Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32

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Conde, Lucia (author)

Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32

Article/chapterEnglish2010

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2010-07-18
Springer Science and Business Media LLC,2010
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LIBRIS-ID:oai:DiVA.org:uu-135598
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-135598URI
https://doi.org/10.1038/ng.626DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:121097189URI

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Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

To identify susceptibility loci for non-Hodgkin lymphoma subtypes, we conducted a three-stage genome-wide association study. We identified two variants associated with follicular lymphoma at 6p21.32 (rs10484561, combined P = 1.12 x 10(-29) and rs7755224, combined P = 2.00 x 10(-19); r(2) = 1.0), supporting the idea that major histocompatibility complex genetic variation influences follicular lymphoma susceptibility. We also found confirmatory evidence of a previously reported association between chronic lymphocytic leukemia/small lymphocytic lymphoma and rs735665 (combined P = 4.24 x 10(-9)).

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MEDICINE
MEDICIN

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Halperin, Eran (author)
Akers, Nicholas K. (author)
Brown, Kevin M. (author)
Smedby, Karin E.Karolinska Institutet (author)
Rothman, Nathaniel (author)
Nieters, Alexandra (author)
Slager, Susan L. (author)
Brooks-Wilson, Angela (author)
Agana, Luz (author)
Riby, Jacques (author)
Liu, Jianjun (author)
Adami, Hans-OlovKarolinska Institutet (author)
Darabi, HatefKarolinska Institutet (author)
Hjalgrim, Henrik (author)
Low, Hui-Qi (author)
Humphreys, KeithKarolinska Institutet (author)
Melbye, Mads (author)
Chang, Ellen T. (author)
Glimelius, BengtKarolinska Institutet,Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi(Swepub:uu)bengglim (author)
Cozen, Wendy (author)
Davis, Scott (author)
Hartge, Patricia (author)
Morton, Lindsay M. (author)
Schenk, Maryjean (author)
Wang, Sophia S. (author)
Armstrong, Bruce (author)
Kricker, Anne (author)
Milliken, Sam (author)
Purdue, Mark P. (author)
Vajdic, Claire M. (author)
Boyle, Peter (author)
Lan, Qing (author)
Zahm, Shelia H. (author)
Zhang, Yawei (author)
Zheng, Tongzhang (author)
Becker, Nikolaus (author)
Benavente, Yolanda (author)
Boffetta, Paolo (author)
Brennan, Paul (author)
Butterbach, Katja (author)
Cocco, Pierluigi (author)
Foretova, Lenka (author)
Maynadie, Marc (author)
de Sanjose, Silvia (author)
Staines, Anthony (author)
Spinelli, John J. (author)
Achenbach, Sara J. (author)
Call, Timothy G. (author)
Camp, Nicola J. (author)
Glenn, Martha (author)
Caporaso, Neil E. (author)
Cerhan, James R. (author)
Cunningham, Julie M. (author)
Goldin, Lynn R. (author)
Hanson, Curtis A. (author)
Kay, Neil E. (author)
Lanasa, Mark C. (author)
Leis, Jose F. (author)
Marti, Gerald E. (author)
Rabe, Kari G. (author)
Rassenti, Laura Z. (author)
Spector, Logan G. (author)
Strom, Sara S. (author)
Vachon, Celine M. (author)
Weinberg, J. Brice (author)
Holly, Elizabeth A. (author)
Chanock, Stephen (author)
Smith, Martyn T. (author)
Bracci, Paige M. (author)
Skibola, Christine F. (author)
Karolinska InstitutetInstitutionen för onkologi, radiologi och klinisk immunologi (creator_code:org_t)

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In:Nature Genetics: Springer Science and Business Media LLC42:8, s. 661-6641061-40361546-1718

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By the author/editor: Conde, Lucia; Halperin, Eran; Akers, Nicholas ...; Brown, Kevin M.; Smedby, Karin E.; Rothman, Nathani ...; show more...; Nieters, Alexand ...; Slager, Susan L.; Brooks-Wilson, A ...; Agana, Luz; Riby, Jacques; Liu, Jianjun; Adami, Hans-Olov; Darabi, Hatef; Hjalgrim, Henrik; Low, Hui-Qi; Humphreys, Keith; Melbye, Mads; Chang, Ellen T.; Glimelius, Bengt; Cozen, Wendy; Davis, Scott; Hartge, Patricia; Morton, Lindsay ...; Schenk, Maryjean; Wang, Sophia S.; Armstrong, Bruce; Kricker, Anne; Milliken, Sam; Purdue, Mark P.; Vajdic, Claire M ...; Boyle, Peter; Lan, Qing; Zahm, Shelia H.; Zhang, Yawei; Zheng, Tongzhang; Becker, Nikolaus; Benavente, Yolan ...; Boffetta, Paolo; Brennan, Paul; Butterbach, Katj ...; Cocco, Pierluigi; Foretova, Lenka; Maynadie, Marc; de Sanjose, Silv ...; Staines, Anthony; Spinelli, John J ...; Achenbach, Sara ...; Call, Timothy G.; Camp, Nicola J.; Glenn, Martha; Caporaso, Neil E ...; Cerhan, James R.; Cunningham, Juli ...; Goldin, Lynn R.; Hanson, Curtis A ...; Kay, Neil E.; Lanasa, Mark C.; Leis, Jose F.; Marti, Gerald E.; Rabe, Kari G.; Rassenti, Laura ...; Spector, Logan G ...; Strom, Sara S.; Vachon, Celine M ...; Weinberg, J. Bri ...; Holly, Elizabeth ...; Chanock, Stephen; Smith, Martyn T.; Bracci, Paige M.; Skibola, Christi ...; show less...

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