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  • Abelsson, JohannaKarolinska Institutet (author)

Patients with polycythemia vera have worst impairment of quality of life among patients with newly diagnosed myeloproliferative neoplasms

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • 2013-07-29
  • Informa UK Limited,2013
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-210214
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-210214URI
  • https://doi.org/10.3109/10428194.2013.766732DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:127500421URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • The quality of life (QoL) at the time of diagnosis of myeloproliferative neoplasm (MPN) has, to date, not been studied. One hundred and seventy-nine patients with MPN: 80 with essential thrombocythemia (ET), 73 with polycythemia vera (PV), 22 with primary myelofibrosis (PMF) and four with MPN undifferentiated, were included in this study. European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC-QLQC30) and the MPN-Symptom Assessment Form (MPN-SAF) were used to evaluate QoL. Fatigue was the most reported symptom in these patients. Patients with PV reported significantly higher mean scores for inactivity, dizziness, cough, itching, depression and lower total QoL compared to patients with ET. Patients with PV had significantly more headache and itching compared to patients with PMF. When the newly diagnosed patients with MPN were compared with a cohort of patients with MPN with mean disease duration of 7.8 years, the differences were most striking for patients with PMF, with significantly more fatigue, abdominal discomfort, concentration problems, insomnia, fever, weight loss and lower overall QoL developed over time.

Subject headings and genre

  • Quality of life
  • polycythemia vera
  • essential thrombocythemia
  • primary myelofibrosis

Added entries (persons, corporate bodies, meetings, titles ...)

  • Andreasson, Bjorn (author)
  • Samuelsson, Jan (author)
  • Hultcrantz, MalinKarolinska Institutet (author)
  • Ejerblad, ElisabethUppsala universitet,Hematologi(Swepub:uu)eleje020 (author)
  • Johansson, Berit (author)
  • Emanuel, Robyn (author)
  • Mesa, Ruben (author)
  • Johansson, Peter (author)
  • Karolinska InstitutetHematologi (creator_code:org_t)

Related titles

  • In:Leukemia and Lymphoma: Informa UK Limited54:10, s. 2226-22301042-81941029-2403

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