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  • Janson, ChristerUppsala universitet,Lung- allergi- och sömnforskning (författare)

Health care resource utilization and cost for asthma patients regularly treated with oral corticosteroids - a Swedish observational cohort study (PACEHR)

  • Artikel/kapitelEngelska2018

Förlag, utgivningsår, omfång ...

  • 2018-09-03
  • BMC,2018
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-364248
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-364248URI
  • https://doi.org/10.1186/s12931-018-0855-3DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:139086112URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Background: Patients with severe uncontrolled asthma may receive oral corticosteroid (OCS) treatment regularly. The present study investigated the health care resource utilization and cost in regularly OCS treated Swedish asthma patients.Methods: Primary care medical records data were linked to data from Swedish national health registries. Patients >= 18 years with a drug claim for obstructive pulmonary diseases during 2007-2009 (index date) and a prior asthma diagnosis, were classified by their OCS claims during the 12-months' post index period: regular OCS equals >= 5 mg per day; periodic OCS less than 5 mg per day; or non-OCS users. Cost of asthma-and OCS-morbidity-related health care resource utilization were calculated.Results: A total of 15,437 asthma patients (mean age 47.8, female 62.6%), whereof 223 (1.44%) were regular OCS users, 3054 (19.7%) were periodic, and 12,160 (78.7%) were non-OCS users. Regular OCS users were older and more often females, had lower lung function, greater eosinophil count and more co-morbidities at baseline compared with the other groups. Age-adjusted annual total health care cost was three-times greater in the regular OCS group ((sic)5615) compared with the non-OCS users ((SIC) 1980) and twice as high as in the periodic OCS group ((sic) 2948). The major cost driver in the non-OCS and periodic OCS groups were primary care consultations, whereas inpatient costs were the major cost driver in the regular OCS group. The asthma related costs represented 10-12% of the total cost in all three groups.Conclusion: In this real-life asthma study in Sweden, the total yearly cost of health care resource utilization for a regular OCS user was three times greater than for a patient with no OCS use, indicating substantial economic and health care burden for asthma patients on regular oral steroid treatment.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Lisspers, Karin,Docent,1954-Uppsala universitet,Allmänmedicin och preventivmedicin(Swepub:uu)kalis120 (författare)
  • Ställberg, Björn,DocentUppsala universitet,Allmänmedicin och preventivmedicin(Swepub:uu)bjsta623 (författare)
  • Johansson, GunnarUppsala universitet,Allmänmedicin och preventivmedicin(Swepub:uu)gunnarjs (författare)
  • Telg, GunillaAstraZeneca Nord Baltic, Sodertalje, Sweden (författare)
  • Thuresson, MarcusStatisticon AB, Uppsala, Sweden (författare)
  • Christensen, Helene NordahlAstraZeneca Nord Baltic, Sodertalje, Sweden (författare)
  • Larsson, KjellKarolinska Institutet,Karolinska Inst, Natl Inst Environm Med, Solna, Sweden (författare)
  • Uppsala universitetLung- allergi- och sömnforskning (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Respiratory Research: BMC191465-99211465-993X

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