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One-year outcomes after transcatheter aortic valve implantation with the latest-generation SAPIEN balloonexpandable valve : the S3U registry

Cannata, Stefano (författare)
IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy.
Gandolfo, Caterina (författare)
IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy.
Ribichini, Flavio (författare)
Univ Verona, Div Cardiol, Dept Med, Verona, Italy.
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Van Mieghem, Nicolas (författare)
Erasmus Univ, Dept Cardiol, Ctr Thorax, Med Ctr, Rotterdam, Netherlands.
Buccheri, Sergio (författare)
Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Institutionen för medicinska vetenskaper
Barbanti, Marco (författare)
AOU Policlin G Rodolico San Marco, Div Cardiol, Catania, Italy.
Berti, Sergio (författare)
Fdn CNR Reg Toscana G Monasterio, UOC Cardiol Diagnost & Interventist, Massa, Italy.
Teles, Rui Campante (författare)
Hosp Santa Cruz, Nova Med Sch, CHLO, CEDOC, Lisbon, Portugal.
Bartorelli, Antonio L. (författare)
Univ Milan, Ctr Cardiol Monzino IRCCS, Milan, Italy.
Musumeci, Giuseppe (författare)
Mauriziano Hosp, Dept Cardiol, Turin, Italy.
Piva, Tommaso (författare)
Osped Riuniti Ancona, Intervent Cardiol, Ancona, Italy.
Nombela-Franco, Luis (författare)
Hosp Clin San Carlos, Cardiovasc Inst, Inst Invest Sanitaria San Carlos, Madrid, Spain.
La Spina, Ketty (författare)
IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy.
Palmerini, Tullio (författare)
IRCCS Univ Hosp Bologna, Cardio Thorac Vasc Dept, Cardiol Unit, Policlin S Orsola, Bologna, Italy.
Adrichem, Rik (författare)
Erasmus Univ, Dept Cardiol, Ctr Thorax, Med Ctr, Rotterdam, Netherlands.;Uppsala Univ Hosp, Dept Med Sci, Uppsala, Sweden.
Esposito, Augusto (författare)
Fdn CNR Reg Toscana G Monasterio, UOC Cardiol Diagnost & Interventist, Massa, Italy.
Lopes, Pedro (författare)
Hosp Santa Cruz, Nova Med Sch, CHLO, CEDOC, Lisbon, Portugal.
Olivares, Paolo (författare)
Univ Milan, Ctr Cardiol Monzino IRCCS, Milan, Italy.
Annibali, Gianmarco (författare)
Mauriziano Hosp, Dept Cardiol, Turin, Italy.
Nicolini, Elisa (författare)
Osped Riuniti Ancona, Intervent Cardiol, Ancona, Italy.
Marroquin, Luis (författare)
Hosp Clin San Carlos, Cardiovasc Inst, Inst Invest Sanitaria San Carlos, Madrid, Spain.
Tamburino, Corrado (författare)
Fdn CNR Reg Toscana G Monasterio, UOC Cardiol Diagnost & Interventist, Massa, Italy.
Tarantini, Giuseppe (författare)
Univ Padua, Dept Cardiac Thorac Vasc Sci & Publ Hlth, Intervent Cardiol Unit, Padua, Italy.
Saia, Francesco (författare)
IRCCS Univ Hosp Bologna, Cardio Thorac Vasc Dept, Cardiol Unit, Policlin S Orsola, Bologna, Italy.
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IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy Univ Verona, Div Cardiol, Dept Med, Verona, Italy. (creator_code:org_t)
Europa Digital & Publishing, 2023
2023
Engelska.
Ingår i: EuroIntervention. - : Europa Digital & Publishing. - 1774-024X .- 1969-6213. ; 18:17, s. 1418-
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.4...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: Initial data about the performance of the new-generation SAPIEN 3 Ultra (S3U) valve are highly promising. However, evidence about the longer-term performance and safety of the S3U is scarce.Aims: We aimed to investigate the 1-year clinical and echocardiographic outcomes of transcatheter aortic valve implantation (TAVI) using the S3U compared with its predecessor, the SAPIEN 3 valve (S3).Methods: The SAPIEN 3 Ultra registry included consecutive patients who underwent transfemoral TAVI at 12 European centres with the S3U or S3 between October 2016 and December 2020. One-to-one propensity score (PS) matching was performed to account for differences in baseline characteristics. The primary outcomes of interest were all-cause death and the composite of all-cause death, disabling stroke and hospitalisation for heart failure at 1 year.Results: The overall study cohort encompassed 1,692 patients treated with either the S3U (n=519) or S3 (n=1,173). The PS-matched population had a total of 992 patients (496 per group). At 1 year, the rate of death from any cause was 4.9% in the S3U group and 6.3% in the S3 group (p=0.743). Similarly, there were no significant differences in the rates of the primary composite outcome (9.5% in the S3 group and 6.6% in the S3U group; p=0.162). The S3U was associated with lower rates of mild paravalvular leak (PVL) compared with the S3 (odds ratio 0.63, 95% confidence interval: 0.44 to 0.88; p<0.01). No significant differences in transprosthetic gradients were observed between the two groups.Conclusions: Compared with the S3, the S3U transcatheter heart valve was associated with similar 1-year clinical outcomes but reduced rates of mild PVL.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

femoral
miscellaneous
paravalvular leak
TAVI
transthoracic echocardiogram

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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