Medical proton dosimetry using radioluminescence from aluminium oxide crystals attached to optical-fiber cables

The prime objective of this study is to investigate if radioluminescence (RL) from carbon-doped aluminum oxide (Al2O3:C) crystals potentially can be used for absorbed dose-rate measurements during proton radiotherapy. The RL from two separate (2 mg) Al2O3:C crystals attached to optical-fiber cables were recorded during irradiations in water in a 175 MeV clinical proton beam. The RL response for low-LET protons in the plateau region of the Bragg curve was found to closely resemble that observed for a clinical 6 MV X-ray beam. An identical response was found in the Bragg peak (where the dose-averaged LET is about 4 keV/mu m) for absorbed doses less than 0.3 Gy. For doses in the range of 0.3-3Gy, we observed a significant decrease in luminescence efficiency with LET. At 3 Gy, the luminescence efficiency was about 60% in the Bragg-peak region. The study implies that the RL-signal from Al2O3:C could potentially be suitable for medical proton dosimetry in the 0-0.3 Gy range even without any LET-dependent correction factors.

NATURVETENSKAP Fysik Acceleratorfysik och instrumentering hsv//swe
NATURAL SCIENCES Physical Sciences Accelerator Physics and Instrumentation hsv//eng
radiation-induced luminescence
dosimetry
neutron and proton
MEDICINE
MEDICIN
radiation-induced luminescence
dosimetry
neutron and proton

Medin, JoakimLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)rfa-jme (författare)
Medin, J. (författare)
Grusell, ErikUppsala universitet,Avdelningen för sjukhusfysik (författare)
Jain, M. (författare)
Mattsson, SörenLund University,Lunds universitet,Medicinsk strålningsfysik, Malmö,Forskargrupper vid Lunds universitet,Medical Radiation Physics, Malmö,Lund University Research Groups(Swepub:lu)rfa-sma (författare)
Medicinsk strålningsfysik, MalmöForskargrupper vid Lunds universitet (creator_code:org_t)

Ingår i:Nuclear Instruments and Methods in Physics Research Section A: Elsevier BV580:1, s. 466-4680168-90021872-95760167-5087

Av författaren/redakt...: Andersen, C. E.; Medin, Joakim; Medin, J.; Grusell, Erik; Jain, M.; Mattsson, Sören

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