Modeling of self-controlling hyperthermia based on nickel alloy ferrofluids : Proposition of new nanoparticles

• In order to provide sufficient heat without overheating healthy tissue in magnetic fluid hyperthermia (MFH), a careful design of the magnetic properties of nanoparticles is essential. We perform a systematic calculation of magnetic properties of Ni-alloy nanoparticles. Stoner-Wohlfarth model based theories (SWMBTs) are considered and the linear response theory (LRT) is used to extract the hysteresis loop of nickel alloy nanoparticles in alternating magnetic fields. It is demonstrated that in the safe range of magnetic field intensity and frequency the LRT cannot be used for the calculation of the area in the hysteresis for magnetic fields relevant for hyperthermia. The best composition and particle size for self-controlling hyperthermia with nickel alloys is determined based on SWMBTs. It is concluded that Ni-V and Ni-Zn are good candidates for self-controlling hyperthermia.

Ämnesord

NATURVETENSKAP  -- Fysik (hsv//swe)

NATURAL SCIENCES  -- Physical Sciences (hsv//eng)

Nyckelord

Hyperthermia

Self-controlling

Nickel alloy

Nanoparticle

Modeling

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