Does treatment with an insulin pump improve glycaemic control in children and adolescents with type 1 diabetes?: A retrospective case-control study

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Örtqvist Eva) > Does treatment with...

1 of 19
Previous record
Next record
To hitlist

Details
MARC

Brorsson, Anna Lena,1964-Karolinska Institutet,Karolinska institutet (author)

Does treatment with an insulin pump improve glycaemic control in children and adolescents with type 1 diabetes? : A retrospective case-control study

Article/chapterEnglish2015

Publisher, publication year, extent ...

2014-10-20
Hindawi Limited,2015
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:uu-239774
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-239774URI
https://doi.org/10.1111/pedi.12209DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:132162951URI
https://urn.kb.se/resolve?urn=urn:nbn:se:du-27247URI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

OBJECTIVE: To investigate long-term effects on glycaemic control, ketoacidosis, serious hypoglycaemic events, insulin requirements, and body mass index standard deviation scores (BMI-SDS) in children and adolescents with type 1 diabetes starting on continuous subcutaneous insulin infusion (CSII) compared with children and adolescents treated with multiple daily injections (MDI).METHODS: This retrospective case-control study compares 216 patients starting CSII with a control group on MDI (n = 215), matched for glycated hemoglobin (HbA1c), sex, and age during a 2-yr period. Variables collected were gender, age, HbA1c, insulin requirement, BMI, BMI-SDS, ketoacidosis, and serious hypoglycaemic events.RESULTS: In the CSII group there was an improvement in HbA1c after 6 and 12 months compared with the MDI group. For boys and girls separately the same effect was detected after 6 months, but only for boys after 12 months. The incidence of ketoacidosis was higher in the CSII group compared with the MDI group (2.8 vs. 0.5/100 person-yr). The incidences of severe hypoglycaemic episodes per 100 person-yr were three in the CSII group and six in the MDI group (p < 0.05). After 6, 12, and 24 months, the insulin requirement was higher in the MDI group.CONCLUSIONS: This study shows that treatment with CSII resulted in an improvement in HbA1c levels up to 1 yr and decreased the number of severe hypoglycaemic events, but the frequency of ketoacidosis increased. The major challenge is to identify methods to maintain the HbA1c improvement, especially among older children and teenagers, and reduce the frequency of ketoacidosis.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Endokrinologi och diabetes hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Endocrinology and Diabetes hsv//eng
adolescent
case-control studies
child
diabetes mellitus type 1
insulin infusion systems

Added entries (persons, corporate bodies, meetings, titles ...)

Viklund, GunnelKarolinska Institutet (author)
Örtqvist, EvaKarolinska Institutet (author)
Lindholm Olinder, Anna,1960-Karolinska Institutet,Uppsala universitet,Klinisk diabetologi och metabolism,Karolinska Inst, Dept Clin Sci & Educ, Stockholm, Sweden(Swepub:uu)annli614 (author)
Karolinska InstitutetKarolinska institutet (creator_code:org_t)

Related titles

In:Pediatric Diabetes: Hindawi Limited16:7, s. 546-5531399-543X1399-5448

Internet link

Find in a library

Pediatric Diabetes (Search for host publication in LIBRIS)

To the university's database

1 of 19
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Brorsson, Anna L ...; Viklund, Gunnel; Örtqvist, Eva; Lindholm Olinder ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Endocrinology an ...

Articles in the publication: Pediatric Diabet ...

By the university: Uppsala University; Karolinska Institutet; Högskolan Dalarna

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se