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Multidisciplinary t...
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Glimelius, BengtUppsala universitet,Enheten för onkologi
(författare)
Multidisciplinary treatment of patients with rectal cancer : Development during the past decades and plans for the future
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
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2012-04-18
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Uppsala Medical Society,2012
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-174365
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-174365URI
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https://doi.org/10.3109/03009734.2012.658974DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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In rectal cancer treatment, both the local primary and the regional and systemic tumour cell deposits must be taken care of in order to improve survival. The three main treatments, surgery, radiotherapy, and chemotherapy, each with their own advantages and limitations, must then be combined to improve results. Several large randomized trials have shown that combinations of the modalities have markedly reduced the loco-regional recurrences, but have not yet had any major influence on overall survival. The best integration of the weakest modality, to date the drugs (conventional cytotoxics and biologicals), is not known. A new generation of trials exploring the best sequence of treatments is required. Furthermore, treatment of rectal cancer is administered to populations of individuals, based upon clinical factors and imaging, and can presently not be further individualized. There is an urgent need to develop response predictors.
Ämnesord och genrebeteckningar
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Chemoradiotherapy
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chemotherapy
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local control
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multidisciplinary
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organ preservation
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radiotherapy
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randomized trials
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rectal cancer
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Uppsala universitetEnheten för onkologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Upsala Journal of Medical Sciences: Uppsala Medical Society117:2, s. 225-2360300-97342000-1967
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