Sequence types and plasmid carriage of uropathogenic Escherichia coli devoid of phenotypically detectable resistance

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Kahlmeter Gunnar) > Sequence types and ...

Details
MARC

Bengtsson, Stina (author)

Sequence types and plasmid carriage of uropathogenic Escherichia coli devoid of phenotypically detectable resistance

Article/chapterEnglish2012

Publisher, publication year, extent ...

2011-10-06
Oxford University Press (OUP),2012
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:uu-164699
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-164699URI
https://doi.org/10.1093/jac/dkr421DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Objectives Plasmids play a major role in the dissemination of antibiotic resistance, and several studies have shown the association between specific resistance mechanisms and certain plasmid types and/or Escherichia coli lineages. This study describes the distribution of plasmids, replicon types, sequence types (STs) and ST complexes (STCs) of E. coli devoid of phenotypic resistance to 24 antibiotics. Methods Eighty E. coli isolates from urinary tract infections from four European countries were selected because of their lack of phenotypically detectable antibiotic resistance. The isolates were characterized to the phylogenetic group level using PCR and to ST by multilocus sequence typing. Plasmid carriage was assessed using S1 nuclease PFGE profiling and PCR-based replicon typing. Results Plasmids were detected in only 38/80 (47%) of the isolates; one (n = 18), two (n = 14), three (n = 5) and four (n = 1) plasmids. Six different replicon types were identified, the most common being a combination of IncFII and IncFIB. Most isolates belonged to phylogenetic group B2 and STC73 (n = 20), STC95 (n = 7) and ST420 (n = 6). A high proportion of STC73 isolates (75%) was devoid of plasmids. No association could be found between specific STs and replicon type. Conclusions A large proportion of E. coli strains phenotypically devoid of antibiotic resistance were plasmid naive. Those isolates that harboured plasmids displayed replicon types similar to those of resistant isolates, but the distributions of STs and STCs were different. This may indicate chromosomally encoded mechanisms important for the stabilization of plasmids harbouring antibiotic resistance.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng

Added entries (persons, corporate bodies, meetings, titles ...)

Naseer, Umaer (author)
Sundsfjord, Arnfinn (author)
Kahlmeter, GunnarUppsala universitet,Klinisk bakteriologi(Swepub:uu)gunka977 (author)
Sundqvist, MartinUppsala universitet,Infektionssjukdomar(Swepub:uu)marsu620 (author)
Uppsala universitetKlinisk bakteriologi (creator_code:org_t)

Related titles

In:Journal of Antimicrobial Chemotherapy: Oxford University Press (OUP)67:1, s. 69-730305-74531460-2091

Internet link

Find in a library

Journal of Antimicrobial Chemotherapy (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Bengtsson, Stina; Naseer, Umaer; Sundsfjord, Arnf ...; Kahlmeter, Gunna ...; Sundqvist, Marti ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...

Articles in the publication: Journal of Antim ...

By the university: Uppsala University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se