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Elective caesarean :
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Andersson, Ola,1965-Uppsala universitet,Internationell mödra- och barnhälsovård (IMCH),Department of Research and Development, Region Halland, Sweden,Perinatal, neonatal och barnkardiologisk forskning/Hellström-Westas
(författare)
Elective caesarean : does delay in cord clamping for 30 s ensure sufficient iron stores at 4 months of age? A historical cohort control study
- Artikel/kapitelEngelska2016
Förlag, utgivningsår, omfång ...
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2016-11-02
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BMJ,2016
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-308092
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-308092URI
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https://doi.org/10.1136/bmjopen-2016-012995DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-132063URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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OBJECTIVE: To compare iron stores in infants born after elective caesarean section (CS) and a 30 s delay of umbilical cord clamping with those born vaginally after early (≤10 s) or delayed (≥180 s) cord clamping.DESIGN: Prospective observational study with historical control.SETTING: Swedish county hospital.POPULATION: 64 infants born after elective CS were compared with a historical control of 166 early clamped and 168 delayed clamped after vaginal birth.METHODS: Blood and iron status were measured in blood samples collected at birth, 48-96 hours after birth, 4 and 12 months of age.PRIMARY AND SECONDARY OUTCOME MEASURES: Ferritin at 4 months of age was the primary outcome, second outcome measures were other indicators of iron status, and haemoglobin, at 4 and 12 months of age, as well as respiratory distress at 1 and 6 hours after birth.RESULTS: At 4 months infants born by elective CS had better iron status than those born vaginally subjected to early cord clamping, shown by higher adjusted mean difference of ferritin concentration (39 µg/L (95% CI 10 to 60)) and mean cell volume (1.8 fL (95% CI 0.6 to 3.0)); and lower levels of transferrin receptors (-0.39 mg/L (95% CI -0.69 to -0.08)). No differences were seen between infants born after elective CS and delayed clamped vaginally born infants at 4 months. No differences were found between groups at 12 months of age.CONCLUSIONS: Waiting to clamp the umbilical cord for 30 s after elective CS results in higher iron stores at 4 months of age compared with early cord clamping after vaginal birth, and seems to ensure iron status comparable with those achieved after 180 s delayed cord clamping after vaginal birth.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Hellström-Westas, Lena,1954-Uppsala universitet,Pediatrik,Perinatal, neonatal och barnkardiologisk forskning/Hellström-Westas(Swepub:uu)lenwe671
(författare)
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Domellöf, MagnusUmeå universitet,Pediatrik,Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden(Swepub:umu)mado0002
(författare)
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Uppsala universitetInternationell mödra- och barnhälsovård (IMCH)
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:BMJ Open: BMJ6:112044-6055
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