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Promising clinical outcome of elderly with TBI after modern neurointensive care

Merzo, Abraham (författare)
Uppsala universitet,Neurokirurgi
Lenell, Samuel (författare)
Uppsala universitet,Neurokirurgi
Nyholm, Lena (författare)
Uppsala universitet,Neurokirurgi
visa fler...
Enblad, Per (författare)
Uppsala universitet,Neurokirurgi
Lewen, Anders (författare)
Uppsala universitet,Neurokirurgi
visa färre...
 (creator_code:org_t)
2015-11-18
2016
Engelska.
Ingår i: Acta Neurochirurgica. - : Springer Science and Business Media LLC. - 0001-6268 .- 0942-0940. ; 158:1, s. 125-133
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • The increasing number of elderly patients with traumatic brain injury (TBI) leads to specific neurointensive care (NIC) challenges. Therefore, elderly subjects with TBI need to be further studied. In this study we evaluated the demographics, management and outcome of elderly TBI patients receiving modern NIC. Patients referred to our NIC unit between 2008 and 2010 were included. Patients were divided in two age groups, elderly (E) a parts per thousand yen65 years and younger (Y) 64-15 years. Parameters studied were the dominant finding on CT scans, neurological motor skills and consciousness, type of monitoring, neurosurgical procedures/treatments and Glasgow Outcome Scale Extended score at 6 months after injury. Sixty-two E (22 %) and 222 Y (78 %) patients were included. Falls were more common in E (81 %) and vehicle accidents were more common in Y patients (37 %). Acute subdural hematoma was significantly more common in E (50 % of cases) compared to Y patients (18 %). Intracranial pressure was monitored in 44 % of E and 57 % of Y patients. Evacuation of significant mass lesions was performed more common in the E group. The NIC mortality was similar in both groups (4-6 %). Favorable outcome was observed in 72 % of Y and 51 % of E patients. At the time of follow-up 25 % of E and 7 % of Y patients had died. The outcome of elderly patients with TBI was significantly worse than in younger patients, as expected. However, as much as 51 % of the elderly patients showed a favorable outcome after NIC. We believe that these results encourage modern NIC in elderly patients with TBI. We need to study how secondary brain injury mechanisms differ in the older patients and to identify specific outcome predictors for elderly patients with TBI.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

Nyckelord

Traumatic brain injury
Outcome
Elderly
Neurointensive care
Secondary injury

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Merzo, Abraham
Lenell, Samuel
Nyholm, Lena
Enblad, Per
Lewen, Anders
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MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Klinisk medicin
och Neurologi
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Acta Neurochirur ...
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Uppsala universitet

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