Sökning: WFRF:(Blancher Christine) >
Epigenome-wide asso...
-
Wahl, SimoneRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.;Univ Alexandria, Med Res Inst, Clin & Expt Surg Dept, Hadara, Alexandria 21561, Egypt.
(författare)
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
-
2016-12-21
-
NATURE PUBLISHING GROUP,2017
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:uu-319140
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-319140URI
-
https://doi.org/10.1038/nature20784DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of developing type (2) diabetes, cardiovascular disease and related metabolic and inflammatory disturbances(1,2). Although the mechanisms linking adiposity to associated clinical conditions are poorly understood, recent studies suggest that adiposity may influence DNA methylation(3-6), a key regulator of gene expression and molecular phenotype(7). Here we use epigenome-wide association to show that body mass index (BMI; a key measure of adiposity) is associated with widespread changes in DNA methylation (187 genetic loci with P < 1 x 10(-7), range P = 9.2 x 10(-8) to 6.0 x 10(-46); n = 10,261 samples). Genetic association analyses demonstrate that the alterations in DNA methylation are predominantly the consequence of adiposity, rather than the cause. We find that methylation loci are enriched for functional genomic features in multiple tissues (P < 0.05), and show that sentinel methylation markers identify gene expression signatures at 38 loci (P < 9.0 x 10(-6), range P = 5.5 x 10(-6) to 6.1 x 10(-35), n = 1,785 samples). The methylation loci identify genes involved in lipid and lipoprotein metabolism, substrate transport and inflammatory pathways. Finally, we show that the disturbances in DNA methylation predict future development of type 2 diabetes (relative risk per 1 standard deviation increase in methylation risk score: 2.3 (2.07-2.56); P = 1.1 x 10(-54)). Our results provide new insights into the biologic pathways influenced by adiposity, and may enable development of new strategies for prediction and prevention of type 2 diabetes and other adverse clinical consequences of obesity.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Drong, AlexanderUniv Oxford, Wellcome Trust Ctr Human Genet, Roosevelt Dr, Oxford OX3 7BN, England.
(författare)
-
Lehne, BenjaminImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.
(författare)
-
Loh, MarieImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.;Inst Hlth Sci, POB 5000, FI-90014 Oulu, Finland.;Translat Lab Genet Med TLGM, Agcy Sci, Technol & Res ASTAR, 8A Biomed Grove, Singapore 138648, Singapore.
(författare)
-
Scott, William R.Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.;Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.
(författare)
-
Kunze, SonjaRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.
(författare)
-
Tsai, Pei-ChienKings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.
(författare)
-
Ried, Janina S.German Res Ctr Environm Hlth, Inst Genet Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.
(författare)
-
Zhang, WeihuaImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.;Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.;Ealing Hosp NHS Trust, Middlesex UB1 3HW, England.
(författare)
-
Yang, YouwenImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.
(författare)
-
Tan, Sili
(författare)
-
Fiorito, GiovanniHuman Genet Fdn Torino, Turin, Italy.;Univ Torino, Dept Med Sci, Turin, Italy.
(författare)
-
Franke, LudeUniv Med Ctr Groningen, Dept Genet, NL-9700 RB Groningen, Netherlands.;Univ Groningen, NL-9700 AB Groningen, Netherlands.
(författare)
-
Guarrera, SimonettaHuman Genet Fdn Torino, Turin, Italy.;Univ Torino, Dept Med Sci, Turin, Italy.
(författare)
-
Kasela, SilvaUniv Tartu, Estonian Genome Ctr, Riia 23b, EE-51010 Tartu, Estonia.;Univ Tartu, Inst Mol & Cell Biol, Dept Biotechnol, Riia 23, EE-51010 Tartu, Estonia.
(författare)
-
Kriebel, JenniferRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.
(författare)
-
Richmond, Rebecca C.Univ Bristol, Sch Social & Community Med, MRC Integrat Epidemiol Unit, Bristol BS8 2BN, Avon, England.
(författare)
-
Adamo, MarcoUniv Coll London Hosp, UCLH Bariatr Ctr Weight Loss, Weight Management & Metab & Endocrine Surg, Ground Floor West Wing,250 Euston Rd, London NW1 2PG, England.
(författare)
-
Afzal, UzmaImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.;Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.;Ealing Hosp NHS Trust, Middlesex UB1 3HW, England.
(författare)
-
Ala-Korpela, MikaUniv Oulu & Biocenter Oulu, Computat Med, Fac Med, Oulu, Finland.;Univ Eastern Finland, Sch Pharm, NMR Metabol Lab, Kuopio, Finland.;Univ Bristol & Med Res Council Integrat Epidemiol, Univ Bristol, Sch Social & Community Med, Computat Med, Bristol, Avon, England.
(författare)
-
Albetti, BenedettaUniv Studi Milano & Fondazione IRCCS CaGranda Osp, Dept Clin Sci & Community Hlth, EPIGET Lab, Milan, Italy.
(författare)
-
Ammerpohl, OleUniv Hosp Schleswig Holstein, Inst Human Genet, Kiel Campus, Kiel, Germany.
(författare)
-
Apperley, Jane F.Imperial Coll London, Dept Med, Centre Haematol, Fac Med, Hammersmith Campus, London W12 0NN, England.
(författare)
-
Beekman, MarianLeiden Univ Med Ctr, Mol Epidemiol, NL-2333 ZC Leiden, Netherlands.
(författare)
-
Bertazzi, Pier AlbertoUniv Studi Milano & Fondazione IRCCS CaGranda Osp, Dept Clin Sci & Community Hlth, EPIGET Lab, Milan, Italy.
(författare)
-
Black, S. LucasImperial Coll London, Dept Med, Sect Infect Dis & Immun, London W12 0NN, England.
(författare)
-
Blancher, Christine
(författare)
-
Bonder, Marc-JanUniv Med Ctr Groningen, Dept Genet, NL-9700 RB Groningen, Netherlands.;Univ Groningen, NL-9700 AB Groningen, Netherlands.
(författare)
-
Brosch, MarioUniv Oxford, High Throughput Genom Oxford Genom Ctr, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.;Tech Univ Dresden, Univ Hosp, Med Dept 1, Dresden, Germany.
(författare)
-
Carstensen-Kirberg, MarenHeinrich Heine Univ Dusseldorf, German Diabet Ctr, Leibniz Ctr Diabet Res, Inst Clin Diabetol, Dusseldorf, Germany.
(författare)
-
de Craen, Anton J. M.Leiden Univ Med Ctr, Gerontol & Geriatr, NL-2300 RC Leiden, Netherlands.
(författare)
-
de Lusignan, SimonUniv Surrey, Dept Clin & Expt Med, Guildford GU2 7PX, Surrey, England.
(författare)
-
Dehghan, AbbasErasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
(författare)
-
Elkalaawy, MohamedUniv Coll London Hosp, UCLH Bariatr Ctr Weight Loss, Weight Management & Metab & Endocrine Surg, Ground Floor West Wing,250 Euston Rd, London NW1 2PG, England.;Univ Alexandria, Med Res Inst, Clin & Expt Surg Dept, Hadara, Alexandria 21561, Egypt.
(författare)
-
Fischer, KristaUniv Tartu, Estonian Genome Ctr, Riia 23b, EE-51010 Tartu, Estonia.
(författare)
-
Franco, Oscar H.Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
(författare)
-
Gaunt, Tom R.Univ Bristol, Sch Social & Community Med, MRC Integrat Epidemiol Unit, Bristol BS8 2BN, Avon, England.
(författare)
-
Hampe, JochenUniv Oxford, High Throughput Genom Oxford Genom Ctr, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England.
(författare)
-
Hashemi, MajidUniv Coll London Hosp, UCLH Bariatr Ctr Weight Loss, Weight Management & Metab & Endocrine Surg, Ground Floor West Wing,250 Euston Rd, London NW1 2PG, England.
(författare)
-
Isaacs, AaronErasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
(författare)
-
Jenkinson, AndrewUniv Coll London Hosp, UCLH Bariatr Ctr Weight Loss, Weight Management & Metab & Endocrine Surg, Ground Floor West Wing,250 Euston Rd, London NW1 2PG, England.
(författare)
-
Jha, SujeetDept Endocrinol, Diabet & Obes, Max Healthcare, New Delhi 110017, India.
(författare)
-
Kato, NorihiroRes Inst, Natl Ctr Global Hlth & Med, Dept Gene Diagnost & Therapeut, Tokyo 1628655, Japan.
(författare)
-
Krogh, VittorioEpidemiol & Prevent Unit, Fondazione IRCSS Ist Nazl Tumori, Milan, Italy.
(författare)
-
Laffan, MichaelImperial Coll London, Dept Med, Centre Haematol, Fac Med, Hammersmith Campus, London W12 0NN, England.
(författare)
-
Meisinger, ChristaInst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.
(författare)
-
Meitinger, ThomasGerman Res Ctr Environm Hlth, Int Human Genet, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Tech Univ Munich, Inst Human Genet, Munich, Germany.;Partner site Munich Heart Alliance, DZHK German Ctr Cardiovasc Res, Munich, Germany.
(författare)
-
Mok, Zuan YuNatl Univ Singapore, Cancer Sci Inst Singapore, Singapore, Singapore.
(författare)
-
Motta, ValeriaUniv Studi Milano & Fondazione IRCCS CaGranda Osp, Dept Clin Sci & Community Hlth, EPIGET Lab, Milan, Italy.;Partner site Munich Heart Alliance, DZHK German Ctr Cardiovasc Res, Munich, Germany.
(författare)
-
Ng, Hong KiatNatl Univ Singapore, Cancer Sci Inst Singapore, Singapore, Singapore.
(författare)
-
Nikolakopoulou, ZacharoulaNatl Heart & Lung Inst, London SW3 6LY, England.
(författare)
-
Nteliopoulos, GeorgiosImperial Coll London, Dept Med, Centre Haematol, Fac Med, Hammersmith Campus, London W12 0NN, England.
(författare)
-
Panico, SalvatoreDipartmento Med Clin Chirurgia Federio II Univ, Naples, Italy.
(författare)
-
Pervjakova, NataliaUniv Tartu, Estonian Genome Ctr, Riia 23b, EE-51010 Tartu, Estonia.;Univ Tartu, Inst Mol & Cell Biol, Dept Biotechnol, Riia 23, EE-51010 Tartu, Estonia.
(författare)
-
Prokisch, HolgerTech Univ Munich, Inst Human Genet, Munich, Germany.
(författare)
-
Rathmann, WolfgangHeinrich Heine Univ Dusseldorf, German Diabet Ctr, Leibniz Ctr Diabet Res, Inst Biometr & Epidemiol, Dusseldorf, Germany.
(författare)
-
Roden, MichaelGerman Ctr Diabet Res DZD, Neuherberg, Germany.;Heinrich Heine Univ Dusseldorf, German Diabet Ctr, Leibniz Ctr Diabet Res, Inst Clin Diabetol, Dusseldorf, Germany.;Heinrich Heine Univ Hosp Dusseldorf, Fac Med, Dept Endocrinol & Diabetol, Dusseldorf, Germany.
(författare)
-
Rota, FedericaUniv Studi Milano & Fondazione IRCCS CaGranda Osp, Dept Clin Sci & Community Hlth, EPIGET Lab, Milan, Italy.
(författare)
-
Rozario, Michelle Ann
(författare)
-
Sandling, Johanna K.Uppsala universitet,Molekylär medicin,Science for Life Laboratory, SciLifeLab,Wellcome Trust Sanger Inst, Wellcome Trust Genome Campus, Hinxton, England.(Swepub:uu)josan062
(författare)
-
Schafmayer, ClemensUniv Hosp Schleswig Holstein, Dept Visceral & Thorac Surg, Kiel Campus, Kiel, Germany.
(författare)
-
Schramm, KatharinaTech Univ Munich, Inst Human Genet, Munich, Germany.
(författare)
-
Siebert, ReinerUniv Hosp Schleswig Holstein, Inst Human Genet, Kiel Campus, Kiel, Germany.;Univ Hosp Ulm, Inst Human Genet, Albert Einstein Allee 11, D-89081 Ulm, Germany.
(författare)
-
Slagboom, P. ElineLeiden Univ Med Ctr, Mol Epidemiol, NL-2333 ZC Leiden, Netherlands.
(författare)
-
Soininen, PasiUniv Oulu & Biocenter Oulu, Computat Med, Fac Med, Oulu, Finland.;Univ Eastern Finland, Sch Pharm, NMR Metabol Lab, Kuopio, Finland.
(författare)
-
Stolk, LisetteErasmus MC, Dept Internal Med, Rotterdam, Netherlands.
(författare)
-
Strauch, KonstantinGerman Res Ctr Environm Hlth, Inst Genet Epidemiol, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Ludwig Maximilians Univ Munchen, Inst Med Informat, Biometry & Epidemiol, Chair Genet Epidemiol, Munich, Germany.
(författare)
-
Tai, E-ShyongNatl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore 119228, Singapore.;Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117597, Singapore.;Duke Natl Univ, Singapore Grad Med Sch, Singapore 169857, Singapore.
(författare)
-
Tarantini, LetiziaUniv Studi Milano & Fondazione IRCCS CaGranda Osp, Dept Clin Sci & Community Hlth, EPIGET Lab, Milan, Italy.
(författare)
-
Thorand, BarbaraInst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.
(författare)
-
Tigchelaar, Ettje F.Univ Med Ctr Groningen, Dept Genet, NL-9700 RB Groningen, Netherlands.;Univ Groningen, NL-9700 AB Groningen, Netherlands.
(författare)
-
Tumino, RosarioCancer Registry & Histopathol Unit, Civile MP Arezzo Hosp, ASP 7, Ragusa, Italy.
(författare)
-
Uitterlinden, Andre G.Erasmus MC, Dept Internal Med & Epidemiol, Rotterdam, Netherlands.
(författare)
-
van Duijn, CorneliaErasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
(författare)
-
van Meurs, Joyce B. J.Erasmus MC, Dept Internal Med, Rotterdam, Netherlands.
(författare)
-
Vineis, PaoloImperial Coll London, Epidemiol & Publ Hlth, London, England.
(författare)
-
Wickremasinghe, Ananda RajithaUniv Kelaniya, Dept Publ Hlth, Fac Med, Box 6,Thalagolla Rd, Ragama 11010, Sri Lanka.
(författare)
-
Wijmenga, CiscaUniv Med Ctr Groningen, Dept Genet, NL-9700 RB Groningen, Netherlands.;Univ Groningen, NL-9700 AB Groningen, Netherlands.
(författare)
-
Yang, Tsun-Po
(författare)
-
Yuan, WeiKings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.;Inst Canc Res, Surrey SM2 5NG, England.
(författare)
-
Zhernakova, AlexandraUniv Med Ctr Groningen, Dept Genet, NL-9700 RB Groningen, Netherlands.;Univ Groningen, NL-9700 AB Groningen, Netherlands.
(författare)
-
Batterham, Rachel L.Univ Coll London Hosp, UCLH Bariatr Ctr Weight Loss, Weight Management & Metab & Endocrine Surg, Ground Floor West Wing,250 Euston Rd, London NW1 2PG, England.;UCL, Rayne Inst, Dept Med, Ctr Obes Res, London WC1E 6JJ, England.
(författare)
-
Smith, George DaveyUniv Bristol, Sch Social & Community Med, MRC Integrat Epidemiol Unit, Bristol BS8 2BN, Avon, England.
(författare)
-
Deloukas, PanosQueen Mary Univ London, William Harvey Res Inst, Barts & London Sch Med & Dent, London EC1M 6BQ, England.;King Abdulaziz Univ, Princess Jawhara Brahim Ctr Excellence Res Heredi, Jeddah 21589, Saudi Arabia.
(författare)
-
Heijmans, Bastiaan T.
(författare)
-
Herder, ChristianGerman Ctr Diabet Res DZD, Neuherberg, Germany.;Heinrich Heine Univ Dusseldorf, German Diabet Ctr, Leibniz Ctr Diabet Res, Inst Clin Diabetol, Dusseldorf, Germany.
(författare)
-
Hofman, AlbertErasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
(författare)
-
Lindgren, Cecilia M.Broad Inst, Massachusetts Inst Technol & Harvard Univ, Cambridge, MA 02142 USA.
(författare)
-
Milani, LiliUniv Tartu, Estonian Genome Ctr, Riia 23b, EE-51010 Tartu, Estonia.
(författare)
-
van der Harst, PimUniv Med Ctr Groningen, Dept Cardiol, Univ Groningen, NL-9700 RB Groningen, Netherlands.;ICIN Netherlands Heart Inst, Durrer Ctr Cardiogenet Res, NL-3511 GC Utrecht, Netherlands.
(författare)
-
Peters, AnnetteGerman Ctr Diabet Res DZD, Neuherberg, Germany.;Partner site Munich Heart Alliance, DZHK German Ctr Cardiovasc Res, Munich, Germany.
(författare)
-
Illig, ThomasRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Hannover Med Sch, Hannover Unified Biobank, Feodor Lynen St 15, Hannover, Germany.;Hannover Med Sch, Inst Human Genet, Carl Neuberg St 1, Hannover, Germany.
(författare)
-
Relton, Caroline L.Univ Bristol, Sch Social & Community Med, MRC Integrat Epidemiol Unit, Bristol BS8 2BN, Avon, England.
(författare)
-
Waldenberger, MelanieRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.
(författare)
-
Jaervelin, Marjo-RiittaImperial Coll London, Sch Publ Hlth, MRC Hlth Protect Agcy HPE Ctr Environm & Hlth, Dept Epidemiol & Biostatist, London, England.;Univ Oulu, Bioctr Oulu, POB 5000, Oulu, Finland.;Univ Oulu, Ctr Life Course Epidemiol, Fac Med, POB 5000, Oulu 90014, Finland.;Oulu Univ Hosp, Unit Primary Care, Kajaanintie 50,Box 20, Oulu, Finland.
(författare)
-
Bollati, ValentinaUniv Studi Milano & Fondazione IRCCS CaGranda Osp, Dept Clin Sci & Community Hlth, EPIGET Lab, Milan, Italy.
(författare)
-
Soong, RichieNatl Univ Singapore, Cancer Sci Inst Singapore, Singapore, Singapore.;Natl Univ Singapore Hosp, Dept Pathol, Singapore, Singapore.
(författare)
-
Spector, Tim D.Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.
(författare)
-
Scott, JamesImperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.
(författare)
-
McCarthy, Mark I.Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, England.;Oxford NIHR Biomed Res Ctr, Churchill Hosp, Oxford OX3 7LJ, England.
(författare)
-
Elliott, PaulImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.
(författare)
-
Bell, Jordana T.Kings Coll London, Dept Twin Res & Genet Epidemiol, London SE1 7EH, England.
(författare)
-
Matullo, GiuseppeHuman Genet Fdn Torino, Turin, Italy.;Univ Torino, Dept Med Sci, Turin, Italy.
(författare)
-
Gieger, ChristianRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.
(författare)
-
Kooner, Jaspal S.Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.;Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.;Ealing Hosp NHS Trust, Middlesex UB1 3HW, England.;Imperial Coll Healthcare NHS Trust, London W12 0HS, England.
(författare)
-
Grallert, HaraldRes Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.;Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.
(författare)
-
Chambers, John C.Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostatist, MRC PHE Ctr Environm & Hlth, London W2 1PG, England.;Imperial Coll London, Natl Heart & Lung Inst, London W12 0NN, England.;Ealing Hosp NHS Trust, Middlesex UB1 3HW, England.;Imperial Coll Healthcare NHS Trust, London W12 0HS, England.;Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore, Singapore.
(författare)
-
Res Unit Mol Epidemiol, German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Neuherberg, Germany.;Inst Epidemiol II, German Res Ctr Environm Hlth, Helmholtz Zentrum M nchen, Neuherberg, Germany.;German Ctr Diabet Res DZD, Neuherberg, Germany.;Univ Alexandria, Med Res Inst, Clin & Expt Surg Dept, Hadara, Alexandria 21561, Egypt.Univ Oxford, Wellcome Trust Ctr Human Genet, Roosevelt Dr, Oxford OX3 7BN, England.
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Nature: NATURE PUBLISHING GROUP541:7635, s. 81-+0028-08361476-4687
Internetlänk
Hitta via bibliotek
-
Nature
(Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- Av författaren/redakt...
-
Wahl, Simone
-
Drong, Alexander
-
Lehne, Benjamin
-
Loh, Marie
-
Scott, William R ...
-
Kunze, Sonja
-
visa fler...
-
Tsai, Pei-Chien
-
Ried, Janina S.
-
Zhang, Weihua
-
Yang, Youwen
-
Tan, Sili
-
Fiorito, Giovann ...
-
Franke, Lude
-
Guarrera, Simone ...
-
Kasela, Silva
-
Kriebel, Jennife ...
-
Richmond, Rebecc ...
-
Adamo, Marco
-
Afzal, Uzma
-
Ala-Korpela, Mik ...
-
Albetti, Benedet ...
-
Ammerpohl, Ole
-
Apperley, Jane F ...
-
Beekman, Marian
-
Bertazzi, Pier A ...
-
Black, S. Lucas
-
Blancher, Christ ...
-
Bonder, Marc-Jan
-
Brosch, Mario
-
Carstensen-Kirbe ...
-
de Craen, Anton ...
-
de Lusignan, Sim ...
-
Dehghan, Abbas
-
Elkalaawy, Moham ...
-
Fischer, Krista
-
Franco, Oscar H.
-
Gaunt, Tom R.
-
Hampe, Jochen
-
Hashemi, Majid
-
Isaacs, Aaron
-
Jenkinson, Andre ...
-
Jha, Sujeet
-
Kato, Norihiro
-
Krogh, Vittorio
-
Laffan, Michael
-
Meisinger, Chris ...
-
Meitinger, Thoma ...
-
Mok, Zuan Yu
-
Motta, Valeria
-
Ng, Hong Kiat
-
Nikolakopoulou, ...
-
Nteliopoulos, Ge ...
-
Panico, Salvator ...
-
Pervjakova, Nata ...
-
Prokisch, Holger
-
Rathmann, Wolfga ...
-
Roden, Michael
-
Rota, Federica
-
Rozario, Michell ...
-
Sandling, Johann ...
-
Schafmayer, Clem ...
-
Schramm, Kathari ...
-
Siebert, Reiner
-
Slagboom, P. Eli ...
-
Soininen, Pasi
-
Stolk, Lisette
-
Strauch, Konstan ...
-
Tai, E-Shyong
-
Tarantini, Letiz ...
-
Thorand, Barbara
-
Tigchelaar, Ettj ...
-
Tumino, Rosario
-
Uitterlinden, An ...
-
van Duijn, Corne ...
-
van Meurs, Joyce ...
-
Vineis, Paolo
-
Wickremasinghe, ...
-
Wijmenga, Cisca
-
Yang, Tsun-Po
-
Yuan, Wei
-
Zhernakova, Alex ...
-
Batterham, Rache ...
-
Smith, George Da ...
-
Deloukas, Panos
-
Heijmans, Bastia ...
-
Herder, Christia ...
-
Hofman, Albert
-
Lindgren, Cecili ...
-
Milani, Lili
-
van der Harst, P ...
-
Peters, Annette
-
Illig, Thomas
-
Relton, Caroline ...
-
Waldenberger, Me ...
-
Jaervelin, Marjo ...
-
Bollati, Valenti ...
-
Soong, Richie
-
Spector, Tim D.
-
Scott, James
-
McCarthy, Mark I ...
-
Elliott, Paul
-
Bell, Jordana T.
-
Matullo, Giusepp ...
-
Gieger, Christia ...
-
Kooner, Jaspal S ...
-
Grallert, Harald
-
Chambers, John C ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Allmänmedicin
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Endokrinologi oc ...
- Artiklar i publikationen
-
Nature
- Av lärosätet
-
Uppsala universitet