Sökning: L773:1423 0399 OR L773:0042 1138 >
Molecular Markers f...
Molecular Markers for Bladder Cancer Screening, Early Diagnosis, and Surveillance : The WHO/ICUD Consensus
-
Schmitz-Draeger, Bernd J. (författare)
-
Droller, Michael (författare)
-
Lokeshwar, Vinata B. (författare)
-
visa fler...
-
Lotan, Yair (författare)
-
Hudson, M'Liss A. (författare)
-
van Rhijn, Bas W. (författare)
-
Marberger, Michael J. (författare)
-
Fradet, Yves (författare)
-
Hemstreet, George P. (författare)
-
- Malmström, Per-Uno (författare)
- Uppsala universitet,Urologkirurgi
-
Ogawa, Osamu (författare)
-
Karakiewicz, Pierre I. (författare)
-
Shariat, Shahrokh F. (författare)
-
visa färre...
-
(creator_code:org_t)
- 2014-12-10
- 2015
- Engelska.
-
Ingår i: Urologia internationalis. - : S. Karger AG. - 0042-1138 .- 1423-0399. ; 94:1, s. 1-24
- Relaterad länk:
-
https://www.karger.c...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Due to the lack of disease-specific symptoms, diagnosis and follow-up of bladder cancer has remained a challenge to the urologic community. Cystoscopy, commonly accepted as a gold standard for the detection of bladder cancer, is invasive and relatively expensive, while urine cytology is of limited value specifically in low-grade disease. Over the last decades, numerous molecular assays for the diagnosis of urothelial cancer have been developed and investigated with regard to their clinical use. However, although all of these assays have been shown to have superior sensitivity as compared to urine cytology, none of them has been included in clinical guidelines. The key reason for this situation is that none of the assays has been included into clinical decision-making so far. We reviewed the current status and performance of modern molecular urine tests following systematic analysis of the value and limitations of commercially available assays. Despite considerable advances in recent years, the authors feel that at this stage the added value of molecular markers for the diagnosis of urothelial tumors has not yet been identified. Current data suggest that some of these markers may have the potential to play a role.in screening and surveillance of bladder cancer. Well-designed protocols and prospective, controlled trials will be needed to provide the basis to determine whether integration of molecular markers into clinical decision-making will be of value in the future.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- Diagnosis
- Surveillance
- Bladder cancer
- Molecular markers
- Urine
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Schmitz-Draeger, ...
-
Droller, Michael
-
Lokeshwar, Vinat ...
-
Lotan, Yair
-
Hudson, M'Liss A ...
-
van Rhijn, Bas W ...
-
visa fler...
-
Marberger, Micha ...
-
Fradet, Yves
-
Hemstreet, Georg ...
-
Malmström, Per-U ...
-
Ogawa, Osamu
-
Karakiewicz, Pie ...
-
Shariat, Shahrok ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Urologi och njur ...
- Artiklar i publikationen
-
Urologia interna ...
- Av lärosätet
-
Uppsala universitet