A fast and reliable approach to cell nuclei segmentation in PAP stained cervical smears

• Fast and reliable segmentation of cervical cellnuclei is one of the crucial steps of an automated screeningsystem that aims early detection of cervical cancer. In thispaper, we propose an edge based approach using custom-ized Laplacian of Gaussian (LoG) filter to segment freelying cell nuclei in bright-field microscope images of Papsmear. The LoG is generally employed as a second orderedge detector in image processing. The images may havethe challenges of inconsistent staining, overlapping andfolded cells. Experimenting proposed method over all typesof cervical images including sufficient number of highgrade lesions of cervical cancer shows that our methodperforms well for stain varied images containing focusednuclei.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Elektroteknik och elektronik -- Signalbehandling (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Electrical Engineering, Electronic Engineering, Information Engineering -- Signal Processing (hsv//eng)

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