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  • Le Moual, Nicole (author)

Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II

  • Article/chapterEnglish2014

Publisher, publication year, extent ...

  • 2013-08-15
  • European Respiratory Society (ERS),2014
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-220799
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-220799URI
  • https://doi.org/10.1183/09031936.00034913DOI
  • https://gup.ub.gu.se/publication/194978URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Occupational exposure is a well-recognised modifiable risk factor for asthma, but the relationship between occupational exposure and asthma control has not been studied. We aimed to study this association among working-age adults from the European Community Respiratory Health Survey (ECRHS). Data were available for 7077 participants (mean age 43 years, 45% never-smokers, 5867 without asthma and 1210 with current asthma). Associations between occupational exposure to specific asthmagens and asthma control status (33% with uncontrolled asthma, based on the Global Initiative for Asthma guidelines) were evaluated using logistic and multinomial regressions, adjusted for age, sex and smoking status, with study areas included as a random effect. Statistically significant positive associations were observed between uncontrolled adult-onset asthma and both past 12-month and 10-year exposure to any occupational asthmagens (OR (95% CI) 1.6 (1.0-2.40) and 1.7 (1.2-2.5), respectively); high (1.7 (1.0-2.8) and 1.9 (1.3-2.9), respectively) and low (1.6 (1.0-2.7) and 1.8 (1.2-2.7), respectively) molecular weight agents; and cleaning agents (2.0 (1.1-3.6) and 2.3 (1.4-3.6), respectively), with stronger associations for long-term exposures. These associations were mainly explained by the exacerbation domain of asthma control and no associations were observed between asthmagens and partly controlled asthma. These findings suggest that occupational exposure to asthmagens is associated with uncontrolled adult-onset asthma. Occupational risk factors should be quickly identified to prevent uncontrolled asthma.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Carsin, Anne-Elie (author)
  • Siroux, Valerie (author)
  • Radon, Katja (author)
  • Norbäck, DanUppsala universitet,Arbets- och miljömedicin(Swepub:uu)dagnorba (author)
  • Torén, Kjell,1952Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine(Swepub:gu)xtorkj (author)
  • Olivieri, Mario (author)
  • Urrutia, Isabel (author)
  • Cazzoletti, Lucia (author)
  • Jacquemin, Benedicte (author)
  • Benke, Geza (author)
  • Kromhout, Hans (author)
  • Mirabelli, Maria C. (author)
  • Mehta, Amar J. (author)
  • Schluenssen, Vivi (author)
  • Sigsgaard, Torben (author)
  • Blanc, Paul D. (author)
  • Kogevinas, Manolis (author)
  • Anto, Josep M. (author)
  • Zock, Jan-Paul (author)
  • Uppsala universitetArbets- och miljömedicin (creator_code:org_t)

Related titles

  • In:European Respiratory Journal: European Respiratory Society (ERS)43:2, s. 374-3860903-19361399-3003

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