Lung transplantation in patients with cystic fibrosis and Mycobacterium abscessus infection

Mycobacterium abscessus lung disease is difficult to treat and has been considered a strong relative contraindication to lung transplantation. We performed double lung transplantation in three cystic fibrosis patients with ongoing, and a fourth with recent treatment for Mycobacterium abscessus lung infection. Despite prolonged antibiotic courses and adjustment of immunosuppressive therapy the first three patients developed skin infection and abscesses. At follow-up after 1, 3, 5 and 7 years respectively no patient had evidence of M abscessus infection and all had stable lung function. Lung transplantation in patients with M abscessus lung infection is feasible but may involve severe complications.

Schersten, Henrik (author)
Silverborn, Martin (author)
Jonsson, Bodil (author)
Hollsing, Annika,1949-Uppsala universitet,Institutionen för kvinnors och barns hälsa,Allmänpediatrisk forskning/Nordvall(Swepub:uu)annho840 (author)
Uppsala universitetInstitutionen för kvinnors och barns hälsa (creator_code:org_t)

By the author/editor: Gilljam, Marita; Schersten, Henri ...; Silverborn, Mart ...; Jonsson, Bodil; Hollsing, Annika ...

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