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Graft function 1 ye...
Graft function 1 year after pregnancy in an islet-transplanted patient
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- Schive, Simen W. (författare)
- Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, N-0424 Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.
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- Scholz, Hanne (författare)
- Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, N-0424 Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.
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- Sahraoui, Afaf (författare)
- Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, N-0424 Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.
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- Kloster-Jensen, Kristine (författare)
- Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, N-0424 Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.
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- Hafsahl, Geir (författare)
- Oslo Univ Hosp, Dept Radiol, Oslo, Norway.
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- Korsgren, Olle (författare)
- Uppsala universitet,Klinisk immunologi
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- Foss, Aksel (författare)
- Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway.;Oslo Univ Hosp, Inst Surg Res, N-0424 Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway.
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- Jenssen, Trond G. (författare)
- Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway.;UiT Arctic Univ Norway, Metab & Renal Res Grp, Tromso, Norway.
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Oslo Univ Hosp, Dept Transplant Med, N-0424 Oslo, Norway;Oslo Univ Hosp, Inst Surg Res, N-0424 Oslo, Norway.;Univ Oslo, Inst Clin Med, Oslo, Norway. Oslo Univ Hosp, Dept Radiol, Oslo, Norway. (creator_code:org_t)
- 2015-05-11
- 2015
- Engelska.
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Ingår i: Transplant International. - : Frontiers Media SA. - 0934-0874 .- 1432-2277. ; 28:10, s. 1235-1239
- Relaterad länk:
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Pancreatic islet transplantation is a treatment option for patients with type 1 diabetes (T1D), but pregnancy has generally not been advised for women after receiving an islet allograft. We hereby describe what is to our knowledge the first successful pregnancy and persistent graft function in a woman 4years after her initial islet transplantation. A 37-year-old woman with brittle type 1 diabetes was transplanted with two separate islet graft infusions, eventually becoming insulin independent. Ten months after her second transplantation, her immunosuppression was switched from tacrolimus and sirolimus to tacrolimus, azathioprine, and prednisolone, due to her wish to become pregnant. She became pregnant one year later, and after 38weeks of uncomplicated pregnancy, she gave birth to a healthy child by C-section. The current report suggests that pregnancy and childbirth can be accomplished after islet transplantation without loss of islet graft function.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Nyckelord
- glucocorticoids
- islet transplantation
- pregnancy
- type 1 diabetes
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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