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Sökning: WFRF:(Björklund Bodegård Kristina) > (2015-2018) > The Cardiovascular ...

The Cardiovascular Risk of White-Coat Hypertension

Franklin, Stanley S. (författare)
Univ Calif Irvine, Sch Med, Div Cardiol, Heart Dis Prevent Program, Irvine, CA 92717 USA.
Thijs, Lutgarde (författare)
Katholieke Univ Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Studies Coordinating Ctr, Leuven, Belgium.
Asayama, Kei (författare)
Tohoku Univ, Grad Sch Pharmaceut Sci, Sendai, Miyagi, Japan.;Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan.
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Li, Yan (författare)
Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Ctr Epidemiol Studies & Clin Trials, Shanghai, Peoples R China.;Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Ctr Vasc Evaluat, Shanghai, Peoples R China.
Hansen, Tine W. (författare)
Gentofte & Res Ctr Prevent & Hlth, Steno Diabet Ctr, Gentofte, Denmark.
Boggia, Jose (författare)
Univ Republica, Hosp Clin, Ctr Nefrol, Montevideo, Uruguay.;Univ Republica, Hosp Clin, Dept Fisiopatol, Montevideo, Uruguay.
Jacobs, Lotte (författare)
Katholieke Univ Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Studies Coordinating Ctr, Leuven, Belgium.
Zhang, Zhenyu (författare)
Katholieke Univ Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Studies Coordinating Ctr, Leuven, Belgium.
Kikuya, Masahiro (författare)
Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Sendai, Miyagi, Japan.
Björklund-Bodegård, Kristina (författare)
Uppsala universitet,Geriatrik,Karolinska Inst, Danderyd Hosp, Dept Cardiol, Stockholm, Sweden.
Ohkubo, Takayoshi (författare)
Tohoku Univ, Grad Sch Pharmaceut Sci, Sendai, Miyagi, Japan.;Tohoku Univ, Grad Sch Pharmaceut Sci & Med, Sendai, Miyagi, Japan.
Yang, Wen-Yi (författare)
Katholieke Univ Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Studies Coordinating Ctr, Leuven, Belgium.
Jeppesen, Jorgen (författare)
Univ Copenhagen, Glostrup Hosp, Dept Med, Copenhagen, Denmark.
Dolan, Eamon (författare)
Addenbrooks Hosp, Cambridge Univ Hosp, Cambridge, England.
Kuznetsova, Tatiana (författare)
Inst Internal Med, Novosibirsk, Russia.
Stolarz-Skrzypek, Katarzyna (författare)
Jagiellonian Univ, Coll Med, Dept Cardiol Intervent Elect & Hypertens 1, Krakow, Poland.
Tikhonoff, Valerie (författare)
Univ Padua, Dept Med, Padua, Italy.
Malyutina, Sofia (författare)
Inst Internal Med, Novosibirsk, Russia.
Casiglia, Edoardo (författare)
Univ Padua, Dept Med, Padua, Italy.
Nikitin, Yuri (författare)
Inst Internal Med, Novosibirsk, Russia.
Lind, Lars (författare)
Uppsala universitet,Geriatrik
Sandoya, Edgardo (författare)
Asociac Espanola Primera Socorros Mutuos, Montevideo, Uruguay.
Kawecka-Jaszcz, Kalina (författare)
Jagiellonian Univ, Coll Med, Dept Cardiol Intervent Elect & Hypertens 1, Krakow, Poland.
Filipovsky, Jan (författare)
Charles Univ Prague, Fac Med, Plzen, Czech Republic.
Imai, Yutaka (författare)
Tohoku Univ, Grad Sch Pharmaceut Sci, Sendai, Miyagi, Japan.;Univ Republica, Hosp Clin, Ctr Nefrol, Montevideo, Uruguay.;Univ Republica, Hosp Clin, Dept Fisiopatol, Montevideo, Uruguay.
Wang, Ji-Guang (författare)
Tohoku Univ, Grad Sch Pharmaceut Sci, Sendai, Miyagi, Japan.
O'Brien, Eoin (författare)
Univ Coll Dublin, Conway Inst Biomol & Biomed Res, Dublin, Ireland.
Staessen, Jan A. (författare)
Katholieke Univ Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Studies Coordinating Ctr, Leuven, Belgium.;Maastricht Univ, Dept Epidemiol, Maastricht, Netherlands.
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Univ Calif Irvine, Sch Med, Div Cardiol, Heart Dis Prevent Program, Irvine, CA 92717 USA Katholieke Univ Leuven, Dept Cardiovasc Sci, Res Unit Hypertens & Cardiovasc Epidemiol, Studies Coordinating Ctr, Leuven, Belgium. (creator_code:org_t)
Elsevier BV, 2016
2016
Engelska.
Ingår i: Journal of the American College of Cardiology. - : Elsevier BV. - 0735-1097 .- 1558-3597. ; 68:19, s. 2033-2043
Relaterad länk:
https://doi.org/10.1...
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https://urn.kb.se/re...
https://doi.org/10.1...
http://kipublication...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • BACKGROUND The role of white-coat hypertension (WCH) and the white-coat-effect (WCE) in development of cardiovascular disease (CVD) risk remains poorly understood. OBJECTIVES Using data from the population-based, 11-cohort IDACO (International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes), this study compared daytime ambulatory blood pressure monitoring with conventional blood pressure measurements in 653 untreated subjects with WCH and 653 normotensive control subjects. METHODS European Society Hypertension guidelines were used as a 5-stage risk score. Low risk was defined as 0 to 2 risk factors, and high risk was defined as >= 3 to 5 risk factors, diabetes, and/or history of prior CVD events. Age-and cohort-matching was done between 653 untreated subjects with WCH and 653 normotensive control subjects. RESULTS In a stepwise linear regression model, systolic WCE increased by 3.8 mm Hg (95% confidence interval [CI]: 3.1 to 4.6 mm Hg) per 10-year increase in age, and was similar in low-and high-risk subjects with or without prior CVD events. Over a median 10.6-year follow-up, incidence of new CVD events was higher in 159 high-risk subjects with WCH compared with 159 cohort-and age-matched high-risk normotensive subjects (adjusted hazard ratio [HR]: 2.06; 95% CI: 1.10 to 3.84; p = 0.023). The HR was not significant for 494 participants with low-risk WCH and age-matched low-risk normotensive subjects. Subgroup analysis by age showed that an association between WCH and incident CVD events is limited to older (age >= 60 years) high-risk WCH subjects; the adjusted HR was 2.19 (95% CI: 1.09 to 4.37; p = 0.027) in the older high-risk group and 0.88 (95% CI: 0.51 to 1.53; p = 0.66) in the older low-risk group (p for interaction = 0.044). CONCLUSIONS WCE size is related to aging, not to CVD risk. CVD risk in most persons with WCH is comparable to age-and risk-adjusted normotensive control subjects.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

ambulatory blood pressure monitoring
cardiovascular disease
epidemiology
white-coat effect

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