Three-year results of a randomized clinical trial of lightweight or standard polypropylene mesh in Lichtenstein repair of primary inguinal hernia

Background: This randomized trial examined whether lightweight (LW) polypropylene mesh (large pore size, partially absorbable) could have long-term benefits in reducing chronic pain and inflammation after inguinal hernia repair. Methods: Six hundred men with a primary unilateral inguinal hernia were randomized to Lichtenstein repair using a standard polypropylene mesh or a LW mesh in one of six centres. The patients were blinded to which mesh they received. Clinical examination was performed and a pain questionnaire completed 3 years after surgery. Results: Of the 590 men who had surgery, 243 (82.7 percent) of 294 in the standard mesh group and 251 (84.8 per cent) of 296 in the LW mesh group were examined in the clinic, a median of 37 (range 30-48) months after hernia repair. There were nine recurrent hernias in each group (3.7 per cent with standard mesh and 3.6 per cent with LW mesh). Patients who had LW mesh had less pain on examination, less pain on rising from lying to sitting, fewer miscellaneous groin problems and felt the mesh less often than patients with standard mesh. Conclusion: Use of LW mesh for Lichtenstein hernia repair did not affect recurrence rates, but improved some aspects of pain and discomfort 3 years after surgery.

Wollert, StaffanUppsala universitet,Institutionen för kirurgiska vetenskaper (author)
Österberg, J. (author)
Smedberg, S. (author)
Granlund, H. (author)
Heikkinen, T. -J (author)
Karolinska InstitutetInstitutionen för kirurgiska vetenskaper (creator_code:org_t)

In:British Journal of Surgery: Oxford University Press (OUP)93:9, s. 1056-10590007-13231365-2168

By the author/editor: Bringman, S.; Wollert, Staffan; Österberg, J.; Smedberg, S.; Granlund, H.; Heikkinen, T. -J

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