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Analysis of the Eff...
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Shaw, Bronwen E.Med Coll Wisconsin, Dept Med, CIBMTR, Milwaukee, WI 53226 USA.
(författare)
Analysis of the Effect of Race, Socioeconomic Status, and Center Size on Unrelated National Marrow Donor Program Donor Outcomes : Donor Toxicities Are More Common at Low-Volume Bone Marrow Collection Centers
- Artikel/kapitelEngelska2015
Förlag, utgivningsår, omfång ...
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Elsevier BV,2015
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-264817
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-264817URI
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https://doi.org/10.1016/j.bbmt.2015.06.013DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:132039724URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Previous studies have shown that risks of collection-related pain and symptoms are associated with sex, body mass index, and age in unrelated donors undergoing collection at National Marrow Donor Program centers. We hypothesized that other important factors (race, socioeconomic status [SES], and number of procedures at the collection center) might affect symptoms in donors. We assessed outcomes in 2726 bone marrow (BM) and 6768 peripheral blood stem cell (PBSC) donors collected between 2004 and 2009. Pain/symptoms are reported as maximum levels over mobilization and collection (PBSC) or within 2 days of collection (BM) and at 1 week after collection. For PBSC donors, race and center volumes were not associated with differences in pain/symptoms at any time. PBSC donors with high SES levels reported higher maximum symptom levels 1 week after donation (P = .017). For BM donors, black males reported significantly higher levels of pain (OR, 1.90; CI, 1.14 to 3.19; P = .015). No differences were noted by SES group. BM donors from low-volume centers reported more toxicity (OR, 2.09; CI, 1.26 to 3.46; P = .006). In conclusion, race and SES have a minimal effect on donation-associated symptoms. However, donors from centers performing <= 1 BM collection every 2 months have more symptoms after BM donation. Approaches should be developed by registries and low-volume centers to address this issue.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Logan, Brent R.Med Coll Wisconsin, Dept Med, CIBMTR, Milwaukee, WI 53226 USA.;CIBMTR, Natl Marrow Donor Program Be Match, Minneapolis, MN USA.
(författare)
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Kiefer, Deidre M.CIBMTR, Natl Marrow Donor Program Be Match, Minneapolis, MN USA.
(författare)
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Chitphakdithai, PintipCIBMTR, Natl Marrow Donor Program Be Match, Minneapolis, MN USA.
(författare)
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Pedersen, Tanya L.Allina Hlth, Minneapolis, MN USA.
(författare)
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Abdel-Azim, HishamUniv So Calif, Keck Sch Med, Childrens Hosp Los Angeles, Div Hematol Oncol & Blood & Marrow Transplantat, Los Angeles, CA 90033 USA.
(författare)
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Abidi, Muneer H.Wayne State Univ, Karmanos Canc Inst, Dept Oncol, Div BMT, Detroit, MI USA.
(författare)
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Akpek, GorgunBanner MD Anderson Canc Ctr, Stem Cell Transplantat & Cellular Therapy Program, Gilbert, AZ USA.
(författare)
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Diaz, Miguel A.Hosp Infantil Univ Nino Jesus, Dept Hematol Oncol, Madrid, Spain.
(författare)
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Artz, Andrew S.
(författare)
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Dandoy, ChristopherUniv Chicago, Hematol Oncol Sect, Chicago, IL 60637 USA.;Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA.
(författare)
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Gajewski, James L.Oregon Hlth & Sci Univ, Portland, OR 97201 USA.
(författare)
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Hematti, PeimanUniv Wisconsin Hosp & Clin, Div Hematol Oncol Bone Marrow Transplantat, Madison, WI 53792 USA.
(författare)
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Kamble, Rammurti T.Baylor Coll Med, Ctr Cell & Gene Therapy, Div Hematol & Oncol, Houston, TX 77030 USA.
(författare)
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Kasow, Kimberley A.Univ N Carolina, Dept Pediat, Div Hematol Oncol, Chapel Hill, NC USA.
(författare)
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Lazarus, Hillard M.Univ Hosp Case Med Ctr, Seidman Canc Ctr, Cleveland, OH USA.
(författare)
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Liesveld, Jane L.Univ Rochester, Med Ctr, Dept Med, Rochester, NY 14642 USA.
(författare)
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Majhail, Navneet S.Cleveland Clin, Taussig Canc Inst, Blood & Marrow Transplant Program, Cleveland, OH 44106 USA.
(författare)
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O'Donne, Paul V.Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA.
(författare)
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Olsson, Richard F.Karolinska Institutet,Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Karolinska Inst, Dept Lab Med, Div Therapeut Immunol, Stockholm, Sweden.(Swepub:uu)riols677
(författare)
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Savani, Bipin N.Vanderbilt Univ, Med Ctr, Dept Med, Div Hematol Oncol, Nashville, TN USA.
(författare)
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Schears, Raquel M.Mayo Clin, Rochester, MN USA.
(författare)
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Stroncek, David F.NIH, Dept Transfus Med, Clin Ctr, Bethesda, MD 20892 USA.
(författare)
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Switzer, Galen E.Univ Pittsburgh, Pittsburgh, PA USA.
(författare)
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Williams, Eric P.BeTheMatch Natl Marrow Donor Program, Minneapolis, MN USA.
(författare)
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Wingard, John R.Univ Florida, Dept Med, Div Hematol & Oncol, Gainesville, FL USA.
(författare)
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Wirk, Baldeep M.Seattle Canc Care Alliance, Div Bone Marrow Transplant, Seattle, WA USA.
(författare)
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Confer, Dennis L.BeTheMatch Natl Marrow Donor Program, Minneapolis, MN USA.
(författare)
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Pulsipher, Michael A.Univ So Calif, Keck Sch Med, Childrens Hosp Los Angeles, Div Hematol Oncol & Blood & Marrow Transplantat, Los Angeles, CA 90033 USA.
(författare)
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Med Coll Wisconsin, Dept Med, CIBMTR, Milwaukee, WI 53226 USA.Med Coll Wisconsin, Dept Med, CIBMTR, Milwaukee, WI 53226 USA.;CIBMTR, Natl Marrow Donor Program Be Match, Minneapolis, MN USA.
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Biology of blood and marrow transplantation: Elsevier BV21:10, s. 1830-18381083-87911523-6536
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Till lärosätets databas
- Av författaren/redakt...
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Shaw, Bronwen E.
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Logan, Brent R.
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Kiefer, Deidre M ...
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Chitphakdithai, ...
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Pedersen, Tanya ...
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Abdel-Azim, Hish ...
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visa fler...
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Abidi, Muneer H.
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Akpek, Gorgun
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Diaz, Miguel A.
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Artz, Andrew S.
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Dandoy, Christop ...
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Gajewski, James ...
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Hematti, Peiman
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Kamble, Rammurti ...
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Kasow, Kimberley ...
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Lazarus, Hillard ...
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Liesveld, Jane L ...
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Majhail, Navneet ...
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O'Donne, Paul V.
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Olsson, Richard ...
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Savani, Bipin N.
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Schears, Raquel ...
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Stroncek, David ...
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Switzer, Galen E ...
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Williams, Eric P ...
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Wingard, John R.
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Wirk, Baldeep M.
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Confer, Dennis L ...
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Pulsipher, Micha ...
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Biology of blood ...
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Uppsala universitet
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