Sökning: onr:"swepub:oai:DiVA.org:uu-148288" > Genome sequence and...
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000 | 07048naa a2201525 4500 | |
001 | oai:DiVA.org:uu-148288 | |
003 | SwePub | |
008 | 110304s2009 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:kth-18764 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1482882 URI |
024 | 7 | a https://doi.org/10.1038/nature083582 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-187642 URI |
040 | a (SwePub)uud (SwePub)kth | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Haas, Brian J.4 aut |
245 | 1 0 | a Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans |
264 | c 2009-09-09 | |
264 | 1 | b Springer Science and Business Media LLC,c 2009 |
338 | a print2 rdacarrier | |
500 | a QC 20100525 | |
520 | a Phytophthora infestans is the most destructive pathogen of potato and a model organism for the oomycetes, a distinct lineage of fungus-like eukaryotes that are related to organisms such as brown algae and diatoms. As the agent of the Irish potato famine in the mid-nineteenth century, P. infestans has had a tremendous effect on human history, resulting in famine and population displacement(1). To this day, it affects world agriculture by causing the most destructive disease of potato, the fourth largest food crop and a critical alternative to the major cereal crops for feeding the world's population(1). Current annual worldwide potato crop losses due to late blight are conservatively estimated at $6.7 billion(2). Management of this devastating pathogen is challenged by its remarkable speed of adaptation to control strategies such as genetically resistant cultivars(3,4). Here we report the sequence of the P. infestans genome, which at similar to 240 megabases (Mb) is by far the largest and most complex genome sequenced so far in the chromalveolates. Its expansion results from a proliferation of repetitive DNA accounting for similar to 74% of the genome. Comparison with two other Phytophthora genomes showed rapid turnover and extensive expansion of specific families of secreted disease effector proteins, including many genes that are induced during infection or are predicted to have activities that alter host physiology. These fast-evolving effector genes are localized to highly dynamic and expanded regions of the P. infestans genome. This probably plays a crucial part in the rapid adaptability of the pathogen to host plants and underpins its evolutionary potential. | |
650 | 7 | a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng |
653 | a Biology | |
653 | a Biologi | |
653 | a effector proteins | |
700 | 1 | a Kamoun, Sophien4 aut |
700 | 1 | a Zody, Michael C.u Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi4 aut0 (Swepub:uu)miczo266 |
700 | 1 | a Jiang, Rays H. Y.4 aut |
700 | 1 | a Handsaker, Robert E.4 aut |
700 | 1 | a Cano, Liliana M.4 aut |
700 | 1 | a Grabherr, Manfred4 aut |
700 | 1 | a Kodira, Chinnappa D.4 aut |
700 | 1 | a Raffaele, Sylvain4 aut |
700 | 1 | a Torto-Alalibo, Trudy4 aut |
700 | 1 | a Bozkurt, Tolga O.4 aut |
700 | 1 | a Ah-Fong, Audrey M. V.4 aut |
700 | 1 | a Alvarado, Lucia4 aut |
700 | 1 | a Anderson, Vicky L.4 aut |
700 | 1 | a Armstrong, Miles R.4 aut |
700 | 1 | a Avrova, Anna4 aut |
700 | 1 | a Baxter, Laura4 aut |
700 | 1 | a Beynon, Jim4 aut |
700 | 1 | a Boevink, Petra C.4 aut |
700 | 1 | a Bollmann, Stephanie R.4 aut |
700 | 1 | a Bos, Jorunn I. B.4 aut |
700 | 1 | a Bulone, Vincentu KTH,Glykovetenskap4 aut0 (Swepub:kth)u13o1auq |
700 | 1 | a Cai, Guohong4 aut |
700 | 1 | a Cakir, Cahid4 aut |
700 | 1 | a Carrington, James C.4 aut |
700 | 1 | a Chawner, Megan4 aut |
700 | 1 | a Conti, Lucio4 aut |
700 | 1 | a Costanzo, Stefano4 aut |
700 | 1 | a Ewan, Richard4 aut |
700 | 1 | a Fahlgren, Noah4 aut |
700 | 1 | a Fischbach, Michael A.4 aut |
700 | 1 | a Fugelstad, Johannau KTH,Glykovetenskap4 aut0 (Swepub:kth)u19ifqej |
700 | 1 | a Gilroy, Eleanor M.4 aut |
700 | 1 | a Gnerre, Sante4 aut |
700 | 1 | a Green, Pamela J.4 aut |
700 | 1 | a Grenville-Briggs, Laura J.4 aut |
700 | 1 | a Griffith, John4 aut |
700 | 1 | a Gruenwald, Niklaus J.4 aut |
700 | 1 | a Horn, Karolyn4 aut |
700 | 1 | a Horner, Neil R.4 aut |
700 | 1 | a Hu, Chia-Hui4 aut |
700 | 1 | a Huitema, Edgar4 aut |
700 | 1 | a Jeong, Dong-Hoon4 aut |
700 | 1 | a Jones, Alexandra M. E.4 aut |
700 | 1 | a Jones, Jonathan D. G.4 aut |
700 | 1 | a Jones, Richard W.4 aut |
700 | 1 | a Karlsson, Elinor K.4 aut |
700 | 1 | a Kunjeti, Sridhara G.4 aut |
700 | 1 | a Lamour, Kurt4 aut |
700 | 1 | a Liu, Zhenyu4 aut |
700 | 1 | a Ma, LiJun4 aut |
700 | 1 | a MacLean, Daniel4 aut |
700 | 1 | a Chibucos, Marcus C.4 aut |
700 | 1 | a McDonald, Hayes4 aut |
700 | 1 | a McWalters, Jessica4 aut |
700 | 1 | a Meijer, Harold J. G.4 aut |
700 | 1 | a Morgan, William4 aut |
700 | 1 | a Morris, Paul F.4 aut |
700 | 1 | a Munro, Carol A.4 aut |
700 | 1 | a O'Neill, Keith4 aut |
700 | 1 | a Ospina-Giraldo, Manuel4 aut |
700 | 1 | a Pinzon, Andres4 aut |
700 | 1 | a Pritchard, Leighton4 aut |
700 | 1 | a Ramsahoye, Bernard4 aut |
700 | 1 | a Ren, Qinghu4 aut |
700 | 1 | a Restrepo, Silvia4 aut |
700 | 1 | a Roy, Sourav4 aut |
700 | 1 | a Sadanandom, Ari4 aut |
700 | 1 | a Savidor, Alon4 aut |
700 | 1 | a Schornack, Sebastian4 aut |
700 | 1 | a Schwartz, David C.4 aut |
700 | 1 | a Schumann, Ulrike D.4 aut |
700 | 1 | a Schwessinger, Ben4 aut |
700 | 1 | a Seyer, Lauren4 aut |
700 | 1 | a Sharpe, Ted4 aut |
700 | 1 | a Silvar, Cristina4 aut |
700 | 1 | a Song, Jing4 aut |
700 | 1 | a Studholme, David J.4 aut |
700 | 1 | a Sykes, Sean4 aut |
700 | 1 | a Thines, Marco4 aut |
700 | 1 | a van de Vondervoort, Peter J. I.4 aut |
700 | 1 | a Phuntumart, Vipaporn4 aut |
700 | 1 | a Wawra, Stephan4 aut |
700 | 1 | a Weide, Rob4 aut |
700 | 1 | a Win, Joe4 aut |
700 | 1 | a Young, Carolyn4 aut |
700 | 1 | a Zhou, Shiguo4 aut |
700 | 1 | a Fry, William4 aut |
700 | 1 | a Meyers, Blake C.4 aut |
700 | 1 | a van West, Pieter4 aut |
700 | 1 | a Ristaino, Jean4 aut |
700 | 1 | a Govers, Francine4 aut |
700 | 1 | a Birch, Paul R. J.4 aut |
700 | 1 | a Whisson, Stephen C.4 aut |
700 | 1 | a Judelson, Howard S.4 aut |
700 | 1 | a Nusbaum, Chad4 aut |
710 | 2 | a Uppsala universitetb Institutionen för medicinsk biokemi och mikrobiologi4 org |
773 | 0 | t Natured : Springer Science and Business Media LLCg 461:7262, s. 393-398q 461:7262<393-398x 0028-0836x 1476-4687 |
856 | 4 | u https://www.nature.com/articles/nature08358.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-148288 |
856 | 4 8 | u https://doi.org/10.1038/nature08358 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-18764 |
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