:lu)endo-ale
(author)
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Aili, M.Dept. of Pediatrics, Halmstad, Sweden
(author)
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Bååth, L. E.Dept. of Pediatrics, Östersund, Sweden,Dept. of Pediatrics, Mölndal, Sweden
(author)
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Carlsson, E.Dept. of Pediatrics, Kalmar, Sweden
(author)
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Edenwall, H.Dept. of Pediatrics, Karlskrona, Sweden,Dept. of Pediatrics, Umeå, Sweden
(author)
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Forsander, Gun,1951Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xfgunj
(author)
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Granstro, B. W.Dept. of Pediatrics, Gällivare, Sweden
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Gustavsson, I.Dept. of Pediatrics, Skellefteå, Sweden
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Hanås, R.Dept. of Pediatrics, Uddevalla, Sweden
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Hellenberg, L.Dept. of Pediatrics, Nyköping, Sweden
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Hellgren, H.Dept. of Pediatrics, Lidköping, Sweden,Dept. of Pediatrics, Hudiksvall, Sweden
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Holmberg, E.Dept. of Pediatrics, Umeå, Sweden
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Hörnell, H.Dept. of Pediatrics, Hudiksvall, Sweden
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Ivarsson, Sten-A.Dept. of Pediatrics, Malmö, Sweden
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Johansson, C.Dept. of Pediatrics, Jönköping, Sweden
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Jonsell, G.Dept. of Pediatrics, Karlstad, Sweden
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Kockum, K.Dept. of Pediatrics, Ystad, Sweden,Dept. of Pediatrics, Skilstuna, Sweden,Dept. of Pediatrics, Danderyd, Sweden
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Lindblad, Birgitta Ejdervik,1955-Dept. of Pediatrics, Mölndal, Sweden,Swedish Childhood Diabetes Study Group(Swepub:oru)baed
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Lindh, A.Dept. of Pediatrics, Borås, Sweden
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Ludvigsson, Jonas F.,1969-Dept. of Pediatrics, Linköping, Sweden,Swedish Childhood Diabetes Study Group(Swepub:oru)jsln
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Myrdal, U.Dept. of Pediatrics, Västerås, Sweden
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Neiderud, J.Dept. of Pediatrics, Helsingborg, Sweden
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Segnestam, K.Dept. of Pediatrics, Skilstuna, Sweden
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Sjöblad, S.Dept. of Pediatrics, Lund, Sweden
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Skogsberg, L.Dept. of Pediatrics, Boden, Sweden
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Strömberg, L.Dept. of Pediatrics, Norrköping, Sweden
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Ståhle, U.Dept. of Pediatrics, Ängelholm, Sweden
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Thalme, B.Dept. of Pediatrics, Huddinge, Sweden
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Tullus, K.Dept. of Pediatrics, Danderyd, Sweden
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Tuvemo, TorstenUppsala universitet,Institutionen för kvinnors och barns hälsa,Barnendokrinologisk forskning/Gustafsson(Swepub:uu)torstuve
(author)
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Wallensteen, M.Dept. of Pediatrics, Stockholm, Sweden
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Westphal, Otto,1935Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xwesot
(author)
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Åman, Jan,1948-Örebro universitet,Hälsoakademin,Swedish Childhood Diabetes Study Group(Swepub:oru)jnaa
(author)
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Lindblad, BengtGothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences(Swepub:gu)xliben
(author)
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Celiaki och diabetesForskargrupper vid Lunds universitet
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In:Acta Diabetologica: Springer Science and Business Media LLC45:4, s. 231-50940-54291432-5233
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Lindehammer, Sab ...
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Larsson, Karin
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Örtqvist, E.
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Carlsson, Anneli ...
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Cederwall, E.
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Cilio, Corrado
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Sjöblad, Sture
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Jönsson, B. A.
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Larsson, Helena
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Lynch, Kristian
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Neiderud, Jan
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Nilsson, Anna
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Sjöblad, S.
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Lernmark, Åke
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Aili, M.
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Bååth, L. E.
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Carlsson, E.
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Edenwall, H.
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Forsander, Gun, ...
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Granstro, B. W.
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Gustavsson, I.
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Hanås, R.
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Hellenberg, L.
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Hellgren, H.
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Holmberg, E.
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Hörnell, H.
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Ivarsson, Sten-A ...
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Johansson, C.
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Jonsell, G.
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Kockum, K.
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Lindblad, Birgit ...
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Lindh, A.
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Ludvigsson, Jona ...
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Myrdal, U.
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Neiderud, J.
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Segnestam, K.
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Skogsberg, L.
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Strömberg, L.
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Ståhle, U.
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Thalme, B.
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Tullus, K.
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Tuvemo, Torsten
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Wallensteen, M.
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Westphal, Otto, ...
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Åman, Jan, 1948-
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Lindblad, Bengt
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