Search: WFRF:(Kjellén Lars)
> (2000-2021) >
Differences in heal...
Differences in health related quality of life in the randomised ARTSCAN study; accelerated vs. conventional radiotherapy for head and neck cancer. A five year follow up
-
- Nyqvist, Johanna (author)
- Umeå universitet,Öron- näs- och halssjukdomar,Department of Otolaryngology and Head and Neck Surgery, Skåne University Hospital, Lund
-
- Fransson, Per (author)
- Umeå University,Umeå universitet,Institutionen för omvårdnad
-
- Laurell, Göran (author)
- Umeå University,Umeå universitet,Uppsala universitet,Öron-, näs- och halssjukdomar,Umea Univ, Dept Clin Sci Otolaryngol & Head & Neck Surg, S-90187 Umea, Sweden.,Öron- näs- och halssjukdomar,Department of Otolaryngology and Head and Neck Surgery, Uppsala University Hospital
-
show more...
-
- Hammerlid, Eva (author)
- Sahlgrens Univ Hosp, Dept Otolaryngol & Head & Neck Surg, Gothenburg, Sweden.,Sahlgrenska University Hospital
-
- Kjellén, Elisabeth (author)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
-
- Franzén, Lars (author)
- Umeå University,Umeå universitet,Onkologi
-
- Söderström, Karin (author)
- Umeå University,Umeå universitet,Onkologi
-
- Wickart-Johansson, Gun (author)
- Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden.,Karolinska University Hospital
-
- Friesland, Signe (author)
- Karolinska Institutet
-
- Sjodin, Helena (author)
- Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden.,Karolinska University Hospital
-
- Brun, Eva (author)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
-
- Ask, Anders (author)
- Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
-
- Nilsson, Per (author)
- Lund University,Lunds universitet,Medicinsk strålningsfysik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical Radiation Physics, Lund,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
-
- Ekberg, Lars (author)
- Lund Univ, Skane Univ Hosp, Dept Oncol & Radiat Phys, S-22100 Lund, Sweden.,Skåne University Hospital
-
- Bjork-Eriksson, Thomas (author)
- Sahlgrens Univ Hosp, Dept Oncol, Gothenburg, Sweden.
-
- Nyman, Jan (author)
- Sahlgrens Univ Hosp, Dept Oncol, Gothenburg, Sweden.
-
- Loden, Britta (author)
- Karlstad Cent Hosp, Dept Clin Oncol, Karlskrona, Sweden.
-
- Lewin, Freddi (author)
- Ryhov Cty Hosp, Dept Oncol, Jonkoping, Sweden.
-
- Reizenstein, Johan (author)
- Orebro Univ Hosp, Dept Oncol, Orebro, Sweden.
-
- Lundin, Erik (author)
- Ryhov Cty Hosp, Dept Oncol, Jonkoping, Sweden.
-
- Zackrisson, Björn (author)
- Umeå universitet,Onkologi
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2016
- 2016
- English.
-
In: Radiotherapy and Oncology. - : Elsevier BV. - 0167-8140 .- 1879-0887. ; 118:2, s. 335-341
- Related links:
-
http://www.ncbi.nlm....
-
show more...
-
http://dx.doi.org/10...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
https://lup.lub.lu.s...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Background and purpose: Health related quality of life (HRQoL) was assessed in the randomised, prospective ARTSCAN study comparing conventional radiotherapy (CF) with accelerated radiotherapy (AF) for head and neck cancer. Material and methods: 750 patients with squamous cell carcinoma (of any grade and stage) in the oral cavity, oro-, or hypopharynx or larynx (except T1-2, NO glottic carcinoma) without distant metastases were randomised to either conventional fractionation (2 Gy/day, 5 days/week in 49 days, total dose 68 Gy) or accelerated fractionation (1.1 + 2.0 Gy/day, 5 days/week in 35 days, total dose 68 Gy). HRQoL was assessed with EORTC QLQ-C30, QLQ-H&N35 and HADS at baseline, at end of radiotherapy (eRT) and at 3 and 6 months and 1, 2 and 5 years after start of treatment. Results: The AF group reported HRQoL was significantly lower at eRT and at 3 months for most symptoms, scales and functions. Few significant differences were noted between the groups at 6 months and 5 years. Scores related to functional oral intake never reached baseline. Conclusion: In comparison to CF, AF has a stronger adverse effect on HRQoL in the acute phase.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Keyword
- Health related quality of life
- Accelerated radiotherapy
- Head and neck cancer
- Quality of life
- Accelerated fractionation
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Nyqvist, Johanna
-
Fransson, Per
-
Laurell, Göran
-
Hammerlid, Eva
-
Kjellén, Elisabe ...
-
Franzén, Lars
-
show more...
-
Söderström, Kari ...
-
Wickart-Johansso ...
-
Friesland, Signe
-
Sjodin, Helena
-
Brun, Eva
-
Ask, Anders
-
Nilsson, Per
-
Ekberg, Lars
-
Bjork-Eriksson, ...
-
Nyman, Jan
-
Loden, Britta
-
Lewin, Freddi
-
Reizenstein, Joh ...
-
Lundin, Erik
-
Zackrisson, Björ ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Radiology Nuclea ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Nursing
- Articles in the publication
-
Radiotherapy and ...
- By the university
-
Uppsala University
-
Umeå University
-
Lund University
-
Karolinska Institutet