High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.

Nyckelord

Acute Disease

Child; Preschool

Chromosome Breakage

Chromosomes; Human; Pair 12

Chromosomes; Human; Pair 7

Cohort Studies

Female

Homeodomain Proteins/*genetics/metabolism

Humans

In Situ Hybridization; Fluorescence

Infant

Infant; Newborn

Leukemia; Lymphocytic; Acute/*genetics

Leukemia; Myeloid/*genetics

Male

Models; Genetic

Oncogene Proteins; Fusion/genetics

Proto-Oncogene Proteins c-ets/genetics

Repressor Proteins/genetics

Research Support; Non-U.S. Gov't

Transcription Factors/*genetics/metabolism

Translocation; Genetic

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)