WFRF:(Zoi K.)
Sökning: WFRF:(Zoi K.) > Expression of sex s...
- Ekenros, L.Karolinska Institutet (författare)
Expression of sex steroid hormone receptors in human skeletal muscle during the menstrual cycle
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
- 2016-08-09
- WILEY-BLACKWELL,2017
- printrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:uu-319102
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-319102URI
- https://doi.org/10.1111/apha.12757DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:135189731URI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- Aim: Variations in sex hormone levels during the menstrual cycle may affect neuromuscular performance and the risk of sustaining musculoskeletal injury in women. The aim of this study was to investigate mRNA and protein levels for sex steroid hormone receptors in skeletal muscle in three distinct phases of the menstrual cycle. Methods: Fifteen, healthy women with regular menstrual cycles participated in the study. Muscle biopsies from the vastus lateralis were obtained in three hormonally verified phases of the menstrual cycle for each individual, that is the follicular phase, the ovulatory phase and the luteal phase. mRNA and protein levels of oestrogen (ER and ER), progesterone (PR) and androgen (AR) receptors were analysed. Results: There was an overall significant variation in mRNA and protein levels of ER and PR across the menstrual cycle. mRNA and protein levels of ER were highest in the follicular phase when oestradiol levels were low, whereas protein levels of PR were highest in the luteal phase when progesterone levels were high. mRNA levels of PR were highest in the ovulatory phase. No significant variation in AR levels was detected across the menstrual cycle. ER levels were very low in all three phases of the menstrual cycle. Conclusion: Significant variations in mRNA and protein levels of ER and PR were detected in skeletal muscle during three confirmed phases of the menstrual cycle. These results may have an impact on effects of muscular training and sports injuries in women.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Fysiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Physiology hsv//eng
- androgen receptor
- oestrogen receptor-alpha
- oestrogen receptor-beta
- progesterone receptor
- skeletal muscle
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Papoutsi, ZoiUppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Karolinska Inst, Novum, Dept Biosci & Nutr, Huddinge, Sweden.(Swepub:uu)zoipa253 (författare)
- Friden, C.Karolinska Institutet (författare)
- Wright, K. DahlmanKarolinska Institutet (författare)
- Hirschberg, A. LindenKarolinska Institutet (författare)
- Karolinska InstitutetCentrum för klinisk forskning i Sörmland (CKFD) (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Acta Physiologica: WILEY-BLACKWELL219:2, s. 486-4931748-17081748-1716
Internetlänk
Hitta mer i SwePub
- Av författaren/redakt...
- Ekenros, L.
- Papoutsi, Zoi
- Friden, C.
- Wright, K. Dahlm ...
- Hirschberg, A. L ...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Medicinska och f ...
- och Fysiologi
- Artiklar i publikationen
- Acta Physiologic ...
- Av lärosätet
- Uppsala universitet
- Karolinska Institutet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
