Drug use patterns in a very elderly population: a seven-year review

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Giron, MST (author)

Drug use patterns in a very elderly population : a seven-year review

Article/chapterEnglish1999

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1999
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LIBRIS-ID:oai:DiVA.org:uu-126492
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-126492URI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Objective: To determine the extent and rate of drug use and to evaluate the patterns of drug use over time in a very elderly population, we analysed drug use data from phases I (1987-1989) and IV (1994-1996) of the Kungsholmen project, an ongoing longitudinal study on aging in Stockholm, Sweden.Study Participants: Complete drug information was obtained from 1001 subjects in the 1987-1989 study period, and 681 subjects in 1994-1996. The participants were predominantly women and the average age was 85.8 years in 1987-1989 and 86.9 years in 1994-1996.Results: The proportion of users increased from 87.6 to 94.1% and the overall average number of drugs used per subject increased significantly (p < 0.001) from 3.4 to 4.6. Significant differences (p < 0.05) were noted in all age groups and in all types of housing. The frequency of use increased for all classes of drugs. The most frequently used in both study periods were drugs for the nervous system, cardiovascular system, and alimentary tract and metabolism. With regard to therapeutic categories of drugs, the use of vitamins, antithrombotic agents, antianaemic preparations, ACE inhibitors, antibacterials, analgesics, psychoanaleptics, and antiglaucoma preparations increased significantly (p < 0.05). The increased use of these drugs indicated heightened awareness of the most common and preventable medical conditions affecting the elderly and the use of newer classes of drugs. This also study confirmed a high prevalence of drug use and polypharmacy even in the very elderly, and the importance of evaluating the effects and appropriateness of drug use in this population.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Farmaceutiska vetenskaper hsv//swe
MEDICAL AND HEALTH SCIENCES Basic Medicine Pharmaceutical Sciences hsv//eng
Elderly
Drug-utilisation
Pharmacoeconomics
PHARMACY
FARMACI

Added entries (persons, corporate bodies, meetings, titles ...)

Claesson, Cecilia BNational Board of Health and Welfare, Stockholm, Sweden(Swepub:uu)ceber226 (author)
Thorslund, Mats (author)
Oke, Thimothy (author)
Winblad, Bengt (author)
Fastbom, Johan (author)
National Board of Health and Welfare, Stockholm, Sweden (creator_code:org_t)

Related titles

In:Clinical drug investigation17:15, s. 389-981173-25631179-1918

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By the author/editor: Giron, MST; Claesson, Cecili ...; Thorslund, Mats; Oke, Thimothy; Winblad, Bengt; Fastbom, Johan

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Pharmaceutical S ...

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