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- Lundborg, Cecilia StalsbyKarolinska Institutet,Karolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden. (författare)
Protocol : a 'One health' two year follow-up, mixed methods study on antibiotic resistance, focusing children under 5 and their environment in rural India
- Artikel/kapitelEngelska2015
Förlag, utgivningsår, omfång ...
- 2015-12-30
- Springer Science and Business Media LLC,2015
- electronicrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:uu-274928
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-274928URI
- https://doi.org/10.1186/s12889-015-2632-2DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:132688946URI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- Background: Antibiotic resistance has been referred to as 'the greatest malice of the 21st century' and a global action plan was adopted by the World Health Assembly in 2015. There is a wealth of independent studies regarding antibiotics and resistant bacteria in humans, animals and their environment, however, integrated studies are lacking, particularly ones that simultaneously also take into consideration the health related behaviour of participants and healthcare providers. Such, 'One health' studies are difficult to implement, because of the complex teamwork that they entail. This paper describes the protocol of a study that investigates 'One health' issues regarding antibiotic use and antibiotic resistance in children and their environment in Indian villages. Methods/Design: Both quantitative and qualitative studies are planned for a cohort of children, from 6 villages, and their surrounding environment. Repeated or continues data collection is planned over 2 years for quantitative studies. Qualitative studies will be conducted once. Studies include parents' health seeking behavior for their children (1-3 years of age at the onset), prescribing pattern of formal and informal healthcare providers, analysis of phenotypic antibiotic resistance of Escherichia coli from samples of stool from children and village animals, household drinking water, village source water and waste water, and investigation on molecular mechanisms governing resistance. Analysis of interrelationship of these with each other will also be done as basis for future interventions. Ethics approval has been obtained from the Institutional Ethics Committee R.D. Gardi Medical College, Ujjain, India (No: 2013/07/17-311). Discussion: The findings of the study presented in this protocol will add to our knowledge about the multi-factorial nature of causes governing antibiotic use and antibiotic resistance from a 'One health' perspective. Our study will be the first of its kind addressing antibiotic use and resistance issues related to children in a One-health approach, particularly for rural India.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
- One health
- Health seeking behaviour
- Antibiotic prescribing
- Formal and informal health care providers
- Escherichia coli in stools of children and water
- Antibiotic resistance
- Molecular basis of resistance
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Diwan, VishalKarolinska Institutet,Karolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden.;RD Gardi Med Coll, Dept Publ Hlth & Environm, Ujjain, Madhya Pradesh, India.;RD Gardi Med Coll, Int Ctr Hlth Res, Ujjain, Madhya Pradesh, India. (författare)
- Pathak, AshishKarolinska Institutet,Uppsala universitet,Internationell mödra- och barnhälsovård (IMCH),Karolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden.;RD Gardi Med Coll, Dept Pediat, Ujjain, Madhya Pradesh, India.(Swepub:uu)ashpa703 (författare)
- Purohit, Manju R.Karolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden.;RD Gardi Med Coll, Dept Pathol, Ujjain, Madhya Pradesh, India.;Ujjain Charitable Trust Hosp & Res Ctr, Cent Clin Lab, Ujjain, Madhya Pradesh, India. (författare)
- Shah, HarshadaRD Gardi Med Coll, Dept Microbiol, Ujjain, Madhya Pradesh, India. (författare)
- Sharma, MeghaKarolinska Institutet,Karolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden.;RD Gardi Med Coll, Dept Pharmacol, Ujjain, Madhya Pradesh, India. (författare)
- Mahadik, Vijay K.Ujjain Charitable Trust Hosp & Res Ctr, Ujjain, Madhya Pradesh, India. (författare)
- Tamhankar, Ashok J.Karolinska Institutet,Karolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden.;RD Gardi Med Coll, Dept Environm Med, Indian Initiat Management Antibiot Resistance, Ujjain, Madhya Pradesh, India. (författare)
- Karolinska InstitutetKarolinska Inst, Dept Publ Hlth Sci Global Hlth Hlth Syst & Policy, Focusing Antibiot, S-17177 Stockholm, Sweden. (creator_code:org_t)
Sammanhörande titlar
- Ingår i:BMC Public Health: Springer Science and Business Media LLC151471-2458
Internetlänk
- https://doi.org/10.1186/s12889-015-2632-2Fulltext
- https://uu.diva-portal.org/smash/get/diva2:898121/FULLTEXT01.pdffulltext:print
- https://bmcpublichealth.biomedcentral.com/track/pdf/10.1186/s12889-015-2632-2
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-274928
- https://doi.org/10.1186/s12889-015-2632-2
- http://kipublications.ki.se/Default.aspx?queryparsed=id:132688946
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