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The Clinical Impact of Fetal Magnetic Resonance Imaging on Management of Non-CNS Anomalies in the Second Trimester of Pregnancy

Amini, Hashem, 1960- (author)
Uppsala universitet,Institutionen för kvinnors och barns hälsa,Obstetrik & gynekologi,Obstetrik
Wikström, Johan (author)
Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Enheten för radiologi
Ahlström, Håkan (author)
Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi,Enheten för radiologi
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Axelsson, Ove (author)
Uppsala universitet,Institutionen för kvinnors och barns hälsa,Obstetrik & gynekologi,Obstetrik
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 (creator_code:org_t)
English.
  • Other publication (other academic/artistic)
Abstract Subject headings
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  • Objectives: To evaluate the additional information of second trimester MRI compared to ultrasound in fetuses with identified or suspected non-CNS anomalies and to study the clinical impact of the MRI information on pregnancy management. Methods: Sixty-three women were included, where the second trimester ultrasound identified or raised suspicion of fetal anomalies. Ultrasound was compared to MRI in relation to the final diagnosis, fetal autopsy if performed or postnatal diagnosis. The additional information of MRI and effect on pregnancy management was estimated in consensus. Results: The mean gestational age at the last ultrasound before MRI was 18+1 weeks (range 13+0-21+5). The mean interval between ultrasound and MRI was 2.6 days (range 0-15). In 42 (67 %) cases MRI was performed within three days. All MRI examinations were assessable. In 43 (68 %) fetuses MRI provided no additional information, in 17 (27 %) MRI added information without changing the management and in three (5 %) MRI provided additional information which changed the management. These three cases had all oligohydramnios. In all six cases of diaphragmatic hernia MRI provided additional information. Conclusions: Fetal MRI of non-CNS anomalies is feasible in the second trimester and gives additional information in nearly a third of cases. It may provide a clinically valuable adjunct to ultrasound especially in cases of diaphragmatic hernia or oligohydramnios.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)

Keyword

Fetal MRI
non-CNS anomalies
second trimester
ultrasound
pregnancy management
antenatal diagnosis
Obstetrics and gynaecology
Obstetrik och gynekologi
Obstetrics and Gynaecology
Obstetrik och gynekologi

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vet (subject category)
ovr (subject category)

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