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Postoperative morta...
Postoperative mortality 90 days after robot-assisted laparoscopic prostatectomy and retropubic radical prostatectomy : a nationwide population-based study
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- Björklund, Johan (author)
- Karolinska Institutet
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- Folkvaljon, Yasin (author)
- Uppsala Univ Hosp, Reg Canc Ctr, Uppsala, Sweden.
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- Cole, Alexander (author)
- Harvard Med Sch, Brigham & Womens Hosp, Div Urol Surg, Boston, MA USA.
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- Carlsson, Stefan (author)
- Karolinska Institutet
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- Robinson, David (author)
- Umeå universitet,Urologi och andrologi,Department of Urology, Ryhov County Hospital, Jönköping, Sweden,Ryhov Cty Hosp, Dept Urol, Jonkoping, Sweden.;Umea Univ Hosp, Dept Surg & Perioperat Sci Urol & Androl, Umea, Sweden.
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- Loeb, Stacy (author)
- NYU, Dept Urol Populat Hlth, Laura & Isaac Perlmutter Canc Ctr, New York, NY USA.
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- Stattin, Pär (author)
- Umeå universitet,Uppsala universitet,Urologkirurgi,Urologi och andrologi,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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- Akre, Olof (author)
- Karolinska Institutet
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Karolinska Institutet Uppsala Univ Hosp, Reg Canc Ctr, Uppsala, Sweden (creator_code:org_t)
- 2016-02-15
- 2016
- English.
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In: BJU International. - : Wiley. - 1464-4096 .- 1464-410X. ; 118:2, s. 302-306
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Abstract
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- Objective To assess 90-day postoperative mortality after robot-assisted laparoscopic radical prostatectomy (RARP) and retropubic radical prostatectomy (RRP) using nationwide population-based registry data. Patients and Methods We conducted a cohort study using the National Prostate Cancer Register of Sweden, including 22 344 men with localized prostate cancer of clinical stage T1-T3, whose prostate-specific antigen levels were <50 mu g/mL and who had undergone primary radical prostatectomy in the period 1998-2012. Vital status was ascertained through the Total Population Register. The rates for 90-day postoperative mortality were analysed using logistic regression analysis, and comparisons of 90-day mortality with the background population were made using standardized mortality ratios (SMRs). Results Of the 14 820 men who underwent RRP, 29 (0.20%) died, and of the 7 524 men who underwent RARP, 10 (0.13%) died. Mortality in the cohort during the 90-day postoperative period was lower than in an age-matched background population: SMR 0.57 (95% confidence interval [CI] 0.39-0.75). There was no statistically significant difference in 90-day mortality according to surgical method: RARP vs RRP odds ratio (OR) 1.14; 95% CI 0.46-2.81. Postoperative 90-day mortality decreased over time: 2008-2012 vs 1998-2007 OR 0.44; 95% CI 0.21-0.95, mainly because of lower mortality after RARP. Conclusion The 90-day postoperative mortality rates were low after RARP and RRP and there was no statistically significant difference between the methods. Given the long life expectancy among men with low-and intermediate-risk prostate cancer, very low postoperative mortality is a prerequisite for RP, which was fulfilled by both RRP and RARP. The selection of healthy men for RP is highlighted by the lower 90-day mortality after RP compared with the background population.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Keyword
- prostate cancer
- radical prostatectomy
- retropubic prostatectomy
- robot assisted laparoscopic prostatectomy
- mortality
- 90-day postoperative
Publication and Content Type
- ref (subject category)
- art (subject category)
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