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Stool cultures obta...
Stool cultures obtained before liver transplantation are useful for choice of perioperative antibiotic prophylaxis
- Article/chapterEnglish1997
Publisher, publication year, extent ...
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Frontiers Media SA,1997
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-199543
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-199543URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:1962023URI
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https://doi.org/10.1007/s001470050082DOI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Bacterial infections, especially cholangitis, are still common complications after liver transplantation (LTx). During recent years, multiresistant enterococci have become a nosocomial problem in transplant units. The present prospective study on 26 patients, including 24 patients with chronic liver disease, demonstrated that enterococci were the predominant micro-organism involved in post-LTx bacterial infections. They were cultured in the feces and in other sites of 10 out of 13 (77%) patients who underwent extensive examinations. Ampicillin-resistant Enterococcus faecium strains were isolated in urine or feces of 2 of the 13 patients prior to LTx. Similarly, resistance to ampicillin and gentamicin, the empirically used antibiotics for patients with fever of unknown origin, was found in E. faecium strains in 3 and 2 patients, respectively. Moreover, multiresistant E. faecium and E. faecalis strains were demonstrated in 46% of the patients in the postoperative period (3 months). However, no vancomycin-resistant enterococci were isolated. The use of antibiotics within 4 months prior to LTx significantly increased the risk of developing ampicillin-resistant bacteria at the time of LTx and of infections with bacteria of enteric origin after LTx (P = 0.03 and 0.01, respectively). We conclude that stool and urine cultures performed prior to LTX may be useful for selecting prophylactic antibiotic regimens.
Added entries (persons, corporate bodies, meetings, titles ...)
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Andersson, J
(author)
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Ericzon, B GKarolinska Institutet
(author)
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Palmgren, A C
(author)
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Broomé, U
(author)
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Duraj, FransKarolinska Institute, Huddinge University Hospital, Sweden(Swepub:uu)frdur935
(author)
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Bergquist, AKarolinska Institutet
(author)
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Herlenius, G
(author)
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Nord, C EKarolinska Institutet
(author)
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Karolinska InstitutetKarolinska Institute, Huddinge University Hospital, Sweden
(creator_code:org_t)
Related titles
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In:Transplant International: Frontiers Media SA10:6, s. 432-4380934-08741432-2277
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