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Antidepressant medi...
Antidepressant medication prevents suicide in depression
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- Isacsson, G. (author)
- Karolinska University Hospital, Sweden
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- Reutfors, J. (author)
- Karolinska Institute, Sweden
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- Papadopoulos, Fotios C. (author)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset,University Uppsala Hospital, Sweden
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- Ösby, U. (author)
- Karolinska University Hospital, Sweden
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- Ahlner, Johan (author)
- Linköpings universitet,Klinisk farmakologi,Hälsouniversitetet
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(creator_code:org_t)
- 2010-11-05
- 2010
- English.
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In: Acta Psychiatrica Scandinavica. - : Wiley. - 0001-690X .- 1600-0447. ; 122:6, s. 454-460
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Abstract
Subject headings
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- Objective: Ecological studies have demonstrated a substantial decrease in suicide in parallel with an increasing use of antidepressants. To investigate on the individual level the hypothesis that antidepressant medication was a causal factor. Method: Data on the toxicological detection of antidepressants in 18 922 suicides in Sweden 1992-2003 were linked to registers of psychiatric hospitalization as well as registers with sociodemographic data. Results: The probability for the toxicological detection of an antidepressant was lowest in the non-suicide controls, higher in suicides, and even higher in suicides that had been psychiatric inpatients but excluding those who had been in-patients for the treatment of depression. Conclusion: The finding that in-patient care for depression did not increase the probability of the detection of antidepressants in suicides is difficult to explain other than by the assumption that a substantial number of depressed individuals were saved from suicide by postdischarge treatment with antidepressant medication.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- suicide
- prevention
- depression
- antidepressants
- Psychiatry
- Psykiatri
- MEDICINE
Publication and Content Type
- ref (subject category)
- art (subject category)
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