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Centralization of r...
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Khani, M. HosseinaliUppsala universitet,Centrum för klinisk forskning, Västerås
(författare)
Centralization of rectal cancer surgery improves long-term survival
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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2009-10-30
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Wiley,2010
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-135406
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-135406URI
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https://doi.org/10.1111/j.1463-1318.2009.02098.xDOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Aim In 1996, rectal cancer surgery in the Swedish county of Vastmanland was centralized to a single colorectal unit. At the same time, total mesorectal excision and multidisciplinary team meetings were introduced. The aim of this audit was to determine the long-term results before and after centralization. Method All consecutive rectal cancer patients who underwent curative or palliative surgery at one of the county's four hospitals between 1993 and 1996 (n = 133, group 1) were compared with patients operated at the new centralized colorectal unit between 1996 and 1999 (n = 144, group 2). Results Preoperative radiotherapy was common in both groups, but in group 2, it was planned using MRI. Local recurrences were detected in 8% of all patients operated in group 1 vs 3.5% in group 2 (P = 0.043). The overall 5-year survival for all patients in group 1 was 38 vs 62% in group 2 (P = 0.003). According to multivariate analysis, the new colorectal unit was an independent predictor for improved long-term survival. Conclusion This population-based audit shows reduced local recurrence rate and prolonged overall survival for rectal cancer patients after centralization to a single colorectal unit with multidisciplinary management and increased subspecialization.
Ämnesord och genrebeteckningar
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Rectal cancer
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surgery
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centralization
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survival
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MEDICINE
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MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Smedh, KennetUppsala universitet,Centrum för klinisk forskning, Västerås(Swepub:uu)kensm722
(författare)
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Uppsala universitetCentrum för klinisk forskning, Västerås
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Colorectal Disease: Wiley12:9, s. 874-8791462-89101463-1318
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