Acute Effects of Some Volatile Organic Compounds Emitted From Waters-Based Paints

OBJECTIVE: Acute effects during controlled exposure to some of the volatile organic compounds emitted from water-based paints were evaluated. METHODS: Healthy volunteers (10 atopics, 10 nonatopics, and 10 painters) were exposed to a mixture of propyleneglycol, texanol, diethyleneglycol monoethylether, diethyleneglycol monobutyl ether, and dipropyleneglycol monomethyl ether at a total concentration of 35 mg/m3 (G), a mixture of G and ammonia (15 mg/m3) (GA), and clean air (C). RESULTS: Subjective ratings of irritation in eyes, nose, throat, and dyspnea were significantly higher during the G and GA conditions, when compared with during the C condition. Nasal mucosal swelling was observed after G but not after GA exposure. No effects of the exposure on the pulmonary function, markers of inflammation in nasal lavages, and renal function in urine were seen. CONCLUSION: Exposure to G and GA caused mild irritation in eyes, nose, and airways.

Löf, Agneta E. (författare)
Wieslander, GunillaUppsala universitet,Arbets- och miljömedicin,Eva Vingård(Swepub:uu)guniwies (författare)
Norbäck, DanUppsala universitet,Arbets- och miljömedicin,Eva Vingård(Swepub:uu)dagnorba (författare)
Johanson, GunnarKarolinska Institutet (författare)
Karolinska InstitutetArbets- och miljömedicin (creator_code:org_t)

Ingår i:Journal of Occupational and Environmental Medicine49:8, s. 880-8891076-27521536-5948

Av författaren/redakt...: Ernstgård, Lena; Löf, Agneta E.; Wieslander, Guni ...; Norbäck, Dan; Johanson, Gunnar

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