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- Helenius, MalinUppsala universitet,Enheten för radiologi (author)
Comparison of post contrast CT urography phases in bladder cancer detection
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- 2015-05-24
- Springer Science and Business Media LLC,2016
- printrdacarrier
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- LIBRIS-ID:oai:DiVA.org:uu-221282
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-221282URI
- https://doi.org/10.1007/s00330-015-3844-7DOI
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- Language:English
- Summary in:English
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- Objectives The aim of this study was to investigate which post-contrast phase(s) in a four-phase CT urography protocol is (are) most suitable for bladder cancer detection. Methods The medical records of 106 patients with visible haematuria who underwent a CT urography examination, including unenhanced, enhancement-triggered corticomedullary (CMP), nephrographic (NP) and excretory (EP) phases, were reviewed. The post-contrast phases (n = 318 different phases) were randomized into an evaluation order and blindly reviewed by two uroradiologists. Results Twenty-one patients were diagnosed with bladder cancer. Sensitivity for bladder cancer detection was 0.95 in CMP, 0.83 in NP and 0.81 in EP. Negative predictive value (NPV) was 0.99 in CMP, 0.96 in NP and 0.95 in EP. The sensitivity was higher in CMP than in both NP (p-value 0.016) and EP (p-value 0.0003). NPV was higher in CMP than in NP (p-value 0.024) and EP (p-value 0.002). Conclusion In the CT urography protocol with enhancement-triggered scan, sensitivity and NPV were highest in the corticomedullary phase, and this phase should be used for bladder assessment.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
- Multidetector computed tomography; Urography; Urinary bladder neoplasms; Haematuria; Early detection of cancer
- Radiologi
- Radiology
Added entries (persons, corporate bodies, meetings, titles ...)
- Dahlman, PärUppsala universitet,Enheten för radiologi(Swepub:uu)padah257 (author)
- Lönnemark, MariaUppsala universitet,Enheten för radiologi(Swepub:uu)malon030 (author)
- Brekkan, EinarUppsala universitet,Urologkirurgi(Swepub:uu)eibre839 (author)
- Wernroth, LisaUppsala universitet,Uppsala kliniska forskningscentrum (UCR)(Swepub:uu)lisawern (author)
- Magnusson, AndersUppsala universitet,Enheten för radiologi(Swepub:uu)anmag679 (author)
- Uppsala universitetEnheten för radiologi (creator_code:org_t)
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- In:European Radiology: Springer Science and Business Media LLC26:2, s. 585-5910938-79941432-1084
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