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Plasmid-mediated qu...
Plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in Escherichia coli and Klebsiella spp. from Norway and Sweden
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Karah, Nabil (författare)
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Poirel, Laurent (författare)
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Bengtsson, Stina (författare)
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- Sundqvist, Martin (författare)
- Uppsala universitet,Infektionssjukdomar
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- Kahlmeter, Gunnar (författare)
- Uppsala universitet,Klinisk bakteriologi
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Nordmann, Patrice (författare)
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Sundsfjord, Arnfinn (författare)
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Samuelsen, Ørjan (författare)
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(creator_code:org_t)
- Elsevier BV, 2010
- 2010
- Engelska.
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Ingår i: Diagnostic microbiology and infectious disease. - : Elsevier BV. - 0732-8893 .- 1879-0070. ; 66:4, s. 425-431
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The prevalence of the plasmid-mediated quinolone resistance genes qnr and aac(6')-Ib-cr was investigated among clinical isolates of Escherichia coli and Klebsiella spp. selected from 2 collections of consecutive isolates collected in 2004 to 2005 in Norway (n = 2479) and Sweden (n = 2980) and 1 group of extended-spectrum beta-lactamase (ESBL)-producing isolates collected in 2003 in Norway (n = 71). A total of 414 isolates was selected for screening based on resistance to nalidixic acid and/or reduced susceptibility/resistance to ciprofloxacin. The prevalence of both qnr and aac(6')-Ib-cr was higher among the ESBL producers (9.1% and 52.3%, respectively) than in the consecutive isolates (1.1% and 3.2%, respectively). qnrS1 was detected in 6 isolates, whereas qnrB1 and qnrB7 were detected in 2 isolates. The genetic structure surrounding qnrS1 was similar to previously described structures. In 2 isolates, qnrS1 was located on conjugative IncN-type plasmids of approximately 140 kb.
Nyckelord
- aac(6′)-Ib-cr
- Consecutive isolates
- Enterobacteriaceae
- ESBL
- LAP-2
- Plasmid-mediated quinolone resistance
- qnr
- Replicon typing
- S1 nuclease
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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