WFRF:(Dickman Paul W.)
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- Andersson, Therese M-LKarolinska Institutet (author)
The loss in expectation of life after colon cancer : a population-based study
- Article/chapterEnglish2015
Publisher, publication year, extent ...
- 2015-05-17
- Springer Science and Business Media LLC,2015
- electronicrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-256233
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-256233URI
- https://doi.org/10.1186/s12885-015-1427-2DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:131283194URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Background: To demonstrate how assessment of life expectancy and loss in expectation of life can be used to address a wide range of research questions of public health interest pertaining to the prognosis of cancer patients. Methods: We identified 135,092 cases of colon adenocarcinoma diagnosed during 1961-2011 from the population-based Swedish Cancer Register. Flexible parametric survival models for relative survival were used to estimate the life expectancy and the loss in expectation of life. Results: The loss in expectation of life for males aged 55 at diagnosis was 13.5 years (95 % CI 13.2-13.8) in 1965 and 12.8 (12.4-13.3) in 2005. For males aged 85 the corresponding figures were 3.21 (3.15-3.28) and 2.10 (2.04-2.17). The pattern was similar for females, but slightly greater loss in expectation of life. The loss in expectation of life is reduced given survival up to a certain time point post diagnosis. Among patients diagnosed in 2011, 945 life years could potentially be saved if the colon cancer survival among males could be brought to the same level as for females. Conclusion: Assessment of loss in expectation of life facilitates the understanding of the impact of cancer, both on individual and population level. Clear improvements in survival among colon cancer patients have led to a gain in life expectancy, partly due to a general increase in survival from all causes.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
- Colon cancer
- Survival
- Life expectancy
- Population-based
- Flexible parametric model
- Life years lost
- Sweden
Added entries (persons, corporate bodies, meetings, titles ...)
- Dickman, Paul W.Karolinska Institutet (author)
- Eloranta, SandraKarolinska Institutet (author)
- Sjovall, AnnikaKarolinska Institutet (author)
- Lambe, MatsUppsala universitet,Uppsala kliniska forskningscentrum (UCR) (author)
- Lambert, Paul C.Karolinska Institutet (author)
- Karolinska InstitutetUppsala kliniska forskningscentrum (UCR) (creator_code:org_t)
Related titles
- In:BMC Cancer: Springer Science and Business Media LLC151471-2407
Internet link
- https://doi.org/10.1186/s12885-015-1427-2Fulltext
- https://uu.diva-portal.org/smash/get/diva2:826128/FULLTEXT01.pdffulltext:print
- https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-015-1427-2
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-256233
- https://doi.org/10.1186/s12885-015-1427-2
- http://kipublications.ki.se/Default.aspx?queryparsed=id:131283194
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- Lambert, Paul C.
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- MEDICAL AND HEALTH SCIENCES
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