id:"swepub:oai:DiVA.org:uu-272617"
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- Nilsson, B O (author)
Monoclonal antibodies against human blastocysts.
- Article/chapterEnglish1995
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- 1995
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- LIBRIS-ID:oai:DiVA.org:uu-272617
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-272617URI
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- Language:English
- Summary in:English
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- A panel of monoclonal antibodies against the implanting mouse blastocyst was tested for cross-reactivity to human blastocysts. The monoclonal antibodies were produced by intrasplenic immunization with living mouse blastocysts or egg-cylinders. Among the 13 anti-mouse blastocyst antibodies checked, 6 ones detected antigen epitopes also in human blastocysts. If the mouse-human cross-reacting antibodies detect similar antigens in blastocysts of the two species, the results imply that anti-mouse blastocyst antibodies with specific properties could be used for studying human blastocysts. This procedure opens for a way to obtain monoclonal antibodies for analysing human blastocysts.
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- Hjortberg, M (author)
- Olovsson, Matts,1958-Uppsala universitet,Institutionen för kvinnors och barns hälsa,Reproduktionsbiologi(Swepub:uu)mattolov (author)
- Sjögren, A (author)
- Hamberger, L (author)
- Uppsala universitetInstitutionen för kvinnors och barns hälsa (creator_code:org_t)
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- In:Upsala Journal of Medical Sciences100:30300-97342000-1967
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