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  • Moen, Janne,1980-Uppsala universitet,Institutionen för farmaci,Pharmaceutical Outcomes Research Group (author)

Multiple medicine use: factors of importance in different age groups

  • BookEnglish

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  • LIBRIS-ID:oai:DiVA.org:uu-106348
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-106348URI

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  • Language:English
  • Summary in:English

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  • Subject category:vet swepub-contenttype
  • Subject category:ovr swepub-publicationtype

Notes

  • BACKGROUND: Multiple medicine use among elderly persons is likely to be the result of treatment regimens developed over a long time. By learning more about this development, it might be possible to increase quality in management of multiple medicine use across the adult lifespan. OBJECTIVE: To describe patterns of multiple medicine use in a general population in association with sociodemographic factors, lifestyle, and health status. METHODS: Data from a cross-sectional population health survey collected during 2001-2005 in 2,816 randomly selected Swedish residents (age 30-75 years; response rate 76%). Multiple medicine use was defined as the upper quartile in each age cohort. RESULTS: The cut-offs defining multiple medicine use were: ≥2 for 30-49 year olds, ≥3 for 50-64 year olds, and ≥5 for 65-75 year olds. When drugs were classified into the second level of the ATC code, 76.3% of the 30-49 year olds, 97.9% of the 50-64 year olds, and 100% of the 65-75 year olds used a unique combination of drugs. The multivariate analyses showed that diabetes and poor self-rated health were associated with multiple medicine use in all age cohorts. Female gender and hypertension were associated with multiple medicine use among 30-49 and 50-64 year olds, ex-smoking among 50-64 year olds, and obesity among 65-75 year olds. CONCLUSIONS: Different cut-offs should be used in defining multiple medicine use in different age groups. A vast majority of users of multiple medicines have a unique drug combination. Multiple medicine use is associated with morbidity and poor self-rated health across all age groups, suggesting that multiple medicine use is not due to drug over-consumption.

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  • Antonov, KarolinaThe Swedish Association of the Pharmaceutical Industry,Pharmaceutical Outcomes Research Group (author)
  • Larsson, Charlotte A.Department of Clinical Sciences, Lund University (author)
  • Lindblad, UlfDepartment of Public Health and Community Medicine/Primary Health Care, The Sahlgrenska Academy at Gothenburg University and The Skaraborg Institute (author)
  • Nilsson, J. Lars G.The NEPI Foundation (author)
  • Råstam, LennartDepartment of Clinical Sciences, Lund University (author)
  • Ring, LenaUppsala universitet,Institutionen för farmaci,Pharmaceutical Outcomes Research Group (author)
  • Uppsala universitetInstitutionen för farmaci (creator_code:org_t)

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