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Rare and low-freque...
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Marouli, EiriniQueen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.,Queen Mary University
(author)
Rare and low-frequency coding variants alter human adult height
- Article/chapterEnglish2017
Publisher, publication year, extent ...
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2017-02-01
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Springer Science and Business Media LLC,2017
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-317947
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-317947URI
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https://doi.org/10.1038/nature21039DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-132627URI
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https://lup.lub.lu.se/record/3afab246-fd00-4522-a319-c310adf7315fURI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencies (in the range of 0.1-4.8%) and effects of up to 2 centimetres per allele (such as those in IHH, STC2, AR and CRISPLD2), greater than ten times the average effect of common variants. In functional follow-up studies, rare height increasing alleles of STC2 (giving an increase of 1-2 centimetres per allele) compromised proteolytic inhibition of PAPP-A and increased cleavage of IGFBP-4 in vitro, resulting in higher bioavailability of insulin-like growth factors. These 83 height-associated variants overlap genes that are mutated in monogenic growth disorders and highlight new biological candidates (such as ADAMTS3, IL11RA and NOX4) and pathways (such as proteoglycan and glycosaminoglycan synthesis) involved in growth. Our results demonstrate that sufficiently large sample sizes can uncover rare and low-frequency variants of moderate-to-large effect associated with polygenic human phenotypes, and that these variants implicate relevant genes and pathways.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Graff, MariaelisaUniv N Carolina, Dept Epidemiol, Chapel Hill, NC 27514 USA.,North Carolina State University
(author)
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Medina-Gomez, CarolinaErasmus Sch Ctr, Dept Epidemiol, NL-3015 GE Rotterdam, Netherlands.;Erasmus Sch Ctr, Dept Internal Med, NL-3015 GE Rotterdam, Netherlands.,Erasmus University Medical Center
(author)
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Lo, Ken SinMontreal Heart Inst, Montreal, PQ H1T 1C8, Canada.,Montreal Heart Institute
(author)
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Wood, Andrew R.Univ Exeter, Sch Med, Genet Complex Traits, Exeter EX2 5DW, Devon, England.,University of Exeter
(author)
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Kjaer, Troels R.Aarhus Univ, Dept Mol Biol & Genet, DK-8000 Aarhus, Denmark.,Aarhus University
(author)
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Fine, Rebecca S.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Boston Childrens Hosp, Div Endocrinol, Boston, MA 02115 USA.;Boston Childrens Hosp, Ctr Basic & Translat Obes Res, Boston, MA 02115 USA.,Boston Children's Hospital
(author)
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Lu, YingchangVanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA.;Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10069 USA.,Icahn School of Medicine at Mount Sinai
(author)
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Schurmann, ClaudiaIcahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10069 USA.,Icahn School of Medicine at Mount Sinai
(author)
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Highland, Heather M.Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27514 USA.;Univ Texas Hlth Sci Ctr Houston, Univ Texas Grad Sch Biomed Sci Houston, Univ Texas Sch Publ Hlth, Ctr Human Genet, Houston, TX 77030 USA.,University of Texas
(author)
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Rueger, SinaUniv Lausanne Hosp, Inst Social & Prevent Med, CH-1010 Lausanne, Switzerland.;Swiss Inst Bioinformat, CH-1015 Lausanne, Switzerland.,Swiss Institute for Bioinformatics (SIB)
(author)
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Thorleifsson, GudmardeCODE Genet Amgen Inc, IS-101 Reykjavik, Iceland.,deCODE Genetics
(author)
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Justice, Anne E.Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27514 USA.,North Carolina State University
(author)
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Lamparter, DavidSwiss Inst Bioinformat, CH-1015 Lausanne, Switzerland.;Univ Lausanne, Dept Comp Biol, CH-1011 Lausanne, Switzerland.,University of Lausanne
(author)
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Stirrups, Kathleen E.Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.;Univ Cambridge, Dept Hematol, Cambridge CB2 0PT, England.,University of Cambridge
(author)
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Turcot, ValerieMontreal Heart Inst, Montreal, PQ H1T 1C8, Canada.,Montreal Heart Institute
(author)
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Young, Kristin L.Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27514 USA.,North Carolina State University
(author)
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Winkler, Thomas W.Univ Regensburg, Dept Genet Epidemiol, D-93051 Regensburg, Germany.,University of Regensburg
(author)
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Esko, TonuBroad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Boston Childrens Hosp, Div Endocrinol, Boston, MA 02115 USA.;Boston Childrens Hosp, Ctr Basic & Translat Obes Res, Boston, MA 02115 USA.;Univ Tartu, Estonian Genome Ctr, EE-51010 Tartu, Estonia.,Tartu University Hospital
(author)
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Karaderi, TugceUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.,University of Oxford
(author)
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Locke, Adam E.Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Washington Univ, Sch Med, McDonnell Genome Inst, St Louis, MO 63108 USA.,University of Washington
(author)
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Masca, Nicholas G. D.Univ Leicester, Glenfield Hosp, Dept Cardiovasc Sci, Leicester LE3 9QP, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester LE3 9QP, Leics, England.,Glenfield Hospital
(author)
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Ng, Maggie C. Y.Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC 27157 USA.;Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC 27157 USA.,Wake Forest University
(author)
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Mudgal, PoorvaWake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC 27157 USA.,Wake Forest University
(author)
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Rivas, Manuel A.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Nuffield Dept Clin Med, Oxford OX3 7BN, England.,University of Oxford
(author)
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Vedantam, SailajaBroad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Harvard Med Sch, Dept Genet, Boston, MA 02115 USA.;Boston Childrens Hosp, Div Endocrinol, Boston, MA 02115 USA.;Boston Childrens Hosp, Ctr Basic & Translat Obes Res, Boston, MA 02115 USA.,Boston Children's Hospital
(author)
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Mahajan, AnubhaUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.,University of Oxford
(author)
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Guo, XiuqingLABioMed Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90502 USA.,Harbor–UCLA Medical Center
(author)
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Abecasis, GoncaloUniv Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.,Michigan Technological University
(author)
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Aben, Katja K.Netherland Comprehens Canc Org, NL-3501 DB Utrecht, Netherlands.;Radboud Univ Nijmegen, Med Ctr, NL-6500 HB Nijmegen, Netherlands.,Radboud University Medical Center
(author)
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Adair, Linda S.Univ N Carolina, Dept Nutr, Chapel Hill, NC 27599 USA.,North Carolina State University
(author)
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Alam, Dewan S.Ctr Control Chron Dis, Dhaka 1212, Bangladesh.,Centre for Control of Chronic Diseases (CCCD)
(author)
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Albrecht, EvaHelmholtz Zentrum Munchen German Res Ctr Environm, Inst Genet Epidemiol, D-85764 Neuherberg, Germany.
(author)
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Allin, Kristine H.Univ Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.,Hagedorn Research Institute, Copenhagen University
(author)
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Allison, MatthewUniv Calif San Diego, Dept Family Med & Publ Hlth, La Jolla, CA 92093 USA.,San Diego State University
(author)
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Amouyel, PhilippeINSERM, U1167, F-59019 Lille, France.;Inst Pasteur, U1167, F-59019 Lille, France.;Univ Lille, U1167, RID AGE Risk Factors & Mol Determinants Aging Rel, F-59019 Lille, France.,Lille 2 University
(author)
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Appel, Emil V.Univ Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.,Hagedorn Research Institute, Copenhagen University
(author)
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Arveiler, DominiqueUniv Strasbourg, Dept Epidemiol & Publ Hlth, F-67085 Strasbourg, France.;Univ Hosp Strasbourg, Dept Publ Hlth, F-67081 Strasbourg, France.,University Hospital Of Strasbourg
(author)
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Asselbergs, Folkert W.Univ Med Ctr Utrecht, Dept Cardiol, Div Heart & Lungs, Utrecht, Netherlands.;ICIN Netherland Heart Inst, Durrer Ctr Cardiogenet Res, Utrecht, Netherlands.;UCL, Fac Populat Hlth Sci, Inst Cardiovasc Sci, London, England.,University College London
(author)
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Auer, Paul L.Univ Wisconsin, Zilber Sch Publ Hlth, Milwaukee, WI 53201 USA.,University of Wisconsin-Milwaukee
(author)
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Balkau, BeverleyINSERM, Ctr Rech Epidemiol & Sante Populat CESP, U1018, Villejuif, France.,Centre for Research in Epidemiology and Population Health (CESP)
(author)
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Banas, BernhardUniv Hosp Regensburg, Dept Nephrol, D-93042 Regensburg, Germany.,University Hospital Regensburg
(author)
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Bang, Lia E.Copenhagen Univ Hosp, Rigshosp, Dept Cardiol, DK-2100 Copenhagen, Denmark.,Copenhagen University Hospital
(author)
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Benn, MarianneCopenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2730 Herlev, Denmark.;Univ Copenhagen, Fac Med & Hlth Sci, DK-2200 Copenhagen, Denmark.,Hagedorn Research Institute, Copenhagen University
(author)
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Bergmann, SvenSwiss Inst Bioinformat, CH-1015 Lausanne, Switzerland.;Univ Lausanne, Dept Comp Biol, CH-1011 Lausanne, Switzerland.,University of Lausanne
(author)
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Bielak, Lawrence F.Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA.,Michigan Technological University
(author)
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Blueher, MatthiasUniv Leipzig, Dept Med, D-04103 Leipzig, Germany.,Leipzig University
(author)
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Boeing, HeinerGerman Inst Human Nutr Potsdam Rehbruecke DIfE, Dept Epidemiol, D-14558 Nuthetal, Germany.
(author)
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Boerwinkle, EricUniv Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Ctr Human Genet, Houston, TX 77030 USA.;Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA.
(author)
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Boeger, Carsten A.Univ Hosp Regensburg, Dept Nephrol, D-93042 Regensburg, Germany.
(author)
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Bonnycastle, Lori L.NHGRI, Med Genom & Metabol Genet Branch, NIH, Bethesda, MD 20892 USA.
(author)
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Bork-Jensen, JetteUniv Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.
(author)
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Bots, Michiel L.Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.
(author)
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Bottinger, Erwin P.Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.
(author)
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Bowden, Donald W.Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC 27157 USA.;Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC 27157 USA.;Wake Forest Sch Med, Dept Biochem, Winston Salem, NC 27157 USA.
(author)
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Brandslund, IvanLillebaelt Hosp, Dept Clin Biochem, DK-7100 Vejle, Denmark.;Univ Southern Denmark, Inst Reg Hlth Res, DK-5000 Odense, Denmark.
(author)
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Breen, GeromeKings Coll London, Inst Psychiat Psychol & Neurosci, MRC Social Genet & Dev Psychiat Ctr, London SE5 8AF, England.;NIHR Biomed Res Ctr Mental Hlth Maudsley, London SE5 8AF, England.
(author)
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Brilliant, Murray H.Marshfield Clin Res Fdn, Marshfield, WI 54449 USA.
(author)
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Broer, LindaErasmus Sch Ctr, Dept Internal Med, NL-3015 GE Rotterdam, Netherlands.
(author)
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Burt, Amber A.Univ Washington, Dept Med, Seattle, WA 98195 USA.
(author)
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Butterworth, Adam S.Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.;Univ Cambridge, NIHR Blood & Transplant Res Unit Donor Hlth Genom, Cambridge CB1 8RN, England.
(author)
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Carey, David J.Sigfried & Janet Weis Ctr Res, Danville, PA 17822 USA.
(author)
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Caulfield, Mark J.Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.;Queen Mary Univ, Barts & London Sch Med & Dent, NIHR Barts Cardiovasc Res Unit, London EC1M 6BQ, England.
(author)
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Chambers, John C.London North West Healthcare NHS Trust, Ealing Hosp, Dept Cardiol, Middlesex UB1 3HW, England.;Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London W2 1PG, England.;Univ London Imperial Coll Sci Technol & Med, Healthcare NHS Trust, London W12 0HS, England.
(author)
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Chasman, Daniel I.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Brigham & Womens Hosp, Div Genet, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Brigham & Womens & Harvard Med Sch, Div Prevent Med, Boston, MA 02115 USA.
(author)
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Chen, Yii-Der IdaLABioMed Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90502 USA.
(author)
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Chowdhury, RajivUniv Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.
(author)
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Christensen, CramerLillebaelt Hosp, Dept Med, DK-7100 Vejle, Denmark.
(author)
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Chu, Audrey Y.Brigham & Womens & Harvard Med Sch, Div Prevent Med, Boston, MA 02115 USA.;NHLBI, Framingham Heart Study, Framingham, MA 01702 USA.
(author)
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Cocca, MassimilianoUniv Trieste, Dept Med Surg & Hlth Sci, I-34100 Trieste, Italy.
(author)
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Collins, Francis S.NHGRI, Med Genom & Metabol Genet Branch, NIH, Bethesda, MD 20892 USA.
(author)
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Cook, James P.Univ Liverpool, Dept Biostat, Liverpool L69 3GL, Merseyside, England.
(author)
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Corley, JanieUniv Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, 7 George Sq, Edinburgh EH8 9JZ, Midlothian, Scotland.
(author)
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Galbany, Jordi CorominasRadboud Univ Nijmegen, Med Ctr, Dept Human Genet, NL-6500 HB Nijmegen, Netherlands.
(author)
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Cox, Amanda J.Wake Forest Sch Med, Ctr Diabet Res, Winston Salem, NC 27157 USA.;Wake Forest Sch Med, Ctr Genom & Personalized Med Res, Winston Salem, NC 27157 USA.;Griffith Univ, Menzies Hlth Inst Queensland, Southport, Qld, Australia.
(author)
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Cuellar-Partida, GabrielUniv Queensland, Diamantina Inst, Brisbane, Qld 4072, Australia.;QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia.
(author)
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Danesh, JohnUniv Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.;Univ Cambridge, NIHR Blood & Transplant Res Unit Donor Hlth Genom, Cambridge CB1 8RN, England.;Wellcome Trust Sanger Inst, Wellcome Genome Campus, Cambridge CB10 1SA, England.;Univ Cambridge, Dept Med, Cambridge Escellence, British Heart Fdn, Cambridge CB2 0QQ, England.
(author)
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Davies, GailUniv Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, 7 George Sq, Edinburgh EH8 9JZ, Midlothian, Scotland.
(author)
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de Bakker, Paul I. W.Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands.;Univ Med Ctr Utrecht, Ctr Mol Med, Dept Genet, NL-3584 CX Utrecht, Netherlands.
(author)
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de Borst, Gert J.Univ Med Ctr Utrecht, Dept Vasc Surg, Div Surg Specialties, NL-3584 CX Utrecht, Netherlands.
(author)
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de Denus, SimonMontreal Heart Inst, Montreal, PQ H1T 1C8, Canada.;Univ Montreal, Fac Pharm, Montreal, PQ H3T 1J4, Canada.
(author)
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de Groot, Mark C. H.Univ Med Ctr Utrecht, Div Lab & Pharm, Dept Clin Chem & Haematol, NL-3508 GA Utrecht, Netherlands.;Univ Utrecht, Div Pharmacoepidemiol & Clin Pharmacol, Utrecht Inst Pharmaceut Sci, NL-3508 TB Utrecht, Netherlands.
(author)
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de Mutsert, ReneeLeiden Univ, Med Ctr, Dept Clin Epidemiol, NL-2300 RC Leiden, Netherlands.
(author)
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Deary, Ian J.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, 7 George Sq, Edinburgh EH8 9JZ, Midlothian, Scotland.
(author)
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Dedoussis, GeorgeHarokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens 17671, Greece.
(author)
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Demerath, Ellen W.Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN 55454 USA.
(author)
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den Hollander, Anneke I.Radbound Univ Med Ctr, Dept Ophthalmol, NL-6500 HB Nijmegen, Netherlands.
(author)
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Dennis, Joe G.Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England.
(author)
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Di Angelantonio, EmanueleUniv Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.;Univ Cambridge, NIHR Blood & Transplant Res Unit Donor Hlth Genom, Cambridge CB1 8RN, England.
(author)
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Drenos, FotiosUCL, Inst Cardiovasc Sci, London WC1E 6JF, England.;Univ Bristol, Sch Social & Community Med, MRC Integrat Epidemiol Unit, Bristol BS8 2BN, Avon, England.
(author)
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Du, MengmengFred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98109 USA.;Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10017 USA.
(author)
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Dunning, Alison M.Univ Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England.;Univ Helsinki, Inst Mol Med Finland FIMM, FI-00014 Helsinki, Finland.
(author)
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Easton, Douglas F.Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England.;Univ Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England.
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Ebeling, TapaniOulu Univ Hosp, Dept Med, Oulu 90029, Finland.;Univ Oulu, Res Unit Internal Med, FI-90014 Oulu, Finland.
(author)
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Edwards, Todd L.Vanderbilt Univ, Vanderbilt Genet Inst, Inst Med & Publ Hlth, Dept Med,Div Epidemiol, Nashville, TN 37203 USA.
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Ellinor, Patrick T.Massachusetts Gen Hosp, Boston, MA 02114 USA.;Broad Inst, Med & Populat Genet Program, Cambridge, MA 02141 USA.
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Elliott, PaulUniv London Imperial Coll Sci Technol & Med, Sch Publ Hlth, MRC PHE Ctr Environm & Hlth, Dept Epidemiol & Biostat, London W2 1PG, England.
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Evangelou, EvangelosUniv London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London W2 1PG, England.;Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, GR-45110 Ioannina, Greece.
(author)
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Farmaki, Aliki-EleniHarokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens 17671, Greece.
(author)
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Faul, Jessica D.Univ Michigan, Inst Social Res, Survey Res Ctr, Ann Arbor, MI 48104 USA.
(author)
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Feitosa, Mary F.Washington Univ, Sch Med, Dept Genet, Div Stat Genom, St Louis, MO 63108 USA.
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Feng, ShuangUniv Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.
(author)
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Ferrannini, EleCNR Inst Clin Physiol, Pisa, Italy.;Univ Pisa, Dept Clin & Expt Med, Pisa, Italy.
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Ferrario, Marco M.Univ Insubria, Dept Clin & Expt Med, Res Ctr Epidemiol & Prevent Med, I-21100 Varese, Italy.
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Ferrieres, JeanToulouse Univ, Sch Med, F-31059 Toulouse, France.
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Florez, Jose C.Massachusetts Gen Hosp, Boston, MA 02114 USA.;Broad Inst, Med & Populat Genet Program, Cambridge, MA 02141 USA.;Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA.
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Ford, IanUniv Glasgow, Glasgow G12 8QQ, Lanark, Scotland.
(author)
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Fornage, MyriamUniv Texas Hlth Sci Ctr Houston, Inst Mol Med, Houston, TX 77030 USA.
(author)
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Franks, Paul W.Umeå University,Lund University,Lunds universitet,Umeå universitet,Medicin,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Harvard University(Swepub:lu)med-plf
(author)
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Frikke-Schmidt, RuthUniv Copenhagen, Fac Med & Hlth Sci, DK-2200 Copenhagen, Denmark.;Copenhagen Univ Hosp, Rigshosp, Dept Clin Biochem, DK-2100 Copenhagen, Denmark.
(author)
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Galesloot, Tessel E.Radboud Univ Nijmegen, Med Ctr, NL-6500 HB Nijmegen, Netherlands.
(author)
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Gan, WeiUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.
(author)
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Gandin, IlariaUniv Trieste, Dept Med Sci, I-34137 Trieste, Italy.
(author)
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Gasparini, PaoloUniv Trieste, Dept Med Sci, I-34137 Trieste, Italy.;Sidra Med & Res Ctr, Div Expt Genet, Doha 26999, Qatar.
(author)
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Giedraitis, VilmantasUppsala universitet,Geriatrik(Swepub:uu)vigie517
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Giri, AyushVanderbilt Univ, Vanderbilt Genet Inst, Inst Med & Publ Hlth, Dept Med,Div Epidemiol, Nashville, TN 37203 USA.
(author)
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Girotto, GiorgiaUniv Trieste, Dept Med Sci, I-34137 Trieste, Italy.;Sidra Med & Res Ctr, Div Expt Genet, Doha 26999, Qatar.
(author)
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Gordon, Scott D.QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia.
(author)
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Gordon-Larsen, PennyUniv N Carolina, Caroline Populat Ctr, Chapel Hill, NC 27514 USA.;Univ N Carolina, Dept Nutr, Gillings Sch Global Publ Hlth, Chapel Hill, NC 27514 USA.
(author)
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Gorski, MathiasUniv Regensburg, Dept Genet Epidemiol, D-93051 Regensburg, Germany.;Univ Hosp Regensburg, Dept Nephrol, D-93042 Regensburg, Germany.;Univ Leipzig, IFB Adipos Dis, D-04103 Leipzig, Germany.
(author)
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Grarup, NielsUniv Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.
(author)
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Grove, Megan L.Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Ctr Human Genet, Houston, TX 77030 USA.
(author)
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Gudnason, VilmundurUniv Iceland, Fac Med, IS-101 Reykjavik, Iceland.;Icelandic Heart Assoc, IS-201 Kopavogur, Iceland.
(author)
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Gustafsson, StefanUppsala universitet,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi(Swepub:uu)stegu732
(author)
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Hansen, TorbenUniv Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.
(author)
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Harris, Kathleen MullanUniv N Carolina, Caroline Populat Ctr, Chapel Hill, NC 27514 USA.;Univ N Carolina, Dept Sociol, Chapel Hill, NC 27514 USA.
(author)
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Harris, Tamara B.NIA, Lab Epidemiol & Populat Sci, Intramural Res Program, NIH, Bethesda, MD 20892 USA.
(author)
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Hattersley, Andrew T.Univ Exeter, Univ Exeter Med Sch, Exeter EX2 5DW, Devon, England.
(author)
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Hayward, CarolineUniv Edinburgh, Inst Genet & Mol Med, MRCHGU, Edinburgh EH4 2XU, Midlothian, Scotland.
(author)
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He, LiangDuke Univ, Social Sci Res Inst, Biodemog Aging Res Unit, Durham, NC 27708 USA.;Univ Helsinki, Dept Publ Hlth, FI-00014 Helsinki, Finland.
(author)
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Heid, Iris M.Univ Regensburg, Dept Genet Epidemiol, D-93051 Regensburg, Germany.;Helmholtz Zentrum Munchen German Res Ctr Environm, Inst Genet Epidemiol, D-85764 Neuherberg, Germany.
(author)
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Heikkila, KaukoUniv Helsinki, Dept Publ Hlth, FI-00014 Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland FIMM, FI-00014 Helsinki, Finland.
(author)
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Helgeland, OyvindHaukeland Hosp, Dept Pediat, N-5021 Bergen, Norway.;Univ Bergen, Dept Clin Sci, KG Jebson Ctr Diabet Res, N-5020 Bergen, Norway.
(author)
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Hernesniemi, JussiTampere Univ Hosp, Dept Cardiol, Ctr Heart, FI-33521 Tampere, Finland.;Fimlab Labs, Dept Clin Chem, Tampere 33520, Finland.;Univ Tampere, Sch Med, Dept Clin Chem, Tampere 33014, Finland.
(author)
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Hewitt, Alex W.Univ Melbourne, Royal Victorian Eye & Ear Hosp, Ctr Eye Res Australia, Melbourne, Vic 3002, Australia.;Univ Western Australia, Lions Eye Inst, Ctr Ophthalmol & Vis Sci, Perth, WA 6009, Australia.;Univ Tasmania, Menzies Res Inst Tasmania, Hobart, Tas 7000, Australia.
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Hocking, Lynne J.Univ Edinburgh, Ctr Genom & Expt Med, Generat Scotland, Edinburgh EH4 2XU, Midlothian, Scotland.;Univ Aberdeen, Div Appl Med, Musculoskeletal Res Programme, Aberdeen AB25 2ZD, Scotland.
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Hollensted, MetteUniv Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.
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Holmen, Oddgeir L.Norwegian Univ Sci & Technol, NTNU, Dept Publ Hlth, KG Jebsen Ctr Genet Epidemiol, N-7600 Trondheim, Norway.
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Howson, Joanna M. M.Univ Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.
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Hoyng, Carel B.Radbound Univ Med Ctr, Dept Ophthalmol, NL-6500 HB Nijmegen, Netherlands.
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Hveem, KristianNorwegian Univ Sci & Technol, Dept Publ Hlth & Gen Practice, HUNT Res Ctr, N-7600 Levanger, Norway.
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Ikram, M. ArfanErasmus Sch Ctr, Dept Epidemiol, NL-3015 GE Rotterdam, Netherlands.;Erasmus Sch Ctr, Dept Neurol, NL-3015 GE Rotterdam, Netherlands.;Erasmus Sch Ctr, Dept Radiol, NL-3015 GE Rotterdam, Netherlands.
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Ingelsson, ErikUppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)ering425
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Jansson, Jan-HåkanUmeå universitet,Medicin(Swepub:umu)jaja0006
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Jensen, Gorm B.Frederiksberg Univ Hosp, Copenhagen City Heart Study, DK-2000 Frederiksberg, Denmark.
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Jiang, XuejuanUniv Calif Los Angeles, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90089 USA.;Univ Southern Calif, Keck Sch Med, Dept Ophthalmol, USC Roski Eye Inst, Los Angeles, CA 90089 USA.
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Johansson, StefanUniv Bergen, Dept Clin Sci, KG Jebson Ctr Diabet Res, N-5020 Bergen, Norway.;Haukeland Hosp, Ctr Med Genet & Mol Med, N-5021 Bergen, Norway.
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Jorgensen, TorbenUniv Copenhagen, Fac Med & Hlth Sci, DK-2200 Copenhagen, Denmark.;Aalborg Hosp, DK-9000 Aalborg, Denmark.;Capital Reg Denmark, Res Ctr Prevent & Hlth, DK-2600 Glostrup, Denmark.
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Kahali, BratatiUniv Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA.;Univ Michigan, Div Gastroenterol, Ann Arbor, MI 48109 USA.
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Kahn, Rene S.Ctr Med Univ Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, NL-3584 CG Utrecht, Netherlands.
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Kamstrup, Pia R.Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2730 Herlev, Denmark.
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Kanoni, StavroulaQueen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.
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Kaprio, JaakkoUniv Helsinki, Dept Publ Hlth, FI-00014 Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland FIMM, FI-00014 Helsinki, Finland.;Natl Inst Hlth & Welf, FI-00271 Helsinki, Finland.
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Kluivers, Kirsten B.Radboud Univ Nijmegen, Med Ctr, NL-6500 HB Nijmegen, Netherlands.
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Komulainen, PirjoKuopio Res Inst Exercise Med, Fdn Res Hlth Exercise & Nutr, Kuopio 70100, Finland.
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Kooperberg, CharlesFred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98109 USA.
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Kovacs, PeterUniv Leipzig, IFB Adipos Dis, D-04103 Leipzig, Germany.
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Kriebel, JenniferGerman Ctr Diabet Res, D-85764 Munich, Germany.;Helmholtz Zentrum Munchen German Res Ctr Environm, Inst Epidemiol 2, D-85764 Neuherberg, Germany.;Helmholtz Zentrum Munchen German Res Ctr Environm, Res Unit Mol Epidemiol, D-85764 Neuherberg, Germany.
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Kuivaniemi, HelenaSigfried & Janet Weis Ctr Res, Danville, PA 17822 USA.;Univ Stellenbosch, Fac Med & Hlth Sci, Dept Biomed Sci, Dept Psychiat, ZA-7505 Tygerberg, Western Cape, South Africa.;Univ Stellenbosch, Fac Med & Hlth Sci, Dept Biomed Sci, Div Mol Biol & Human Genet, ZA-7505 Tygerberg, Western Cape, South Africa.
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Kuusisto, JohannaUniv Eastern Finland, Inst Clin Med, Internal Med, Kuopio 70210, Finland.;Kuopio Univ Hosp, SF-70210 Kuopio, Finland.
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Lakka, Timo A.Kuopio Res Inst Exercise Med, Fdn Res Hlth Exercise & Nutr, Kuopio 70100, Finland.;Univ Eastern Finland, Inst Biomed & Physiol, Kuopio 70210, Finland.
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Lange, Ethan M.Univ N Carolina, Dept Genet, Chapel Hill, NC 27514 USA.
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Lehtimaki, TerhoFimlab Labs, Dept Clin Chem, Tampere 33520, Finland.;Univ Tampere, Sch Med, Dept Clin Chem, Tampere 33014, Finland.
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Lophatananon, ArtitayaWarsaw Acad Med & Hosp, Div Hlth Sci, Coventry CV4 7AL, W Midlands, England.
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Luan, Jian'anUniv Cambridge, Sch Clin Med, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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Lubitz, Steven A.Massachusetts Gen Hosp, Boston, MA 02114 USA.;Broad Inst, Med & Populat Genet Program, Cambridge, MA 02141 USA.
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Mackey, David A.Univ Western Australia, Lions Eye Inst, Ctr Ophthalmol & Vis Sci, Perth, WA 6009, Australia.
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Madden, Pamela A. F.Washington Univ, Dept Psychiat, St Louis, MO 63110 USA.
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Manning, Alisa K.Massachusetts Gen Hosp, Boston, MA 02114 USA.;Broad Inst, Med & Populat Genet Program, Cambridge, MA 02141 USA.;Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA.;Kuopio Res Inst Exercise Med, Fdn Res Hlth Exercise & Nutr, Kuopio 70100, Finland.
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Mannisto, SatuNatl Inst Hlth & Welf, FI-00271 Helsinki, Finland.
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Marten, JonathanUniv Edinburgh, Inst Genet & Mol Med, MRCHGU, Edinburgh EH4 2XU, Midlothian, Scotland.
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Martin, Nicholas G.QIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia.
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Mazul, Angela L.Univ N Carolina, Dept Epidemiol, Chapel Hill, NC 27514 USA.
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Meidtner, KarinaGerman Ctr Diabet Res, D-85764 Munich, Germany.;German Inst Human Nutr Potsdam Rehbruecke DIfE, Dept Mol Epidemiol, D-14558 Nuthetal, Germany.
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Metspalu, AndresUniv Tartu, Estonian Genome Ctr, EE-51010 Tartu, Estonia.
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Mitchell, PaulUniv Sydney, Ctr Vis Res, Westmead Millennium Inst Med Res, Sydney, NSW 2022, Australia.;Univ Sydney, Dept Ophthalmol, Sydney, NSW 2022, Australia.
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Mohlke, Karen L.Univ N Carolina, Dept Genet, Chapel Hill, NC 27514 USA.
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Mook-Kanamori, Dennis O.Leiden Univ, Med Ctr, Dept Clin Epidemiol, NL-2300 RC Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Publ Hlth & Primary Care, NL-2300 RC Leiden, Netherlands.
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Morgan, AnnaUniv Trieste, Dept Med Sci, I-34137 Trieste, Italy.
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Morris, Andrew D.Univ Edinburgh, Ctr Global Hlth Res, Ushar Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.
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Morris, Andrew P.Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.;Univ Liverpool, Dept Biostat, Liverpool L69 3GL, Merseyside, England.
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Mueller-Nurasyid, MartinaHelmholtz Zentrum Munchen German Res Ctr Environm, Inst Genet Epidemiol, D-85764 Neuherberg, Germany.;Univ Munich, Dept Med 1, D-81377 Munich, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Munich Heart Alliance, D-80802 Munich, Germany.
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Munroe, Patricia B.Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.;Queen Mary Univ, Barts & London Sch Med & Dent, NIHR Barts Cardiovasc Res Unit, London EC1M 6BQ, England.
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Nalls, Mike A.NIA, Neurogenet Lab, NIH, Bethesda, MD 20892 USA.
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Nauck, MatthiasDZHK German Ctr Cardiovasc Res, Partner Site Greifswald, D-17475 Greifswald, Germany.;Univ Med Greifswald, Inst Clin Chem, D-17475 Greifswald, Germany.;Univ Med Greifswald, Lab Med, D-17475 Greifswald, Germany.
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Nelson, Christopher P.Univ Leicester, Glenfield Hosp, Dept Cardiovasc Sci, Leicester LE3 9QP, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester LE3 9QP, Leics, England.
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Neville, MattUniv Oxford, Radcliffe Dept Med, Oxford Ctr Diabetes Endocrinol & Metab, Oxford OX3 7LE, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford OX3 7LE, England.
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Nielsen, Sune F.Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2730 Herlev, Denmark.;Univ Copenhagen, Fac Med & Hlth Sci, DK-2200 Copenhagen, Denmark.
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Nikus, KjellUniv Tampere, Tampere Univ Hosp, Dept Cardiol, Ctr Heart, Tampere 33521, Finland.;Univ Tampere, Sch Med, Tampere 33521, Finland.
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Njolstad, Pal R.Haukeland Hosp, Dept Pediat, N-5021 Bergen, Norway.;Univ Bergen, Dept Clin Sci, KG Jebson Ctr Diabet Res, N-5020 Bergen, Norway.
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Nordestgaard, Borge G.Copenhagen Univ Hosp, Herlev & Gentofte Hosp, Dept Clin Biochem, DK-2730 Herlev, Denmark.;Univ Copenhagen, Fac Med & Hlth Sci, DK-2200 Copenhagen, Denmark.
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Ntalla, IoannaQueen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.
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Rolandsson, OlovUmeå universitet,Allmänmedicin(Swepub:umu)olro0005
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Oksa, HeikkiTampere Univ Hosp, Dept Med, Tampere 33521, Finland.
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Owen, Katharine R.Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabetes Endocrinol & Metab, Oxford OX3 7LE, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford OX3 7LE, England.
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Packard, Chris J.Univ Glasgow, Glasgow G12 8QQ, Lanark, Scotland.
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Padmanabhan, SandoshUniv Glasgow, Glasgow G12 8QQ, Lanark, Scotland.
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Palmer, Colin N. A.Ninewells Hosp & Med Sch, Med Res Inst, Pat Macpherson Ctr Pharmacogenet & Pharmacogenom, Dundee DD1 9SY, Scotland.
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Pasterkamp, GerardUniv Med Ctr Utrecht, Div Labs & Pharm, Lab Clin Chem & Hematol, NL-3584 CX Utrecht, Netherlands.
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Patel, Aniruddh P.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Massachusetts Gen Hosp, Boston, MA 02114 USA.
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Pattie, AlisonUniv Edinburgh, Dept Psychol, 7 George Sq, Edinburgh EH8 9JZ, Midlothian, Scotland.
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Pedersen, OlufUniv Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.
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Peissig, Peggy L.Marshfield Clin Res Fdn, Marshfield, WI 54449 USA.
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Peloso, Gina M.Massachusetts Gen Hosp, Boston, MA 02114 USA.;Broad Inst, Med & Populat Genet Program, Cambridge, MA 02141 USA.
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Pennell, Craig E.Univ Western Australia, Sch Womens & Infants Hlth, Perth, WA 6009, Australia.
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Perola, MarkusNatl Inst Hlth & Welf, FI-00271 Helsinki, Finland.;Univ Helsinki, Inst Mol Med FIMM, FI-00014 Helsinki, Finland.;Univ Helsinki, Diabet & Obes Res Program, FI-00014 Helsinki, Finland.;Univ Tartu, Estonian Genome Ctr, EE-51010 Tartu, Estonia.
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Perry, James A.Univ Maryland, Sch Med, Dept Med, Program Personalized Med, Baltimore, MD 21201 USA.
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Perry, John R. B.Univ Cambridge, Sch Clin Med, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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Person, Thomas N.Marshfield Clin Res Fdn, Marshfield, WI 54449 USA.
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Pirie, AilithUniv Cambridge, Dept Oncol, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England.
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Polasek, OzrenUniv Edinburgh, Ctr Global Hlth Res, Ushar Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.;Univ Split, Sch Med, Split 21000, Croatia.
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Posthuma, DanielleVrije Univ Amsterdam, Dept Complex Trait Genet, Ctr Neurogenom & Cognit Res, NL-1081 HV Amsterdam, Netherlands.;Vrije Univ Amsterdam Med Ctr, Dept Clin Genet, Neurosci Campus Amsterdam, NL-1081 HV Amsterdam, Netherlands.
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Raitakari, Olli T.Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku 20521, Finland.;Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, FIN-20520 Turku, Finland.
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Rasheed, AsifCtr Noncommunicable Dis, Karachi, Pakistan.
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Rauramaa, RainerKuopio Res Inst Exercise Med, Fdn Res Hlth Exercise & Nutr, Kuopio 70100, Finland.;Kuopio Univ Hosp, Dept Clin Physiol & Nucl Med, SF-70210 Kuopio, Finland.
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Reilly, Dermot F.MRL Merck & Co Inc, Genet & Pharmacogenom, Boston, MA 02115 USA.
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Renstrom, FridaUmeå University,Lund University,Lunds universitet,Umeå universitet,Enheten för biobanksforskning,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups(Swepub:lu)med-frm
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Robertson, NeilUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabetes Endocrinol & Metab, Oxford OX3 7LE, England.
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Robino, AntoniettaInst Maternal & Child Hlth IRCCS Burlo Garofolo, I-34137 Trieste, Italy.
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Rolandsson, OlovUmea Univ, Dept Publ Hlth & Clin Med, SE-90185 Umea, Sweden.;Umea Univ, Unit Family Med, Dept Publ Hlth & Clin Med, S-90185 Umea, Sweden.
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Rudan, IgorUniv Edinburgh, Ctr Global Hlth Res, Ushar Inst Populat Hlth Sci & Informat, Edinburgh EH8 9AG, Midlothian, Scotland.
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Ruth, Katherine S.Univ Exeter, Sch Med, Genet Complex Traits, Exeter EX2 5DW, Devon, England.
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Saleheen, DanishCtr Noncommunicable Dis, Karachi, Pakistan.;Univ Penn, Perelman Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA.
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Salomaa, VeikkoNatl Inst Hlth & Welf, FI-00271 Helsinki, Finland.
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Samani, Nilesh J.Univ Leicester, Glenfield Hosp, Dept Cardiovasc Sci, Leicester LE3 9QP, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester LE3 9QP, Leics, England.
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Sandow, KevinLABioMed Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90502 USA.
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Sapkota, YadavQIMR Berghofer Med Res Inst, Brisbane, Qld 4006, Australia.
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Sattar, NaveedUniv Glasgow, Glasgow G12 8QQ, Lanark, Scotland.
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Schmidt, Marjanka K.Netherlands Canc Inst, Antoni van Leewenhoek Hosp, NL-1066 CX Amsterdam, Netherlands.
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Schreiner, Pamela J.Univ Minnesota, Div Epidemiol & Community Hlth, Minneapolis, MN 55454 USA.
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Schulze, Matthias B.German Ctr Diabet Res, D-85764 Munich, Germany.;German Inst Human Nutr Potsdam Rehbruecke DIfE, Dept Mol Epidemiol, D-14558 Nuthetal, Germany.
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Scott, Robert A.Univ Cambridge, Sch Clin Med, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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Segura-Lepe, Marcelo P.Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London W2 1PG, England.
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Shah, SvatiDuke Univ, Durham, NC 27703 USA.
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Sim, XuelingUniv Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Natl Univ Singapore, Natl Univ Hlth Syst, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.
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Sivapalaratnam, SutheshMassachusetts Gen Hosp, Boston, MA 02114 USA.;Univ Cambridge, Dept Haematol, Cambridge CB2 0PT, England.;AMC, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands.
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Small, Kerrin S.Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.
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Smith, Albert VernonUniv Iceland, Fac Med, IS-101 Reykjavik, Iceland.;Icelandic Heart Assoc, IS-201 Kopavogur, Iceland.
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Smith, Jennifer A.Univ Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA.
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Southam, LorraineUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.;Wellcome Trust Sanger Inst, Wellcome Genome Campus, Cambridge CB10 1SA, England.
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Spector, Timothy D.Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.
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Speliotes, Elizabeth K.Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA.;Univ Michigan, Div Gastroenterol, Ann Arbor, MI 48109 USA.
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Starr, John M.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh EH8 9JZ, Midlothian, Scotland.;Univ Edinburgh, Alzheimer Scotland Dementia Res Ctr, Edinburgh EH8 9JZ, Midlothian, Scotland.
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Steinthorsdottir, ValgerdurdeCODE Genet Amgen Inc, IS-101 Reykjavik, Iceland.
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Stumvoll, MichaelUniv Leipzig, IFB Adipos Dis, D-04103 Leipzig, Germany.;Univ Leipzig, Dept Med, D-04103 Leipzig, Germany.
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Surendran, PraveenUniv Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.
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Tansey, Katherine E.Cardiff Univ, Coll Biomed & Life Sci, Cardiff CF14 4EP, S Glam, Wales.;Univ Bristol, Dept Social & Community Med, MRC Integrat Epidemiol Unit, Bristol BS8 2BN, Avon, England.
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Tardif, Jean-ClaudeMontreal Heart Inst, Montreal, PQ H1T 1C8, Canada.;Univ Montreal, Fac Med, Dept Med, Montreal, PQ H3T 1J4, Canada.
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Taylor, Kent D.LABioMed Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90502 USA.
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Thompson, Deborah J.Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Canc Genet Epidemiol, Cambridge CB1 8RN, England.
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Thorsteinsdottir, UnnurdeCODE Genet Amgen Inc, IS-101 Reykjavik, Iceland.;Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland.
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Thuesen, Betina H.Capital Reg Denmark, Res Ctr Prevent & Hlth, DK-2600 Glostrup, Denmark.
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Tromp, GerardSigfried & Janet Weis Ctr Res, Danville, PA 17822 USA.;Univ Stellenbosch, Fac Med & Hlth Sci, Dept Biomed Sci, Div Human Genet & Mol Biol, ZA-7505 Tygerberg, Western Cape, South Africa.
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Trompet, StellaLeiden Univ Med Ctr, Dept Cardiol, NL-2333 Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Gerontol & Geriatr, NL-2333 Leiden, Netherlands.
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Tsafantakis, EmmanouilAnogia Med Ctr, Anogia, Greece.
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Tuomilehto, JaakkoNatl Inst Hlth & Welf, FI-00271 Helsinki, Finland.;Danube Univ Krems, Ctr Vasc Prevent, A-3500 Krems, Austria.;Dasman Diabet Inst, Dasman 15462, Kuwait.;King Abdulaziz Univ, Diabet Res Grp, Jeddah 21589, Saudi Arabia.
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Tybjaerg-Hansen, AnneUniv Copenhagen, Fac Med & Hlth Sci, DK-2200 Copenhagen, Denmark.;Copenhagen Univ Hosp, Rigshosp, Dept Clin Biochem, DK-2100 Copenhagen, Denmark.
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Uher, RudolfDalhousie Univ, Dept Psychiat, Halifax, NS B3H 4R2, Canada.
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Uitterlinden, Andre G.Erasmus Sch Ctr, Dept Epidemiol, NL-3015 GE Rotterdam, Netherlands.;Erasmus Sch Ctr, Dept Internal Med, NL-3015 GE Rotterdam, Netherlands.
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Varga, Tibor V.Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups(Swepub:lu)med-tv_
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Vitart, VeroniqueUniv Edinburgh, Inst Genet & Mol Med, MRCHGU, Edinburgh EH4 2XU, Midlothian, Scotland.
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Walker, MarkNewcastle Univ, Sch Med, Inst Cellular Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England.
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Wang, FeijieChinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci,Key Lab Nutr & Metab, Shanghai 200031, Peoples R China.
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Wang, YiqinChinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci,Key Lab Nutr & Metab, Shanghai 200031, Peoples R China.
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Wareham, Nicholas J.Univ Cambridge, Sch Clin Med, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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Warren, Helen R.Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.;Queen Mary Univ, Barts & London Sch Med & Dent, NIHR Barts Cardiovasc Res Unit, London EC1M 6BQ, England.
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Wessel, JenniferIndiana Univ, Fairbanks Sch Publ Hlth, Diabet Translat Res Ctr, Dept Epidemiol & Med, Indianapolis, IN 46202 USA.;Indiana Univ, Sch Med, Indianapolis, IN 46202 USA.
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Willems, Sara M.Univ Cambridge, Sch Clin Med, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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Wilson, James G.Univ Mississippi, Med Ctr, Dept Physiol & Biophys, Jackson, MS 39216 USA.
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Witte, Daniel R.Danish Diabet Acad, DK-5000 Odense, Denmark.;Aarhus Univ, Dept Publ Hlth, DK-8000 Aarhus, Denmark.
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Woods, Michael O.Mem Univ Newfoundland, Fac Med, Discipline Genet, St John, NF A1B 3V6, Canada.
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Wu, YingUniv N Carolina, Dept Genet, Chapel Hill, NC 27514 USA.
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Yaghootkar, HaniehUniv Exeter, Sch Med, Genet Complex Traits, Exeter EX2 5DW, Devon, England.
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Yao, JieLABioMed Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90502 USA.
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Yao, PangChinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci,Key Lab Nutr & Metab, Shanghai 200031, Peoples R China.
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Young, RobinUniv Cambridge, Dept Publ Hlth & Primary Care, MRC BHF Cardiovasc Epidemiol Unit, Cambridge CB1 8RN, England.;Univ Glasgow, Glasgow G12 8QQ, Lanark, Scotland.
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Zeggini, EleftheriaWellcome Trust Sanger Inst, Wellcome Genome Campus, Cambridge CB10 1SA, England.
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Zhang, WeihuaLondon North West Healthcare NHS Trust, Ealing Hosp, Dept Cardiol, Middlesex UB1 3HW, England.;Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London W2 1PG, England.
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Zhao, Jing HuaUniv Cambridge, Sch Clin Med, Inst Metab Sci, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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Zhao, WeiUniv Michigan, Sch Publ Hlth, Dept Epidemiol, Ann Arbor, MI 48109 USA.;Univ Penn, Perelman Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA.
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Zheng, HeChinese Acad Sci, Univ Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci,Key Lab Nutr & Metab, Shanghai 200031, Peoples R China.
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Kathiresan, SekarBroad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Harvard Med Sch, Boston, MA 02115 USA.;Massachusetts Gen Hosp, Boston, MA 02114 USA.
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McCarthy, Mark I.Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.;Univ Oxford, Radcliffe Dept Med, Oxford Ctr Diabetes Endocrinol & Metab, Oxford OX3 7LE, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford OX3 7LE, England.
(author)
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Willer, Cristen J.Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA.
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Stefansson, KarideCODE Genet Amgen Inc, IS-101 Reykjavik, Iceland.;Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland.
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Heard-Costa, Nancy L.NHLBI, Framingham Heart Study, Framingham, MA 01702 USA.;Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA.
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Pers, Tune H.Univ Copenhagen, Fac Med & Hlth Sci, Novo Nordisk Fdn Ctr Basic Metab Res, DK-2100 Copenhagen, Denmark.;Statens Serum Inst, Dept Epidemiol Res, DK-2200 Copenhagen, Denmark.
(author)
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Lindgren, Cecilia M.Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.;Univ Oxford, Big Data Inst, Li Ka Shing Ctr Hlth Informat & Discovery, Oxford OX3 7BN, England.
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Oxvig, ClausAarhus Univ, Dept Mol Biol & Genet, DK-8000 Aarhus, Denmark.
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Kutalik, ZoltanUniv Lausanne Hosp, Inst Social & Prevent Med, CH-1010 Lausanne, Switzerland.;Swiss Inst Bioinformat, CH-1015 Lausanne, Switzerland.
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Rivadeneira, FernandoErasmus Sch Ctr, Dept Epidemiol, NL-3015 GE Rotterdam, Netherlands.;Erasmus Sch Ctr, Dept Internal Med, NL-3015 GE Rotterdam, Netherlands.
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Loos, Ruth J. F.Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.;Icahn Sch Med Mt Sinai, Genet Obes & Related Metab Traits Program, New York, NY 10069 USA.;Icahn Sch Med Mt Sinai, Mindich Child Hlth & Dev Inst, New York, NY 10069 USA.
(author)
-
Frayling, Timothy M.Univ Exeter, Sch Med, Genet Complex Traits, Exeter EX2 5DW, Devon, England.
(author)
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Hirschhorn, Joel N.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.;Boston Childrens Hosp, Div Endocrinol, Boston, MA 02115 USA.;Boston Childrens Hosp, Ctr Basic & Translat Obes Res, Boston, MA 02115 USA.;Harvard Med Sch, Dept Pediat & Genet, Boston, MA 02115 USA.
(author)
-
Deloukas, PanosQueen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.;King Abdulaziz Univ, Princess Al Jawhara Al Brahim Ctr Excellence Res, Jeddah 21589, Saudi Arabia.
(author)
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Lettre, GuillaumeMontreal Heart Inst, Montreal, PQ H1T 1C8, Canada.;Univ Montreal, Fac Med, Dept Med, Montreal, PQ H3T 1J4, Canada.
(author)
-
Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.Queen Mary University
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van Schoor, Nata ...
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van Setten, Jess ...
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Varbo, Anette
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Varga, Tibor V.
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Varma, Rohit
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Edwards, Digna R ...
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Vermeulen, Sita ...
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Vestergaard, Hen ...
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Vitart, Veroniqu ...
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Vogt, Thomas F.
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Vozzi, Diego
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Walker, Mark
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Wang, Feijie
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Wang, Carol A.
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Wang, Shuai
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Wang, Yiqin
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Wareham, Nichola ...
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Warren, Helen R.
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Wessel, Jennifer
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Willems, Sara M.
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Wilson, James G.
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Witte, Daniel R.
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Woods, Michael O ...
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Wu, Ying
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Yaghootkar, Hani ...
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Yao, Jie
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Yao, Pang
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Yerges-Armstrong ...
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Young, Robin
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Zeggini, Elefthe ...
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Zhan, Xiaowei
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Zhang, Weihua
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Zhao, Jing Hua
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Zhao, Wei
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Zheng, He
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Zhou, Wei
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Rotter, Jerome I ...
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Boehnke, Michael
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Kathiresan, Seka ...
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McCarthy, Mark I ...
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Willer, Cristen ...
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Stefansson, Kari
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Borecki, Ingrid ...
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Liu, Dajiang J.
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North, Kari E.
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Heard-Costa, Nan ...
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Pers, Tune H.
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Lindgren, Cecili ...
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Oxvig, Claus
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Kutalik, Zoltan
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Rivadeneira, Fer ...
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Loos, Ruth J. F.
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Frayling, Timoth ...
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Hirschhorn, Joel ...
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Deloukas, Panos
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Lettre, Guillaum ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Genetics
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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- Articles in the publication
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Nature
- By the university
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Uppsala University
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Umeå University
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Lund University