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Sex differences in ...
Sex differences in depression during pregnancy and the postpartum period
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- Sundström Poromaa, Inger (författare)
- Uppsala universitet,Obstetrik & gynekologi
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- Comasco, Erika (författare)
- Uppsala universitet,Institutionen för neurovetenskap,Neuropsychopharmacology
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- Georgakis, Marios K. (författare)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, Athens, Greece
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- Skalkidou, Alkistis (författare)
- Uppsala universitet,Obstetrik & gynekologi
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(creator_code:org_t)
- 2016-11-07
- 2017
- Engelska.
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Ingår i: Journal of Neuroscience Research. - : Wiley. - 0360-4012 .- 1097-4547. ; 95:1-2, s. 719-730
- Relaterad länk:
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https://uu.diva-port... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Women have a lifetime risk of major depression double that of men but only during their reproductive years. This sex difference has been attributed partially to activational effects of female sex steroids and also to the burdens of pregnancy, childbirth, and parenting. Men, in contrast, have a reproductive period difficult to delineate, and research on the mental health of men has rarely considered the effects of fatherhood. However, the couple goes through a number of potentially stressing events during the reproductive period, and both mothers and fathers are at risk of developing peripartum depression. This Review discusses the literature on maternal and paternal depression and the endocrine changes that may predispose a person to depression at this stage of life, with specific focus on the hypothalamus-pituitary axis, oxytocin, and testosterone levels in men. Important findings on sex differences in the neural correlates of maternal and paternal behavior have emerged, highlighting the relevance of the emotional brain in mothers and the sociocognitive brain in fathers and pointing toward the presence of a common parents' brain. Additionally, sex differences in neurogenesis and brain plasticity are described in relation to peripartum depression.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- peripartum depression
- sex
- testosterone
- cortisol
- oxytocin
- neuroimaging
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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