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- Korsgren, OlleUppsala universitet,Enheten för klinisk immunologi (author)
Optimising islet engraftment is critical for successful clinical islet transplantation
- Article/chapterEnglish2008
Publisher, publication year, extent ...
- 2007-11-27
- Springer Science and Business Media LLC,2008
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-16835
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-16835URI
- https://doi.org/10.1007/s00125-007-0868-9DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:116339970URI
- https://lup.lub.lu.se/record/1200293URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Clinical islet transplantation is currently being explored as a treatment for persons with type 1 diabetes and hypoglycaemia unawareness. Although 'proof-of-principle' has been established in recent clinical studies, the procedure suffers from low efficacy. At the time of transplantation, the isolated islets are allowed to embolise the liver after injection in the portal vein, a procedure that is unique in the area of transplantation. A novel view on the engraftment of intraportally transplanted islets is presented that could explain the low efficacy of the procedure.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Endokrinologi och diabetes hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Endocrinology and Diabetes hsv//eng
- Clinical
- Engraftment
- Innate immunity
- Intraportal
- Intramuscular
- Islet transplantation
- Liver morphology
- Thrombosis
- Tumour metastasis
- Revascularisation
- MEDICINE
- MEDICIN
- tumour metastasis
- revascularisation
- thrombosis
- liver morphology
- islet transplantation
- intramuscular
- intraportal
- innate immunity
- clinical
- engraftment
Added entries (persons, corporate bodies, meetings, titles ...)
- Lundgren, TorbjörnKarolinska Institutet (author)
- Felldin, Marie (author)
- Foss, Aksel (author)
- Isaksson, B.Karolinska Institutet (author)
- Permert, JohanKarolinska Institutet (author)
- Persson, N HLund University,Lunds universitet,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)extLU-124 (author)
- Rafael, E. (author)
- Rydén, M.Karolinska Institutet (author)
- Salmela, Kaija (author)
- Tibell, AnnikaKarolinska Institutet (author)
- Tufveson, GunnarUppsala universitet,Transplantationskirurgi(Swepub:uu)gutuf839 (author)
- Nilsson, BoUppsala universitet,Enheten för klinisk immunologi(Swepub:uu)bonils (author)
- Uppsala universitetEnheten för klinisk immunologi (creator_code:org_t)
Related titles
- In:Diabetologia: Springer Science and Business Media LLC51:2, s. 227-320012-186X1432-0428
Internet link
- https://link.springer.com/content/pdf/10.1007%2Fs00125-007-0868-9.pdf
- http://dx.doi.org/10.1007/s00125-007-0868-9FULLTEXT
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-16835
- https://doi.org/10.1007/s00125-007-0868-9
- http://kipublications.ki.se/Default.aspx?queryparsed=id:116339970
- https://lup.lub.lu.se/record/1200293
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