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Staged pathology in...
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Alafuzoff, IrinaUppsala universitet,Molekylär och morfologisk patologi
(author)
Staged pathology in Parkinson's disease
- Article/chapterEnglish2014
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Numbers
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LIBRIS-ID:oai:DiVA.org:uu-224022
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-224022URI
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https://doi.org/10.1016/S1353-8020(13)70016-6DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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There has been a tremendous development since a regional progression of pathology in subjects with Lewy bodies (LB) was initially proposed 30 years ago. The entity of dementia with Lewy bodies has been acknowledged, the main protein constituent of LBs--aggregated α-synuclein (αS)--has been identified and a stepwise progression of the pathology has been reported. Implementation of the staging strategies published provides a common ground for handling a case with a suspected α-synucleinopathy. It is always important to state the staging strategy implemented while assessing a case, as the strategy applied might influence both the reported stage of LB pathology and, ultimately, the final diagnosis of the patient.
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Parkkinen, Laura
(author)
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Uppsala universitetMolekylär och morfologisk patologi
(creator_code:org_t)
Related titles
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In:Parkinsonism & Related Disorders20:Suppl. 1, s. S57-S611353-80201873-5126
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