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Silicone adhesive multilayer foam dressings as adjuvant prophylactic therapy to prevent hospital-acquired pressure ulcers : a pragmatic non-commercial multicentre randomised open label parallel group medical device trial
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- Beeckman, Dimitri, Visiting Professor, 1982- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper,Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium; School of Nursing & Midwifery, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland
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- Fourie, A. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- Raepsaet, C. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- Van Damme, N. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- Manderlier, B. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- De Meyer, D. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- Beele, H. (författare)
- Wound Care Centre, Ghent University, Belgium
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- Smet, S. (författare)
- Wound Care Centre, Ghent University, Belgium
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- Demarré, L. (författare)
- AZ Sint-Elisabeth, Zottegem, Oost-Vlaanderan, Belgium
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- Vossaert, R. (författare)
- AZ Sint-Elisabeth, Zottegem, Oost-Vlaanderan, Belgium
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- de Graaf, A. (författare)
- Wound Care Support Team, Nursing Centre of Excellence, University Hospitals of Leuven, Belgium
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- Verhaeghe, L. (författare)
- AZ Maria Middelares, Ghent, Belgium
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- Vandergheynst, N. (författare)
- AZ Maria Middelares, Ghent, Belgium
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- Hendrickx, B. (författare)
- University Hospital of Brussel (UZB), Department of Plastic Surgery, Brussel, Belgium
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- Hanssens, V. (författare)
- University Hospital of Brussel (UZB), Department of Plastic Surgery, Brussel, Belgium
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- Keymeulen, H. (författare)
- OLV Ziekenhuis Aalst, Aalst, Oost-Vlaanderan, Belgium
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- Vanderwee, K. (författare)
- OLV van Lourdes Ziekenhuis Waregem, Waregem, West-Vlaanderan, Belgium
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- Van De Woestijne, J. (författare)
- AZ Groeninge, Kortrijk, West-Vlaanderan, Belgium
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- Verhaeghe, S. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- Van Hecke, A. (författare)
- Skin Integrity Research Group (SKINT), University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium
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- Savoye, I. (författare)
- Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium
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- Harrison, J. (författare)
- Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium
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- Vrijens, F. (författare)
- Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium
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- Hulstaert, F. (författare)
- Belgian Health Care Knowledge Centre (KCE), Brussels, Belgium
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(creator_code:org_t)
- 2020-12-28
- 2021
- Engelska.
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Ingår i: British Journal of Dermatology. - : Blackwell Science Ltd.. - 0007-0963 .- 1365-2133. ; 185:1, s. 52-61
- Relaterad länk:
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https://doi.org/10.1...
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- BACKGROUND: Silicone adhesive multilayer foam dressings are used as adjuvant therapy to prevent hospital-acquired pressure ulcers (PUs).OBJECTIVES: Determine if silicone foam dressings in addition to standard prevention reduce PU incidence category 2 or worse compared to standard prevention alone.METHODS: Multicentre, randomised controlled, medical device trial conducted in eight Belgian hospitals. At risk adult patients were centrally randomised (n=1633) to study groups based on a 1:1:1 allocation: experimental group 1 (n=542) and 2 (n=545) - pooled as the treatment group - and the control group (n=546). Experimental groups received PU prevention according to hospital protocol, and a silicone foam dressing on these body sites. The control group received standard of care. The primary endpoint was the incidence of a new PU category 2 or worse at these body sites.RESULTS: In the intention-to-treat population (n=1605); 4.0% of patients developed PUs category 2 or worse in the treatment group and 6.3% in the control group (RR=0.64, 95% CI 0.41 to 0.99, P=0.04). Sacral PUs were observed in 2.8% and 4.8% of the patients in the treatment group and the control group, respectively (RR=0.59, 95% CI 0.35 to 0.98, P=0.04). Heel PUs occurred in 1.4% and 1.9% of patients in the treatment and control group respectively (RR=0.76, 95% CI 0.34 to 1.68, P=0.49).CONCLUSIONS: Silicone foam dressings reduce the incidence of PUs category 2 or worse in hospitalised at-risk patients when used in addition to standard of care. Results show a decrease for sacrum, but no statistical difference for heel/trochanter areas.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
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Till lärosätets databas
- Av författaren/redakt...
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Beeckman, Dimitr ...
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Fourie, A.
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Raepsaet, C.
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Van Damme, N.
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Manderlier, B.
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De Meyer, D.
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visa fler...
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Beele, H.
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Smet, S.
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Demarré, L.
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Vossaert, R.
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de Graaf, A.
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Verhaeghe, L.
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Vandergheynst, N ...
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Hendrickx, B.
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Hanssens, V.
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Keymeulen, H.
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Vanderwee, K.
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Van De Woestijne ...
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Verhaeghe, S.
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Van Hecke, A.
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Savoye, I.
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Harrison, J.
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Vrijens, F.
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Hulstaert, F.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Dermatologi och ...
- Artiklar i publikationen
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British Journal ...
- Av lärosätet
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Örebro universitet