Validation of a home environment test battery for supporting assessments in advanced Parkinson’s disease

Westin, Jerker,1971-Högskolan Dalarna,Uppsala universitet,Biomedicinsk informatik och teknik,Academy of Industry and Society, Computer Science, Dalarna University, Borlänge, Sweden; Department of Medical Sciences, Biomedical Informatics and Engineering, Uppsala University, Uppsala, Sweden,Datateknik (author)

Funding Agencies:Solvay Pharmaceuticals Allschwil, Switzerland Nordforce Technology Stockholm Sweden
Test sequences in a test battery for Parkinson's disease patients, consisting of self-assessments and motor tests, were carried out repeatedly in a telemedicine setting, during week-long test periods and results were summarized in an 'overall score'. 35 patients in stable and fluctuating conditions (15 age- and gender-matched pairs) used the test battery for 1 week, and were then assessed with UPDRS and PDQ-39. This procedure was repeated 1 week later, without treatment changes. Reliability was assessed by intraclass correlation coefficients and Cronbach's alpha. Convergent validity was assessed by Spearman rank correlations and known-groups' validity, by the Mann-Whitney test. According to anonymous usability questionnaires, the patients could easily complete the tasks. Median compliance (93%) and test-retest reliability (0.88) were good. The correlations between overall score and total UPDRS (-0.64) and PDQ-39 (-0.72) were adequate. Median overall score was 18% better in the stable compared to the fluctuating group (p = 0.0014).

Schiavella, MauroParkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy (author)
Memedi, Mevludin,1983-Högskolan Dalarna,Datateknik(Swepub:du)mmi (author)
Nyholm, DagUppsala universitet,Neurologi,Department of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden(Swepub:uu)danyh856 (author)
Dougherty, MarkHögskolan Dalarna,Datateknik(Swepub:du)mdo (author)
Antonini, AngeloParkinson Institute, Istituti Clinici di Perfezionamento, Milan, Italy; Department for Parkinson's Disease, IRCCS San Camillo, Venice, Italy (author)
Uppsala universitetBiomedicinsk informatik och teknik (creator_code:org_t)

In:Neurological SciencesMilano : Springer Science and Business Media LLC33:4, s. 831-8381590-18741590-3478

By the author/editor: Westin, Jerker, ...; Schiavella, Maur ...; Memedi, Mevludin ...; Nyholm, Dag; Dougherty, Mark; Antonini, Angelo

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Medical Biotechn ...; and Biomedical Labor ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Neurology

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