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Incidence, risk fac...
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Nisula, Sara
(författare)
Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units : the FINNAKI study
- Artikel/kapitelEngelska2013
Förlag, utgivningsår, omfång ...
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2013-01-05
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Springer Science and Business Media LLC,2013
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-216190
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-216190URI
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https://doi.org/10.1007/s00134-012-2796-5DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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PURPOSEWe aimed to determine the incidence, risk factors and outcome of acute kidney injury (AKI) in Finnish ICUs.METHODSThis prospective, observational, multi-centre study comprised adult emergency admissions and elective patients whose stay exceeded 24 h during a 5-month period in 17 Finnish ICUs. We defined AKI first by the Acute Kidney Injury Network (AKIN) criteria supplemented with a baseline creatinine and second with the Kidney Disease: Improving Global Outcomes (KDIGO) criteria. We screened the patients' AKI status and risk factors for up to 5 days.RESULTSWe included 2,901 patients. The incidence (95 % confidence interval) of AKI was 39.3 % (37.5-41.1 %). The incidence was 17.2 % (15.8-18.6 %) for stage 1, 8.0 % (7.0-9.0 %) for stage 2 and 14.1 % (12.8-15.4 %) for stage 3 AKI. Of the 2,901 patients 296 [10.2 % (9.1-11.3 %)] received renal replacement therapy. We received an identical classification with the new KDIGO criteria. The population-based incidence (95 % CI) of ICU-treated AKI was 746 (717-774) per million population per year (reference population: 3,671,143, i.e. 85 % of the Finnish adult population). In logistic regression, pre-ICU hypovolaemia, diuretics, colloids and chronic kidney disease were independent risk factors for AKI. Hospital mortality (95 % CI) for AKI patients was 25.6 % (23.0-28.2 %) and the 90-day mortality for AKI patients was 33.7 % (30.9-36.5 %). All AKIN stages were independently associated with 90-day mortality.CONCLUSIONSThe incidence of AKI in the critically ill in Finland was comparable to previous large multi-centre ICU studies. Hospital mortality (26 %) in AKI patients appeared comparable to or lower than in other studies.
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Kaukonen, Kirsi-Maija
(författare)
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Vaara, Suvi T
(författare)
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Korhonen, Anna-Maija
(författare)
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Poukkanen, Meri
(författare)
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Karlsson, Sari
(författare)
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Haapio, Mikko
(författare)
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Inkinen, Outi
(författare)
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Parviainen, Ilkka
(författare)
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Suojaranta-Ylinen, Raili
(författare)
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Laurila, Jouko J
(författare)
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Tenhunen, JyrkiDepartment of Intensive Care Medicine, Tampere University Hospital, Tampere, Finland(Swepub:uu)jyrte348
(författare)
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Reinikainen, Matti
(författare)
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Ala-Kokko, Tero
(författare)
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Ruokonen, Esko
(författare)
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Kuitunen, Anne
(författare)
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Pettilä, Ville
(författare)
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Department of Intensive Care Medicine, Tampere University Hospital, Tampere, Finland
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Intensive Care Medicine: Springer Science and Business Media LLC39:3, s. 420-4280342-46421432-1238
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Nisula, Sara
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Kaukonen, Kirsi- ...
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Vaara, Suvi T
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Korhonen, Anna-M ...
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Poukkanen, Meri
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Karlsson, Sari
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visa fler...
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Haapio, Mikko
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Inkinen, Outi
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Parviainen, Ilkk ...
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Suojaranta-Yline ...
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Laurila, Jouko J
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Tenhunen, Jyrki
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Reinikainen, Mat ...
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Ala-Kokko, Tero
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Ruokonen, Esko
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Kuitunen, Anne
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Pettilä, Ville
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Intensive Care M ...
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Uppsala universitet