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Evaluation of an im...
Evaluation of an improved method of simulating lung nodules in chest tomosynthesis
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- Svalkvist, Angelica (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiofysik,Institute of Clinical Sciences, Department of Radiation Physics,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Johnsson, Åse (Allansdotter), 1966 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Vikgren, Jenny, 1957 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Hakansson, M. (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiofysik,Institute of Clinical Sciences, Department of Radiation Physics,University of Gothenburg, Sweden
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- Ullman, Gustaf (författare)
- Linköpings universitet,Uppsala universitet,Beräknings- och systembiologi,Medicinsk radiofysik,Hälsouniversitetet
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- Boijsen, Marianne, 1948 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Fisichella, Valeria A, 1974 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Flinck, Agneta, 1953 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiologi,Institute of Clinical Sciences, Department of Radiology,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Molnar, David (författare)
- Sahlgrens University Hospital, Sweden
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- Månsson, Lars Gunnar, 1951 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiofysik,Institute of Clinical Sciences, Department of Radiation Physics,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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- Båth, Magnus, 1974 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för radiofysik,Institute of Clinical Sciences, Department of Radiation Physics,University of Gothenburg, Sweden Sahlgrens University Hospital, Sweden
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(creator_code:org_t)
- 2012-10-01
- 2012
- Engelska.
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Ingår i: Acta Radiologica. - : SAGE Publications. - 0284-1851 .- 1600-0455. ; 53:8, s. 874-884
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://gup.ub.gu.se...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: Simulated pathology is a valuable complement to clinical images in studies aiming at evaluating an imaging technique. In order for a study using simulated pathology to be valid, it is important that the simulated pathology in a realistic way reflect the characteristics of real pathology. Purpose: To perform a thorough evaluation of a nodule simulation method for chest tomosynthesis, comparing the detection rate and appearance of the artificial nodules with those of real nodules in an observer performance experiment. Material and Methods: A cohort consisting of 64 patients, 38 patients with a total of 129 identified pulmonary nodules and 26 patients without identified pulmonary nodules, was used in the study. Simulated nodules, matching the real clinically found pulmonary nodules by size, attenuation, and location, were created and randomly inserted into the tomosynthesis section images of the patients. Three thoracic radiologists and one radiology resident reviewed the images in an observer performance study divided into two parts. The first part included nodule detection and the second part included rating of the visual appearance of the nodules. The results were evaluated using a modified receiver-operating characteristic (ROC) analysis. Results: The sensitivities for real and simulated nodules were comparable, as the area under the modified ROC curve (AUC) was close to 0.5 for all observers (range, 0.43-0.55). Even though the ratings of visual appearance for real and simulated nodules overlapped considerably, the statistical analysis revealed that the observers to were able to separate simulated nodules from real nodules (AUC values range 0.70-0.74). Conclusion: The simulation method can be used to create artificial lung nodules that have similar detectability as real nodules in chest tomosynthesis, although experienced thoracic radiologists may be able to distinguish them from real nodules.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- Adults
- Digital radiography
- Lung
- Observer performance
- Technology assessments
- Thorax
- Artificial organs
- Biological organs
- Diseases
- Pathology
- Radiology
- Visualization
- Tomography
- thorax
- digital radiography
- lung
- adults
- observer performance
- technology assessments
- MEDICINE
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Svalkvist, Angel ...
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Johnsson, Åse (A ...
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Vikgren, Jenny, ...
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Hakansson, M.
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Ullman, Gustaf
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Boijsen, Mariann ...
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Fisichella, Vale ...
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Flinck, Agneta, ...
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Molnar, David
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Månsson, Lars Gu ...
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Båth, Magnus, 19 ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Radiologi och bi ...
- Artiklar i publikationen
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Acta Radiologica
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Uppsala universitet
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Göteborgs universitet
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Linköpings universitet